Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Hans Joachim, Räder"'
Autor:
Collin Zimmer, Jan Brauer, Dorota Ferenc, Jessica Meyr, Patrick Müller, Hans-Joachim Räder, Bernd Engels, Till Opatz, Tanja Schirmeister
Publikováno v:
Molecules, Vol 29, Iss 11, p 2660 (2024)
The aim of this study was to investigate the transition from non-covalent reversible over covalent reversible to covalent irreversible inhibition of cysteine proteases by making delicate structural changes to the warhead scaffold. To this end, dipept
Externí odkaz:
https://doaj.org/article/60ad1902ed054cbca788414b67730366
Autor:
Nilanjon Naskar, Manfred Wagner, Hans Joachim Räder, Haoyuan Qi, Ute Kaiser, Tanja Weil, Sabyasachi Chakrabortty
Publikováno v:
Advanced Photonics Research, Vol 3, Iss 2, Pp n/a-n/a (2022)
The structure formation of carbon nanodots (C‐dots) prepared from three different organic precursors is discussed at the molecular level. During microwave synthesis, organic chromophores associated with C‐dot structures are formed that exhibit di
Externí odkaz:
https://doaj.org/article/5268f1bdc50540c5a279b81feed1133f
Autor:
Fabian Barthels, Jessica Meyr, Stefan J. Hammerschmidt, Tessa Marciniak, Hans-Joachim Räder, Wilma Ziebuhr, Bernd Engels, Tanja Schirmeister
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2022)
Staphylococcus aureus is one of the most frequent causes of nosocomial and community-acquired infections, with emerging multiresistant isolates causing a significant burden to public health systems. We identified 2-sulfonylpyrimidines as a new class
Externí odkaz:
https://doaj.org/article/205856979c4443d6a482b2392856ebe8
Autor:
Evangelia Bolli, Maximilian Scherger, Sana M. Arnouk, Ana Rita Pombo Antunes, David Straßburger, Moritz Urschbach, Judith Stickdorn, Karen De Vlaminck, Kiavash Movahedi, Hans Joachim Räder, Sophie Hernot, Pol Besenius, Jo A. Van Ginderachter, Lutz Nuhn
Publikováno v:
Advanced Science, Vol 8, Iss 10, Pp n/a-n/a (2021)
Abstract Tumor‐associated macrophages (TAMs) promote the immune suppressive microenvironment inside tumors and are, therefore, considered as a promising target for the next generation of cancer immunotherapies. To repolarize their phenotype into a
Externí odkaz:
https://doaj.org/article/cac8fa4c5d6f47508fc134a4bcd703ea
Publikováno v:
ACS Biomaterials Science & Engineering.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4932a89e2ffeaf7fe8a8104ffddaf0c2
https://doi.org/10.1021/acsbiomaterials.2c01106
https://doi.org/10.1021/acsbiomaterials.2c01106
Autor:
Maximilian Scherger, Yannick A. Pilger, Judith Stickdorn, Patric Komforth, Sascha Schmitt, Kaloian Koynov, Hans Joachim Räder, Lutz Nuhn
Publikováno v:
Biomacromolecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec811ac5c74f33cfe18c74c811ac551
https://hdl.handle.net/21.11116/0000-000D-31B5-F21.11116/0000-000D-31B3-1
https://hdl.handle.net/21.11116/0000-000D-31B5-F21.11116/0000-000D-31B3-1
Autor:
Kübra Kaygisiz, Tanja Weil, Franz J. Mayer, Hans Joachim Räder, Christopher V. Synatschke, Adriana Maria Ender
Publikováno v:
ACS Biomaterials Science & Engineering
Gradients of bioactive molecules play a crucial role in various biological processes like vascularization, tissue regeneration, or cell migration. To study these complex biological systems, it is necessary to control the concentration of bioactive mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dada6817485669381bb55d3672dd460
https://doi.org/10.1021/acsbiomaterials.1c00889
https://doi.org/10.1021/acsbiomaterials.1c00889
Autor:
Kübra Kaygisiz, Adriana M. Ender, Jasmina Gačanin, L. Alix Kaczmarek, Dimitrios A. Koutsouras, Abin N. Nalakath, Pia Winterwerber, Franz J. Mayer, Hans‐Joachim Räder, Tomasz Marszalek, Paul W. M. Blom, Christopher V. Synatschke, Tanja Weil
Publikováno v:
Macromolecular Bioscience
Amyloid-like fibrils are a special class of self-assembling peptides that emerge as a promising nanomaterial with rich bioactivity for applications such as cell adhesion and growth. Unlike the extracellular matrix, the intrinsically stable amyloid-li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::678a3ecaa3cfe1f1454a62ac82a9d79f
https://pubmed.ncbi.nlm.nih.gov/36281903
https://pubmed.ncbi.nlm.nih.gov/36281903
Autor:
Annika Wagner, Sascha Jung, Natalie Fuchs, Philipp Klein, Ute Distler, Jochen Klein, Bernd Engels, Ute A. Hellmich, Stefan Tenzer, Fabian Barthels, Hans Joachim Räder, Patrick Johe, Waldemar Waigel, Tri Yuliani, Erika Diehl, Till Opatz, Collin Zimmer, Robert A. Zimmermann, Christian Kersten, Tanja Schirmeister, Jessica Meyr
Publikováno v:
Journal of Medicinal Chemistry. 64:12322-12358
Rhodesain is a major cysteine protease of Trypanosoma brucei rhodesiense, a pathogen causing Human African Trypanosomiasis, and a validated drug target. Recently, we reported the development of α-halovinylsulfones as a new class of covalent reversib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77d1b8e0a10409b4d2df95e00d985a0
https://doi.org/10.1021/acs.jmedchem.1c01002
https://doi.org/10.1021/acs.jmedchem.1c01002
Autor:
Christian Czysch, Carolina Medina‐Montano, Zifu Zhong, Alexander Fuchs, Judith Stickdorn, Pia Winterwerber, Sascha Schmitt, Kim Deswarte, Marco Raabe, Maximilian Scherger, Francis Combes, Jana De Vrieze, Sabah Kasmi, Niek N. Sandners, Stefan Lienenklaus, Kaloian Koynov, Hans‐Joachim Räder, Bart N. Lambrecht, Sunil A. David, Matthias Bros, Hansjörg Schild, Stephan Grabbe, Bruno G. De Geest, Lutz Nuhn
Publikováno v:
Advanced Functional Materials, 32(35):2203490. Wiley-VCH
Advanced Functional Materials
Advanced Functional Materials
The development of controlled biodegradable materials is of fundamental importance in immunodrug delivery to spatiotemporally controlled immune stimulation but avoid systemic inflammatory side effects. Based on this, polycarbonate nanogels are develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5acfb5007876972a84ea63a6bb0c2a2e
https://pure.eur.nl/en/publications/c2730e7e-773c-40fe-a341-123d74664982
https://pure.eur.nl/en/publications/c2730e7e-773c-40fe-a341-123d74664982