Zobrazeno 1 - 10
of 268
pro vyhledávání: '"Hans H. Cheng"'
Autor:
Edward S. Rice, Antton Alberdi, James Alfieri, Giridhar Athrey, Jennifer R. Balacco, Philippe Bardou, Heath Blackmon, Mathieu Charles, Hans H. Cheng, Olivier Fedrigo, Steven R. Fiddaman, Giulio Formenti, Laurent A. F. Frantz, M. Thomas P. Gilbert, Cari J. Hearn, Erich D. Jarvis, Christophe Klopp, Sofia Marcos, Andrew S. Mason, Deborah Velez-Irizarry, Luohao Xu, Wesley C. Warren
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-17 (2023)
Abstract Background The red junglefowl, the wild outgroup of domestic chickens, has historically served as a reference for genomic studies of domestic chickens. These studies have provided insight into the etiology of traits of commercial importance.
Externí odkaz:
https://doaj.org/article/ec4f115e8cb94416b00a87c078953189
Autor:
Wesley C. Warren, Edward S. Rice, Ashley Meyer, Cari J. Hearn, Alec Steep, Henry D. Hunt, Melissa S. Monson, Susan J. Lamont, Hans H. Cheng
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Genetically resistant or susceptible chickens to Marek’s disease (MD) have been widely used models to identify the molecular determinants of these phenotypes. However, these prior studies lacked the basic identification and understanding o
Externí odkaz:
https://doaj.org/article/31c8b6b6fe764f95a8893853ec7ad337
Autor:
Taejoong Kim, Cari J. Hearn, Jody Mays, Deborah Velez-Irizarry, Sanjay M. Reddy, Stephen J. Spatz, Hans H. Cheng, John R. Dunn
Publikováno v:
Viruses, Vol 15, Iss 11, p 2263 (2023)
Marek’s disease (MD) is a highly infectious lymphoproliferative disease in chickens with a significant economic impact. Mardivirus gallidalpha 2, also known as Marek’s disease virus (MDV), is the causative pathogen and has been categorized based
Externí odkaz:
https://doaj.org/article/f5d8fa81c9184324b90272b298de58e6
Autor:
Dailu Guan, Michelle M. Halstead, Alma D. Islas-Trejo, Daniel E. Goszczynski, Hans H. Cheng, Pablo J. Ross, Huaijun Zhou
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
To identify and annotate transcript isoforms in the chicken genome, we generated Nanopore long-read sequencing data from 68 samples that encompassed 19 diverse tissues collected from experimental adult male and female White Leghorn chickens. More tha
Externí odkaz:
https://doaj.org/article/915560d8bc5a44b6a2e37a48342c5262
Autor:
Colin Kern, Ying Wang, Xiaoqin Xu, Zhangyuan Pan, Michelle Halstead, Ganrea Chanthavixay, Perot Saelao, Susan Waters, Ruidong Xiang, Amanda Chamberlain, Ian Korf, Mary E. Delany, Hans H. Cheng, Juan F. Medrano, Alison L. Van Eenennaam, Chris K. Tuggle, Catherine Ernst, Paul Flicek, Gerald Quon, Pablo Ross, Huaijun Zhou
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
In order to interpret non-coding variants, information about regulatory elements in the genome is essential. Here, the authors annotate regulatory elements in chicken, pig and cattle, and characterize conservation of these elements between species.
Externí odkaz:
https://doaj.org/article/2a0d0f16ec8a4f52b116348aae893cf0
Autor:
Cari J. Hearn, Hans H. Cheng
Publikováno v:
Viruses, Vol 15, Iss 3, p 607 (2023)
Marek’s disease (MD) is a lymphoproliferative disease of chickens induced by Marek’s disease virus (MDV), an oncogenic α-herpesvirus. MDV has increased in virulence, prompting continued efforts in both improved vaccines and enhanced genetic resi
Externí odkaz:
https://doaj.org/article/93bc1371715a41aca333e7e92943f2c8
Autor:
Hao Bai, Yanghua He, Yi Ding, Qin Chu, Ling Lian, Eliyahu M. Heifetz, Ning Yang, Hans H. Cheng, Huanmin Zhang, Jilan Chen, Jiuzhou Song
Publikováno v:
BMC Genetics, Vol 21, Iss 1, Pp 1-12 (2020)
Abstract Background Marek’s disease (MD) is a highly neoplastic disease primarily affecting chickens, and remains as a chronic infectious disease that threatens the poultry industry. Copy number variation (CNV) has been examined in many species and
Externí odkaz:
https://doaj.org/article/8b3b0f850bb34837baa9037746577d56
Autor:
Amanda Jane Chamberlain, Hans H. Cheng, Elisabetta Giuffra, Christa Kuehn, Christopher K. Tuggle, Huaijun Zhou
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Externí odkaz:
https://doaj.org/article/8738c45777cb449885e3b564ce94de28
Autor:
Alec Steep, Evin Hildebrandt, Hongen Xu, Cari Hearn, Dmitrij Frishman, Masahiro Niikura, John R. Dunn, Taejoong Kim, Steven J. Conrad, William M. Muir, Hans H. Cheng
Publikováno v:
Microorganisms, Vol 10, Iss 2, p 401 (2022)
Marek’s disease virus (MDV) is the causative agent for Marek’s disease (MD), which is characterized by T-cell lymphomas in chickens. While the viral Meq oncogene is necessary for transformation, it is insufficient, as not every bird infected with
Externí odkaz:
https://doaj.org/article/e65073d0d4f54e05a45541ca52affc0e
Autor:
Richard I Bailey, Hans H Cheng, Margo Chase-Topping, Jody K Mays, Osvaldo Anacleto, John R Dunn, Andrea Doeschl-Wilson
Publikováno v:
PLoS Biology, Vol 18, Iss 3, p e3000619 (2020)
Many livestock and human vaccines are leaky because they block symptoms but do not prevent infection or onward transmission. This leakiness is concerning because it increases vaccination coverage required to prevent disease spread and can promote evo
Externí odkaz:
https://doaj.org/article/4b30503beac941278623d6bc6c857eab