Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Hans Mechler"'
Publikováno v:
Brain Research. 837:193-202
Proteases are expressed widely throughout the nervous system and perform essential functions. We have earlier characterized and cloned the metalloprotease MP100, an enzyme originally described as a beta-amyloid precursor protein (beta-APP) processing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee819784f311972cd78406ce28b92d4
https://doi.org/10.1016/s0006-8993(99)01693-5
https://doi.org/10.1016/s0006-8993(99)01693-5
Autor:
Konrad Beyreuther, R.B. Banati, C.L. Masters, G. König, Hans Mechler, Christian Czech, U Schreiter-Gasser, J Gehrmann, Ursula Mönning
Publikováno v:
Journal of Biological Chemistry. 267:23950-23956
The mechanism of proteolytic breakdown of the beta A4-amyloid protein precursor (APP) has attracted much attention because of its relevance for Alzheimer's disease. Apart from the pathological role of APP in the amyloidogenesis, many efforts have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfb4138e01cefb6f3d28b1f306d57973
https://doi.org/10.1016/s0021-9258(18)35929-5
https://doi.org/10.1016/s0021-9258(18)35929-5
Publikováno v:
Nucleic Acids Research. 19:4909-4914
We have isolated cDNAs coding for a ribonucleoprotein of Drosophila melanogaster that is distinguished by its nearly exclusive presence at only one of the several heat shock puffs in polytene chromosomes of third instar larvae. We determined the nucl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::229eedcde277d6c288f4f01b8d8f2407
https://doi.org/10.1093/nar/19.18.4909
https://doi.org/10.1093/nar/19.18.4909
Autor:
Remo Hochstrasser, Hans Mechler, Pari Malherbe, A. Thompson, Gerda Huber, Hans‐Peter Hauri, Fiona Grüninger
Publikováno v:
Journal of neurochemistry. 72(3)
Metalloprotease MP100 was originally isolated as a beta-secretase candidate from human brain using a beta-amyloid precursor protein (beta-APP)-derived p-nitroanilide (pNA) peptide substrate. Peptide sequences from purified MP100 were now found to res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97f4a67f96a84e2da6301e7c7e02cc56
https://pubmed.ncbi.nlm.nih.gov/10037494
https://pubmed.ncbi.nlm.nih.gov/10037494
Autor:
R. Prior, G. König, Ursula Schreiter-Gasser, Konrad Beyreuther, Ursula Mönning, Hans Mechler, Colin L. Masters
Publikováno v:
FEBS letters. 277(1-2)
Alzheimer amyloid precursor proteins (APP) are actively secreted by stimulated human peripheral mononuclear blood leucocytes (PMBLs). Induction of APP transcription, translation and secretion was observed with several T cell mitogens but was highest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bd5597092a1f99b46941caafe2fe7ca
https://pubmed.ncbi.nlm.nih.gov/2125277
https://pubmed.ncbi.nlm.nih.gov/2125277
Autor:
C.L. Masters, Caroline Hilbich, R. Prior, Hans Mechler, Thomas Dyrks, J. Beer, N. Catteruccia, E. Mack-Kühn, Andreas Weidemann, Walter Schubert, Gerd Multhaup, J.M. Salbaum, G. König, Tetsuyuki Kitamoto, Peter Fischer, Ursula Mönning, D. Bunke, Konrad Beyreuther, E. Schlichtmann
Publikováno v:
Neurobiology of Aging. 11:299
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::356076391cd0b7f7eecacff16a94336f
https://doi.org/10.1016/0197-4580(90)90745-l
https://doi.org/10.1016/0197-4580(90)90745-l
Publikováno v:
Neurobiology of Aging. 11:323
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::534a336c8032783b03ecb7be83c4fddb
https://doi.org/10.1016/0197-4580(90)90844-p
https://doi.org/10.1016/0197-4580(90)90844-p