Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Hans Henning Brewitz"'
Autor:
Hans Henning Brewitz, Hyon-Xhi Tan, Margi I. Butler, Russell T. M. Poulter, Torsten Kleffmann, Thomas N. G. Handley, Joel D. A. Tyndall, Malcolm T. Rutledge, Sigurd M. Wilbanks
Publikováno v:
New Zealand Journal of Botany. 58:358-377
A system based on cyanobacterial split inteins, SICLOPPs (Split Intein Circular Ligation of Proteins and Peptides), has been used to synthesise a small natively cyclic plant protein, kalata B1, and cyclised versions of the natively linear therapeutic
Autor:
Diana Imhof, Pascal Heimer, Toshinori Hoshi, Matthias Westerhausen, Guido Gessner, Stefan H. Heinemann, Nirakar Sahoo, Ralf Mede, Gianna Hirth, Hans Henning Brewitz, Roland Schönherr, Sandip M. Swain
Publikováno v:
European Journal of Pharmacology. 815:33-41
Although toxic when inhaled in high concentrations, the gas carbon monoxide (CO) is endogenously produced in mammals, and various beneficial effects are reported. For potential medicinal applications and studying the molecular processes underlying th
Publikováno v:
Bioscience Reports
Deviant levels of available heme and related molecules can result from pathological situations such as impaired heme biosynthesis or increased hemolysis as a consequence of vascular trauma or bacterial infections. Heme-related biological processes ar
Autor:
Sandra Peherstorfer, Hans Henning Brewitz, Ajay Abisheck Paul George, Diana Imhof, Amelie Wißbrock, Jana Maria Adam, Lutz Schmitt
Publikováno v:
Biochimica et biophysica acta. General subjects. 1862(9)
Background Tight regulation of heme homeostasis is a critical mechanism in pathogenic bacteria since heme functions as iron source and prosthetic group, but is also toxic at elevated concentrations. Hemolysin-activating lysine-acyltransferase (HlyC)
Autor:
Jürgen Popp, Diana Imhof, Oliver Ohlenschläger, Ute Neugebauer, Kerstin Galler, Nishit Goradia, Toni Kühl, Hans Henning Brewitz
Publikováno v:
ChemBioChem. 16:2216-2224
The importance of heme as a transient regulatory molecule has become a major focus in biochemical research. However, detailed information about the molecular basis of transient heme-protein interactions is still missing. We report an in-depth structu
Autor:
Guido, Gessner, Nirakar, Sahoo, Sandip M, Swain, Gianna, Hirth, Roland, Schönherr, Ralf, Mede, Matthias, Westerhausen, Hans Henning, Brewitz, Pascal, Heimer, Diana, Imhof, Toshinori, Hoshi, Stefan H, Heinemann
Publikováno v:
European journal of pharmacology. 815
Although toxic when inhaled in high concentrations, the gas carbon monoxide (CO) is endogenously produced in mammals, and various beneficial effects are reported. For potential medicinal applications and studying the molecular processes underlying th
Autor:
Diana Imhof, Hans Henning Brewitz, Toni Kühl, Oliver Ohlenschläger, Gregor Hagelueken, Nishit Goradia, Kerstin Galler, Erik Schubert, Jürgen Popp, Olav Schiemann, Ute Neugebauer, Benjamin Franz Syllwasschy
Publikováno v:
Biochimica et biophysica acta. 1860(6)
Background The occurrence of free organismal heme can either contribute to serious diseases or beneficially regulate important physiological processes. Research on transient binding to heme-regulatory motifs (HRMs) in proteins resulted in the discove
Autor:
Diana Imhof, Toni Kühl, Nishit Goradia, Hans Henning Brewitz, Amelie Wißbrock, Oliver Ohlenschläger
Publikováno v:
ECS Meeting Abstracts. :941-941
The role and action of heme as a regulatory effector of proteins came more and more into the focus of biochemical research aiming at a complete understanding of this molecule’s function in the organism apart from its well-investigated embedment in