Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Hans Michael Wolff"'
Autor:
Martin Alexander Schubert, Clémence Chenevas-Paule, Mark Ashton, Kalliopi Dodou, Hans-Michael Wolff
Drug crystallization in transdermal drug delivery systems is a critical quality defect. The impact of drug load and hydration on the physical stability of polar (acrylic) drug-in-adhesive (DIA) films was investigated with the objective to identify pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db083f22b128e9060ff41571072a7199
Publikováno v:
Pharmaceutical Research
Purpose\ud We aimed to investigate the effect of solubility parameter and drug concentration on the rheological behaviour of drug-in-adhesive films intended for transdermal application.\ud \ud Methods\ud Films were prepared over a range of drug conce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91534dff63a0ff2aa59c518df43cd040
https://doi.org/10.1007/s11095-014-1318-2
https://doi.org/10.1007/s11095-014-1318-2
Autor:
Kalliopi Dodou, Hans-Michael Wolff, Clémence Chenevas-Paule, Mark Ashton, Martin Alexander Schubert
Publikováno v:
Journal of pharmaceutical sciences. 106(5)
Microreservoir-type transdermal drug delivery systems (MTDDS) can prevent drug crystallization; however, no current predictive model considers the impact of drug load and hydration on their physical stability. We investigated MTDDS films containing p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10655677fc303efc8954691a093fdec0
https://pubmed.ncbi.nlm.nih.gov/28163134
https://pubmed.ncbi.nlm.nih.gov/28163134
Autor:
Hans-Michael Wolff
Publikováno v:
Pharmaceutical Science & Technology Today. 3:173-181
In a pharmaceutical market characterized by increasing competition, assessment criteria related to system design are assuming greater importance. This is true for both conventional dosage forms and drug delivery systems (DDS), as manufacturers strive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0de1ddcb74386d52f5097ce02377892
https://doi.org/10.1016/s1461-5347(00)00251-0
https://doi.org/10.1016/s1461-5347(00)00251-0
Publikováno v:
International Journal of Pharmaceutics. 148:55-61
In vitro 17β-estradiol release from controlled-release microspheres intended for intra-muscular administration was investigated using a rotating bottle apparatus. Prior to intra-muscular administration of 17β-estradiol loaded microspheres the in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f1582a6ae0198f77ca92ce1f8bdd1a5
https://doi.org/10.1016/s0378-5173(96)04823-5
https://doi.org/10.1016/s0378-5173(96)04823-5
Publikováno v:
Drugs of today (Barcelona, Spain : 1998). 46(7)
The nonergoline dopamine agonist rotigotine, is delivered transdermally using a silicone-based patch (Neupro(R); UCB Pharma GmbH), which promotes unidirectional drug flow from the transdermal system to the skin. Pharmacokinetic data show stable stead
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef2b18ac155bbee66fb4eae59a10550
https://pubmed.ncbi.nlm.nih.gov/20683503
https://pubmed.ncbi.nlm.nih.gov/20683503
Publikováno v:
Clinical Pharmacokinetics, 10, 46, 851-857
Background and objective: The dopamine agonist rotigotine has been formulated in a silicone-based transdermal system for once-daily administration. The objective of the present study was to characterise the mass balance of rotigotine in humans after
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2d8fbcbe102a45e9d9b08a8717cb1b
http://resolver.tudelft.nl/uuid:89e23302-aa1b-425b-b8db-04b1c2ca12a8
http://resolver.tudelft.nl/uuid:89e23302-aa1b-425b-b8db-04b1c2ca12a8
Publikováno v:
Journal of Pharmacy and Pharmacology. 60:A-53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba70d2e983351f01b87974ed58e2fdaa
https://doi.org/10.1211/002235708785623345
https://doi.org/10.1211/002235708785623345
Autor:
Hans-Michael Wolff
Publikováno v:
Die Haut als Transportorgan für Arzneistoffe ISBN: 9783642724534
An Beispielen von wirkstoffbeladenen Adhasivfihnen werden Konzepte, Herstellmethoden und galenische Optimierungsmoglichkeiten in der TTS-Entwicklung skizziert. Abgesehen von biologischen Faktoren sind fur die in-vivo-Freisetzung Steuerungselemente, R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecca2b2b8ef886cde8ed0cefc17f6cbe
https://doi.org/10.1007/978-3-642-72452-7_13
https://doi.org/10.1007/978-3-642-72452-7_13