Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Hans Jürgen Gruber"'
Autor:
Julia M. Kröpfl, Fernando G. Beltrami, Hans‐Jürgen Gruber, Arno Schmidt‐Trucksäss, Thomas Dieterle, Christina M. Spengler
Publikováno v:
Experimental Physiology, Vol 108, Iss 10, Pp 1259-1267 (2023)
Abstract Long‐term, intense endurance exercise training can occasionally induce endothelial micro‐damage and cardiac fibrosis. The underlying mechanisms are incompletely understood. Twenty healthy, well‐trained male participants (10 runners and
Externí odkaz:
https://doaj.org/article/6120ad9c4a4c437eafeb20c3a939e719
Autor:
Maria Donatella Semeraro, Antonio Paolo Beltrami, Feras Kharrat, Gunter Almer, Simon Sedej, Wilfried Renner, Hans-Jürgen Gruber, Francesco Curcio, Markus Herrmann
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2023)
IntroductionHypercaloric nutrition and physical inactivity cause obesity, a potential driver of myocardial apoptosis and senescence that may accelerate cardiac aging. Although physical activity reduces mortality, its impact on myocardial aging is ins
Externí odkaz:
https://doaj.org/article/015536fe81c94399afd9510efea2371f
Publikováno v:
Frontiers in Physiology, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/1714698492a440f5ad932fe64af62dab
Autor:
Gunter Almer, Maria Donatella Semeraro, Andreas Meinitzer, Dietmar Enko, Giovanny Rodriguez Blanco, Birgit Gall, Angela Horvath, Christine Moissl-Eichinger, Holger Till, Hans-Jürgen Gruber, Markus Herrmann
Publikováno v:
Nutrition and Healthy Aging. :1-14
BACKGROUD: Trimethylamine oxide (TMAO) represents a gut metabolite and it's physiological concentration is proposed to be influenced by the abundance of precursor trimethylamine (TMA)-producing microbiota in the gut. OBJECTIVE: Lifestyle factors, suc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::969cb1f9971a39be3224679b6285c0ab
https://doi.org/10.3233/nha-220198
https://doi.org/10.3233/nha-220198
Publikováno v:
Cells, Vol 11, Iss 10, p 1605 (2022)
(1) Obesity and exercise are believed to modify age-related telomere shortening by regulating telomerase and shelterins. Existing studies are inconsistent and limited to peripheral blood mononuclear cells (PBMCs) and selected solid tissues. (2) Femal
Externí odkaz:
https://doaj.org/article/6247646420d44969bce18bb54bc3ae4c
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Exercise is known to acutely and transiently mobilize precursor cells to the peripheral blood. To date, the underlying mechanisms have not yet been fully elucidated and we hypothesized that exercise-induced oxidative stress could be a mobilizing agen
Externí odkaz:
https://doaj.org/article/eb44f909e6994d06b82711352908bcee
Autor:
Julia M. Kröpfl, Fernando G. Beltrami, Hans-Jürgen Gruber, Ingeborg Stelzer, Christina M. Spengler
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
It has been proposed that exercise-induced systemic oxidative stress increases circulating hematopoietic stem and progenitor cell (HPC) number in active participants, while HPC clonogenicity is reduced post-exercise. However, HPCs could be protected
Externí odkaz:
https://doaj.org/article/4c66c543eef74aa1940e9451794f0ec7
Autor:
Julia M. Kröpfl, Tobias Kammerer, Valentina Faihs, Hans-Jürgen Gruber, Jan Stutz, Markus Rehm, Ingeborg Stelzer, Simon T. Schäfer, Christina M. Spengler
Publikováno v:
Frontiers in Physiology, Vol 10 (2020)
Travel of unacclimatized subjects to a high altitude has been growing in popularity. Changes in endothelial shedding [circulating endothelial cells (ECs)] and hematopoietic stem and progenitor cells (CPCs) during physical exercise in hypobaric hypoxi
Externí odkaz:
https://doaj.org/article/7f83e4d33d2046c3865f2b5ec9747ea8
Publikováno v:
Biomedicines, Vol 9, Iss 10, p 1335 (2021)
Telomeres are at the non-coding ends of linear chromosomes. Through a complex 3-dimensional structure, they protect the coding DNA and ensure appropriate separation of chromosomes. Aging is characterized by a progressive shortening of telomeres, whic
Externí odkaz:
https://doaj.org/article/31b02892079643489e94bb9f20999f6e
Autor:
Tobias Niedrist, Sabine Pailer, Renate Jahrbacher, Hans-Jürgen Gruber, Markus Herrmann, Wilfried Renner
Publikováno v:
Journal of Laboratory Medicine. 46:179-185
Objectives Exercise induces telomerase activity and regulates shelterin expression. These effects are believed to preserve telomeres. However, the impact of exercise intensity on telomerase and shelterins has not been studied systematically. This pil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53b80ebbfc306ed595c697d92949288c
https://doi.org/10.1515/labmed-2022-0054
https://doi.org/10.1515/labmed-2022-0054