Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Hans P. M. M. Lauritzen"'
Autor:
Mengyao Ella Li, Hans P. M. M. Lauritzen, Brian T. O’Neill, Chih-Hao Wang, Weikang Cai, Bruna B. Brandao, Masaji Sakaguchi, Rongya Tao, Michael F. Hirshman, Samir Softic, C. Ronald Kahn
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Diabetes is associated with decreased PI3K activation in skeletal muscle. Here, the authors show that p110a is the predominant PI3K subunit in muscle, and show that its ablation in muscle, but not ablation of p110beta, leads to insulin resistance, in
Externí odkaz:
https://doaj.org/article/dd1ee7415b94490ba84eaa4f18e22335
Autor:
Hans P M M, Lauritzen
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 637
Skeletal muscle plays a key role in regulating whole body glucose homeostasis and severe dysfunction in insulin-mediated glucose uptake is the hallmark of insulin-resistant states and type II diabetes. Therefore it is highly pathophysiologically rele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a23d685b27fdc898e9c0214b56fc70df
https://pubmed.ncbi.nlm.nih.gov/20419438
https://pubmed.ncbi.nlm.nih.gov/20419438
Autor:
Hans P M M, Lauritzen
Publikováno v:
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme. 34(3)
In skeletal muscle, both insulin and muscle contractions mediate translocation of glucose transporter GLUT4 to the plasma membrane proper, the sarcolemma, and the specialized membrane channel network, the transverse (t)-tubules. Despite the fact that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b79e244ab2975684726cf59990d0b9c6
https://pubmed.ncbi.nlm.nih.gov/19448708
https://pubmed.ncbi.nlm.nih.gov/19448708
Publikováno v:
Diabetes. 57(2)
Insulin stimulates glucose transport in skeletal muscle by GLUT4 translocation from intracellular compartments to sarcolemma and t-tubules. We studied in living animals the recruitment of GLUT4 vesicles in more detail than previously done and, for th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5497668979c7fe7a0127e6d69ba2500e
https://pubmed.ncbi.nlm.nih.gov/17977960
https://pubmed.ncbi.nlm.nih.gov/17977960