Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Hans J. Geissler"'
Autor:
Jonathan Baumgarth, Wilhelm Bloch, Christain Acksteiner, Markus Flesch, Roman Pfister, Kenneth B. Margulies, Hans J. Geissler, Volker Burst, Steven R. Houser
Publikováno v:
Basic Research in Cardiology. 102:257-264
Integrins play a pivotal role in cardiomyocyte survival and function, with integrin loss leading to myocyte apoptosis and heart failure. The aim of this study was to characterize whether regulation of integrins may contribute to cardiac remodeling in
Autor:
Uwe Mehlhorn, A. Antonyan, Klaus Addicks, Uwe M. Fischer, Wilhelm Bloch, Andreas Krahwinkel, Saskia Foerster, Hans J. Geissler, Axel Kroener
Publikováno v:
The Annals of Thoracic Surgery. 82:1742-1746
Previous investigations suggested apoptosis as a contributing factor to early failure of allograft heart valves. As myocardial apoptosis may be induced by nitric oxide (NO) release, this study investigated NO synthase [NOS-III] activation and apoptos
Autor:
Oliver Mehler, Ferdinand Kuhn-Régnier, Jürgen H. Fischer, Aurelia J Lercher, Ernst Rainer de Vivie, Hans J. Geissler, Uwe Mehlhorn
Publikováno v:
Artificial Organs. 28:102-108
Objective: Device supported beating heart surgery has been advocated to extend patient selection criteria for off-pump surgery. This article reports the initial experimental and clinical results with a novel paracardial right ventricular support devi
Autor:
Hans J. Geissler, JH Fischer, Uwe Mehlhorn, Uwe M. Fischer, Ulrike Stock, Wilhelm Bloch, Jerry Easo, Oliver Klass
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 23:984-990
OBJECTIVE Myocardial ischemia-reperfusion is associated with free radical-mediated injury and may be involved in cardiac apoptosis. The purpose of our study was to investigate (1) if cardioplegia-induced ischemia-reperfusion initiates cardiac apoptos
Autor:
R. David Warters, Uwe M. Fischer, Hans J. Geissler, Steven J. Allen, Uwe Mehlhorn, Wilko K Weissenberger
Publikováno v:
Perfusion. 17:401-406
Objective: Cardiac surgery on cardiopulmonary bypass (CPB) is associated with postoperative renal dysfunction and up to 4% of patients with normal preoperative renal function develop acute renal failure (ARF) requiring dialysis. According to recent i
Autor:
Hans J. Geissler
Publikováno v:
The Annals of thoracic surgery. 99(4)
Autor:
Hans J. Geissler, Uwe Mehlhorn
Publikováno v:
Multimedia manual of cardiothoracic surgery : MMCTS. 2006(109)
Cold crystalloid cardioplegia is clinically used since the mid-1960s. It is currently applied in adult and pediatric cardiac surgery patients and remains the preferred method of myocardial protection for many cardiac surgeons. This chapter gives a br
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 20:1220-1230
Fluid accumulation in the cardiac interstitium or myocardial edema is a common manifestation of many clinical states. Specifically, cardiac surgery includes various interventions and pathophysiological conditions that cause or worsen myocardial edema
Autor:
Glen A. Laine, L. Maximilian Buja, Uwe Mehlhorn, Steven J. Allen, Hans J. Geissler, Karen L. Davis, Michael L. Brennan
Publikováno v:
The Annals of Thoracic Surgery. 72:1964-1969
Infarct size can be reduced by beta-blockade in acute myocardial ischemia. However it is unknown whether myocardial salvage is still effective when beta-blockade is limited to reperfusion.After initiation of cardiopulmonary bypass, 20 dogs were submi
Autor:
Glen A. Laine, Hans J. Geissler, Uwe Mehlhorn, Steven J. Allen, Michael L. Brennan, Kenneth L. Davis
Publikováno v:
Microcirculation. 7:269-280
Objective:The mechanism by which chronic myocardial edema causes cardiac dysfunction is poorly understood. We hypothesized that myocardial edema triggers cardiac fibrosis development resulting in cardiac dysfunction. Since collagen is the most abunda