Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Hans Graffner"'
Autor:
Kjell-Arne Ung, Richard N. Appleby, P-G Gillberg, Hans Graffner, Magnus Simren, Antal Bajor, Jrf Walters
Publikováno v:
United European Gastroenterology Journal. 5:380-388
Background: Primary bile acid diarrhoea (BAD) is associated with increased bile acid synthesis and low fibroblast growth factor 19 (FGF19). Bile acid sequestrants are used as therapy, but are poorly tolerated and may exacerbate FGF19 deficiency. Aim:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b26d04650d4dca8e433d97c850da26b2
https://doi.org/10.1177/2050640616662432
https://doi.org/10.1177/2050640616662432
Publikováno v:
The American Journal of Gastroenterology
OBJECTIVES: A3309 is a minimally absorbed ileal bile acid (BA) transporter (IBAT) inhibitor. We conducted an 8-week, multicenter, randomized, double-blind, placebo-controlled, parallel group, phase IIb study, which evaluated A3309 in patients with ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2b35fcd592861a41895727db564c583
https://doi.org/10.1038/ajg.2011.162
https://doi.org/10.1038/ajg.2011.162
Publikováno v:
Scandinavian Journal of Haematology. 28:369-375
Of 377 patients with chronic duodenal ulcer undergoing highly selective vagotomy, 13 were splenectomized peroperatively because of capsular tear. 12 of these patients were alive at the time of the subsequent investigation and each was matched with a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e9d424d4fe7d7cbbba12b2def1e2f1
https://doi.org/10.1111/j.1600-0609.1982.tb00541.x
https://doi.org/10.1111/j.1600-0609.1982.tb00541.x
Publikováno v:
BMC Cardiovascular Disorders
Elobixibat is a minimally absorbed ileal bile acid (BA) transporter (IBAT) inhibitor in development against chronic constipation (CC) and constipation-predominant Irritable Bowel Syndrome (IBS-C). CC is associated with an increased risk for cardiovas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fda38f849b277bab00d7b37bf612cd39
http://europepmc.org/articles/PMC4511433
http://europepmc.org/articles/PMC4511433
Autor:
Anna, Baghdasaryan, Claudia D, Fuchs, Christoph H, Österreicher, Ursula J, Lemberger, Emina, Halilbasic, Ingrid, Påhlman, Hans, Graffner, Elisabeth, Krones, Peter, Fickert, Annika, Wahlström, Marcus, Ståhlman, Gustav, Paumgartner, Hanns-Ulrich, Marschall, Michael, Trauner
Publikováno v:
Journal of hepatology. 64(3)
Approximately 95% of bile acids (BAs) excreted into bile are reabsorbed in the gut and circulate back to the liver for further biliary secretion. Therefore, pharmacological inhibition of the ileal apical sodium-dependent BA transporter (ASBT/SLC10A2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fbe0f52da439664cd4831cfba5a936a4
https://pubmed.ncbi.nlm.nih.gov/26708144
https://pubmed.ncbi.nlm.nih.gov/26708144
Autor:
Manfred Stolte, Jukka Ronkainen, Nicholas J. Talley, Lars Agréus, Pertti Aro, Hans Graffner, Michael Vieth, E. Bolling-Sternevald, Sven-Erik Johansson, Tore Lind, Lars Engstrand, Tom Storskrubb
Publikováno v:
Scandinavian Journal of Gastroenterology. 40:275-285
Objective. Gastroesophageal reflux disease has been reported to be a common burden on health-care resources in the Western world, but its manifestations in the general population are as yet unclear. The aim of this study was to estimate the prevalenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::48eaa325cfb2170853f079d6a53311d1
https://doi.org/10.1080/00365520510011579
https://doi.org/10.1080/00365520510011579
Publikováno v:
Alimentary Pharmacology & Therapeutics. 20:751-760
Summary Background : Cross-sectional studies indicate that gastro-oesophageal reflux disease symptoms have a prevalence of 10–20% in Western countries and are associated with obesity, smoking, oesophagitis, chest pain and respiratory disease. Aim :
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9bbdeea57c7bfde961150253788efa9
https://doi.org/10.1111/j.1365-2036.2004.02169.x
https://doi.org/10.1111/j.1365-2036.2004.02169.x
Autor:
Eran Israeli, Reinhold W. Stockbrügger, Dieter Felsenberg, L Landgraf, G. Bianchi Porro, Allister I. Ferguson, Tore Persson, Erik J. Schoon, Simona Bollani, Hans Graffner, Sverker Ljunghall, Peter R. Mills, G Nygård
Publikováno v:
Alimentary Pharmacology & Therapeutics. 16:1519-1527
Discordance between the degree of osteopenia and the prevalence of spontaneous vertebral fractures in Crohn's disease. Stockbrugger RW, Schoon EJ, Bollani S, Mills PR, Israeli E, Landgraf L, Felsenberg D, Ljunghall S, Nygard G, Persson T, Graffner H,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::869065639bc68bb88397cc0cfc3d3481
https://doi.org/10.1046/j.1365-2036.2002.01317.x
https://doi.org/10.1046/j.1365-2036.2002.01317.x
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 27:295-298
1. Joint pain is a frequent manifestation of Crohn's disease. Budesonide controlled ileal release (CTR) is a predominantly topically acting glucocorticosteroid, which is effective in treating active ileal or ileocaecal Crohn's disease, 2. Therefore,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c4e8c1345f6395e372b67eafd18f608
https://doi.org/10.1046/j.1440-1681.2000.03238.x
https://doi.org/10.1046/j.1440-1681.2000.03238.x
Publikováno v:
Digestive Diseases and Sciences. 45:1648-1652
Smokers show higher rates of peptic ulcer disease (PUD) than nonsmokers, probably due to detrimental effects on the gastric mucosa. Surface-active phospholipids (SPL) are believed to play a key part in gastric cytoprotection. The aim of this study wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::340815b68d76af2f5dc8d80af03ec220
https://doi.org/10.1023/a:1005537716582
https://doi.org/10.1023/a:1005537716582