Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Hans Jürgen Stark"'
Autor:
Julia Sieber‐Frank, Hans‐Jürgen Stark, Simon Kalteis, Elena‐Sophie Prigge, Richard Köhler, Carolin Andresen, Thomas Henkel, Georg Casari, Tobias Schubert, Wolfgang Fischl, Min Li‐Weber, Peter H. Krammer, Magnus vonKnebel Doeberitz, Jürgen Kopitz, Matthias Kloor, Aysel Ahadova
Publikováno v:
Cancer Medicine, Vol 10, Iss 19, Pp 6807-6822 (2021)
Abstract Rocaglates are natural compounds that have been extensively studied for their ability to inhibit translation initiation. Rocaglates represent promising drug candidates for tumor treatment due to their growth‐inhibitory effects on neoplasti
Externí odkaz:
https://doaj.org/article/c86b61b3c2344cd3b3e599e1e49f65ee
Autor:
Marius Tham, Hans-Jürgen Stark, Anna Jauch, Catherine Harwood, Elizabeth Pavez Lorie, Petra Boukamp
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
The BRAF inhibitor vemurafenib, approved for treating patients with BRAF V600E-mutant and unresectable or metastatic melanomas, rapidly induces cutaneous adverse events, including hyperkeratotic skin lesions and cutaneous squamous cell carcinomas (cS
Externí odkaz:
https://doaj.org/article/3784958c0e834885a89b197f06f6609b
Autor:
Lionel Larribère, Marta Galach, Daniel Novak, Karla Arévalo, Hans Christian Volz, Hans-Jürgen Stark, Petra Boukamp, Michael Boutros, Jochen Utikal
Publikováno v:
Stem Cell Reports, Vol 9, Iss 4, Pp 1234-1245 (2017)
Molecular mechanisms responsible for the development of human skin epithelial cells are incompletely understood. As a consequence, the efficiency to establish a pure skin epithelial cell population from human induced pluripotent stem cells (hiPSCs) r
Externí odkaz:
https://doaj.org/article/684d11bbfff949e0919477c0864711bc
Autor:
Richard Köhler, Aysel Ahadova, Simon Kalteis, Thomas Henkel, Peter H. Krammer, Hans-Jürgen Stark, Tobias Schubert, Magnus von Knebel Doeberitz, Wolfgang Fischl, Matthias Kloor, Elena-Sophie Prigge, Georg Casari, Carolin Andresen, Min Li-Weber, Julia Sieber-Frank, Jürgen Kopitz
Publikováno v:
Cancer Medicine, Vol 10, Iss 19, Pp 6807-6822 (2021)
Cancer Medicine
Cancer Medicine
Rocaglates are natural compounds that have been extensively studied for their ability to inhibit translation initiation. Rocaglates represent promising drug candidates for tumor treatment due to their growth‐inhibitory effects on neoplastic cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127d94e2c661d08693eb5f7716dbc11f
https://doaj.org/article/c86b61b3c2344cd3b3e599e1e49f65ee
https://doaj.org/article/c86b61b3c2344cd3b3e599e1e49f65ee
Autor:
Wolfgang Kaisers, Petra Boukamp, Hans-Jürgen Stark, Holger Schwender, Julia Tigges, Jean Krutmann, Heiner Schaal
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0175657 (2017)
Ageing, the progressive functional decline of virtually all tissues, affects numerous living organisms. Main phenotypic alterations of human skin during the ageing process include reduced skin thickness and elasticity which are related to extracellul
Externí odkaz:
https://doaj.org/article/dafb7b89d4054640ba4ecac395aec156
Autor:
Pauline L. Pfuderer, Florian Seidler, Magnus von Knebel Doeberitz, Ian M. Frayling, Matthias Kloor, Alexej Ballhausen, Niels Grabe, Aysel Ahadova, Ann Ager, Hans Jürgen Stark
Publikováno v:
British Journal of Cancer
Background Microsatellite-unstable (MSI) tumours show a high load of mutational neoantigens, as a consequence of DNA mismatch repair deficiency. Consequently, MSI tumours commonly present with dense immune infiltration and develop immune evasion mech
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ee1e8cb78e60351ee4696ff98550173
https://doi.org/10.1038/s41416-019-0514-6
https://doi.org/10.1038/s41416-019-0514-6
Autor:
Michael Boutros, Daniel Novak, Hans C. Volz, Jochen Utikal, Lionel Larribère, Petra Boukamp, Karla Arévalo, Marta Galach, Hans Jürgen Stark
Publikováno v:
Stem Cell Reports, Vol 9, Iss 4, Pp 1234-1245 (2017)
Stem Cell Reports
Stem Cell Reports
Summary Molecular mechanisms responsible for the development of human skin epithelial cells are incompletely understood. As a consequence, the efficiency to establish a pure skin epithelial cell population from human induced pluripotent stem cells (h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda9c652bd60c4f9fe1399c41a3ef59a
https://doi.org/10.1016/j.stemcr.2017.08.023
https://doi.org/10.1016/j.stemcr.2017.08.023
Autor:
Annette Affolter, Philippe A. Federspil, P. K. Plinkert, Hans-Jürgen Stark, Elena-Sophie Prigge, Jochen Hess, Niels Grabe, Natalia Koerich Laureano, Magnus von Knebel Doeberitz, Julia Thierauf, Dominik Horn, Luca Engelmann, Kolja Freier
Publikováno v:
Cancer Research. 80:336-336
Background. Head and neck squamous cell carcinomas (HNSCC) are histologically and molecularly heterogeneous tumors and frequently develop resistance mechanisms against treatment. Reliable patient-derived 3D tumor models are urgently needed to further
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2088d599914a2d6360a309552789ad0d
https://doi.org/10.1158/1538-7445.am2020-336
https://doi.org/10.1158/1538-7445.am2020-336
Nonmelanoma skin cancer is the most prevalent cancer worldwide, and a number of cases are steadily increasing. The incidence of skin squamous cell carcinoma, which is the second most frequent tumor in this group of tumors, is markedly increasing in i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50e2c84a81db6a3d92b577b72825b8e2
https://doi.org/10.1016/b978-0-12-810545-0.00007-3
https://doi.org/10.1016/b978-0-12-810545-0.00007-3
Autor:
Julia Tigges, Holger Schwender, Petra Boukamp, Wolfgang Kaisers, Jean Krutmann, Hans Jürgen Stark, Heiner Schaal
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0175657 (2017)
PLoS ONE
PLoS ONE
Ageing, the progressive functional decline of virtually all tissues, affects numerous living organisms. Main phenotypic alterations of human skin during the ageing process include reduced skin thickness and elasticity which are related to extracellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1676975767f1d70ed0cb2987ed49df75
http://europepmc.org/articles/PMC5419556?pdf=render
http://europepmc.org/articles/PMC5419556?pdf=render