Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Hans P, Wendel"'
Autor:
Danmei Xu, Findlay Bewicke-Copley, Karina Close, Jessica Okosun, Robert Peter Gale, Jane Apperley, David M. Weinstock, Hans-Guido Wendel, Jude Fitzgibbon
Publikováno v:
Blood Cancer Journal, Vol 14, Iss 1, Pp 1-4 (2024)
Externí odkaz:
https://doaj.org/article/091cc56248bf4dceb9867bb651ad6600
Autor:
Josefin Weber, Carsten Linti, Christiane Lörch, Marbod Weber, Madelene Andt, Christian Schlensak, Hans Peter Wendel, Michael Doser, Meltem Avci-Adali
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract The liver is a vital organ with numerous functions, including metabolic functions, detoxification, and the synthesis of secretory proteins. The increasing prevalence of liver diseases requires the development of effective treatments, models,
Externí odkaz:
https://doaj.org/article/8ce0e14443554919a9f0af2306140695
Autor:
Sonia Golombek, Thomas Hoffmann, Ludmilla Hann, Markus Mandler, Sabine Schmidhuber, Josefin Weber, Young-Tae Chang, Roman Mehling, Andrea Ladinig, Christian Knecht, Johanna Leyens, Christian Schlensak, Hans Peter Wendel, Achim Schneeberger, Meltem Avci-Adali
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 642-654 (2023)
Loss of elastin due to aging, disease, or injury can lead to impaired tissue function. In this study, de novo tropoelastin (TE) synthesis is investigated in vitro and in vivo using different TE-encoding synthetic mRNA variants after codon optimizatio
Externí odkaz:
https://doaj.org/article/fb35e12ee64a40e1bef0ae30f9a604f7
Autor:
Ana Portelinha, Mariana da Silva Ferreira, Tatiana Erazo, Man Jiang, Zahra Asgari, Elisa de Stanchina, Anas Younes, Hans-Guido Wendel
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Genomic instability occurs infrequently in in diffuse large B cell lymphoma (DLBCL), suggesting a therapeutic vulnerability. Here, the authors identify a synergistic combination between the induction of polyploidy by a PLK4 inhibitor and a BCL-2 inhi
Externí odkaz:
https://doaj.org/article/10d2ea4c9cf4467884462bb93e66c548
Autor:
Tiago Granja, Harry Magunia, Patricia Schüssel, Claudius Fischer, Thomas Prüfer, David Schibilsky, Lina Serna-Higuita, Hans Peter Wendel, Christian Schlensak, Helene Häberle, Peter Rosenberger, Andreas Straub
Publikováno v:
Platelets, Vol 33, Iss 1, Pp 132-140 (2022)
Blood flow through left ventricular assist devices (LVAD) may induce activation and dysfunction of platelets. Dysfunctional platelets cause coagulation disturbances and form platelet-neutrophil conjugates (PNC), which contribute to inflammatory tissu
Externí odkaz:
https://doaj.org/article/224193a79db94d35ab1add160e7ab36f
Autor:
Yan Xu, Yichen Xu, Wentai Zhang, Ming Li, Hans-Peter Wendel, Jürgen Geis-Gerstorfer, Ping Li, Guojiang Wan, Shulan Xu, Tao Hu
Publikováno v:
Frontiers in Chemistry, Vol 10 (2022)
Zinc-based nanoparticles, nanoscale metal frameworks and metals have been considered as biocompatible materials for bone tissue engineering. Among them, zinc-based metals are recognized as promising biodegradable materials thanks to their moderate de
Externí odkaz:
https://doaj.org/article/e301321faddf4269828f139c8a8ec136
Autor:
Débora Ferreira, Joaquim Barbosa, Diana A. Sousa, Cátia Silva, Luís D. R. Melo, Meltem Avci-Adali, Hans P. Wendel, Ligia R. Rodrigues
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Triple-negative breast cancer is the most aggressive subtype of invasive breast cancer with a poor prognosis and no approved targeted therapy. Hence, the identification of new and specific ligands is essential to develop novel targeted thera
Externí odkaz:
https://doaj.org/article/6c99aaffdcdf46e9a9583ba91d206a71
Publikováno v:
Bioengineering, Vol 10, Iss 4, p 411 (2023)
Polytetrafluoroethylene (PTFE) is a commonly used biomaterial for the manufacturing of vascular grafts and several strategies, such as coatings, have been explored to improve the hemocompatibility of small-diameter prostheses. In this study, the hemo
Externí odkaz:
https://doaj.org/article/5b4801f544da40a685f7d294bbb66659
Autor:
Susanne Schiffmann, Marina Henke, Michelle Seifert, Thomas Ulshöfer, Luise A. Roser, Francesca Magari, Hans-Guido Wendel, Arnold Grünweller, Michael J. Parnham
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5872 (2023)
A promising new approach to broad spectrum antiviral drugs is the inhibition of the eukaryotic translation initiation factor 4A (elF4A), a DEAD-box RNA helicase that effectively reduces the replication of several pathogenic virus types. Beside the an
Externí odkaz:
https://doaj.org/article/20304e90eded43f5addbbb288ee210d7
Autor:
David Schibilsky, Setsuo Takatani, Barbara Schibilsky, Tobias Graf, Diana Michels da Silva, Hans Peter Wendel, Meltem Avci-Adali, Christian Schlensak
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-8 (2020)
Abstract The specific hemocompatibility properties of mechanical-circulatory-support (MCS)-pump technologies have not previously been described in a comparable manner. We thus investigated the hemocompatibility-indicating marker of a new magnetically
Externí odkaz:
https://doaj.org/article/3c09ace527474b75b80c2b7b34381cb0