Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Hans Juergen Kuehnel"'
Publikováno v:
Pediatric hematology and oncology. 29(2)
The main aim of this analysis was to characterize the population pharmacokinetics of native Escherichia coli asparaginase (ASNase medac) in pediatric patients with previously untreated acute lymphoblastic leukemia. Secondary objective was to give fur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1313e3311393e9094df1670ef674650e
https://pubmed.ncbi.nlm.nih.gov/22376019
https://pubmed.ncbi.nlm.nih.gov/22376019
Autor:
Charlotte O'Horo, Jeremy Hancock, Ashish Masurekar, Anthony V. Moorman, Adiba Hussain, Catriona Parker, Nicholas Goulden, Sue Richards, Genevieve Pridham, Caroline Yk Fong, Debbie Payne, Monika Essink, Vaskar Saha, Shekhar Krishnan, Jizhong Liu, Hans Juergen Kuehnel, Donna Lancaster, Ajay Vora
Publikováno v:
BLOOD. 118(21)
Abstract 2573 Introduction: Polyethylene glycol conjugated L-asparaginase (PEG-ASNase) is used in varying doses between 1000–2500 U/m2 in the therapy of ALL and associated with a wide variation in pharmacokinetics. UKALL 2003 used intramuscular PEG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e105c09a51d13f62ed33e5b5d17f7a6f
http://ora.ox.ac.uk/objects/uuid:400df42f-7d23-48c2-8573-2736835d0593
http://ora.ox.ac.uk/objects/uuid:400df42f-7d23-48c2-8573-2736835d0593
Autor:
Hans-Juergen Kuehnel, Rob Pieters, Uwe Pichlmeier, Eline G. Visser, Rolinda Stigter, Inekee van der Vaart, Inge M. Appel, Iris Tetzlaff-Fohr
Publikováno v:
Blood, 112(13), 4832-4838. American Society of Hematology
The pharmacokinetics, pharmacodynamics, efficacy, and safety of a new recom-binant Escherichia coli–asparaginase preparation was compared with Asparaginase medac. Thirty-two children with acute lymphoblastic leukemia were randomized to receive one
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f2582638d64e2a38b707b2b9db9dc43
https://pubmed.ncbi.nlm.nih.gov/18805963
https://pubmed.ncbi.nlm.nih.gov/18805963
Autor:
Wing H. Tong, Rob Pieters, Gertjan Kaspers, Maroeska D.W.M. te Loo, Marc Bierings, Cor van den Bos, Wouter J.W. Kollen, Wim C.J. Hop, Joachim Boos, Mary V. Relling, Hans Juergen Kuehnel, Wim J Tissing, Inge M. van der Sluis
Publikováno v:
Blood. 122:2634-2634
Purpose A prospective drug monitoring study was performed to analyse the efficacy of very prolonged use of PEGasparaginase and Erwiniaasparaginase by assessing asparaginase activity, asparagine, glutamine levels and asparaginase antibodies in childre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4dbf0827993da8bef338cd8d710385f4
https://doi.org/10.1182/blood.v122.21.2634.2634
https://doi.org/10.1182/blood.v122.21.2634.2634
Publikováno v:
Blood. 114:4803-4803
Abstract 4803 Introduction Native Escherichia Coli Asparaginase (ASNase) is an integral component in the therapy of acute lymphoblastic leukemia (ALL) and non-Hodgkin's Lymphoma (NHL). There is a great interindividual variability in treatment intensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c86af2d849e8d1ac269665db5f5bd226
https://doi.org/10.1182/blood.v114.22.4803.4803
https://doi.org/10.1182/blood.v114.22.4803.4803