Zobrazeno 1 - 10
of 342
pro vyhledávání: '"Hans Hengartner"'
Autor:
Karl S Lang, Ahmed N Hegazy, Philipp A Lang, Bruno Eschli, Max Löhning, Hans Hengartner, Rolf M Zinkernagel, Mike Recher
Publikováno v:
PLoS ONE, Vol 2, Iss 11, p e1162 (2007)
BACKGROUND: Cooperation of CD4+ T helper cells with specific B cells is crucial for protective vaccination against pathogens by inducing long-lived neutralizing antibody responses. During infection with persistence-prone viruses, prolonged virus repl
Externí odkaz:
https://doaj.org/article/524c80c646cf44d89bd069f2d6e6fb46
Publikováno v:
Cytolytic Lymphocytes and Complement: Effectors of the Immune System ISBN: 9781351071291
Cloned cell lines with high cytotoxic activity have become available. It has become possible to grow large numbers of homogeneous populations of cells for biochemical and biophysical studies. This chapter reviews the cytolytic properties associated w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23f61eeff2c056a16483c8d6a98af3ce
https://doi.org/10.1201/9781351071291-3
https://doi.org/10.1201/9781351071291-3
Very little is known about the conformational properties of the MHC molecules that are able to signal positive selection of a given TCR. To try to understand these parameters and to determine whether these requirements are shared with interactions du
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea0f2627c6aaa702412ff114061fd2f
http://doc.rero.ch/record/298042/files/5-2-131.pdf
http://doc.rero.ch/record/298042/files/5-2-131.pdf
Autor:
Karl S. Lang, Aleksandra A. Pandyra, Hans Hengartner, Namir Shaabani, Haifeng C. Xu, Nadine Honke, Isaac S. Harris, Vitaly I. Pozdeev, Dieter Häussinger, S Kumar Maney, Melanie Grusdat, R M Zinkernagel, David R. McIlwain, Elisabeth Lang, Bernhard Odermatt, Pamela S. Ohashi, Mike Recher, Philipp A. Lang, Tak W. Mak, Dirk Brenner
Publikováno v:
Cell Death and Differentiation
Cluster of differentiation (CD)8(+) T cells are like a double edged sword during chronic viral infections because they not only promote virus elimination but also induce virus-mediated immunopathology. Elevated levels of reactive oxygen species (ROS)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b29565bda3600fd64d75fc33ec09a50b
https://doi.org/10.1038/cdd.2012.167
https://doi.org/10.1038/cdd.2012.167
Infection of adult mice with lymphocytic choriomeningitis virus (LCMV), a non-cytopathic segmented RNA virus, leads initially to generalized infection, followed by clearance and subsequent life-long immunity. Indirect evidence has suggested that vira
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b9b5e9284142731d636510a48be21e
https://doi.org/10.1038/36876
https://doi.org/10.1038/36876
Antigens normally induce an immunoglobulin (Ig)G response which stays at an elevated level for several weeks or months, constituting an important part of the immunological memory. This study investigated factors influencing the level of neutralizing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::996aecd1079484ee42336ab690bb03af
https://ora.ox.ac.uk/objects/uuid:2f98f363-2864-4dfd-981f-e6af77cf58d6
https://ora.ox.ac.uk/objects/uuid:2f98f363-2864-4dfd-981f-e6af77cf58d6
To analyze the critical parameters for effective antiviral cytotoxic T lymphocyte (CTL) activity in vivo, control of lymphocytic choriomeningitis virus (LCMV) infection in the spleen was studied after adoptive transfer of different spleen cell popula
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::309067adb19d69893a9ddfd5ef422bec
https://ora.ox.ac.uk/objects/uuid:23ef33f6-6aa9-48b9-bb04-aeb7500ddc87
https://ora.ox.ac.uk/objects/uuid:23ef33f6-6aa9-48b9-bb04-aeb7500ddc87
Autor:
K A Campbell, Tadamitsu Kishimoto, H Kikutani, Hans Hengartner, R M Zinkernagel, Annette Oxenius, C R Maliszewski, Martin F. Bachmann
Publikováno v:
The Journal of Experimental Medicine
CD40-CD40 ligand (CD40L) interaction is required for the generation of antibody responses to T-dependent antigens as well as for the development of germinal centers and memory B cells. The role of the CD40-CD40L interaction in the induction of antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71985f1b1feba7916de25407dab889a
https://doi.org/10.1084/jem.183.5.2209
https://doi.org/10.1084/jem.183.5.2209
Autor:
Stephan Oehen, Martin F. Bachmann, Rolf M. Zinkernagel, Thomas M. Kündig, Hanspeter Pirchet, Hans Hengartner
▪ Abstract Immunological memory is a hallmark of the immune system. Evolution can teach us which effector arms of immunological memory are biologically relevant against which virus. Antibodies appear to be the critical protective mechanism against
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263119b5a7af20c401c2b8f869d262d3
https://ora.ox.ac.uk/objects/uuid:6941f586-ca35-4122-8088-fa6d2517d5c0
https://ora.ox.ac.uk/objects/uuid:6941f586-ca35-4122-8088-fa6d2517d5c0
Publikováno v:
Forum Médical Suisse ‒ Swiss Medical Forum. 16
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4335de6df618b022e760355d7046e4e1
https://doi.org/10.4414/fms.2016.02668
https://doi.org/10.4414/fms.2016.02668