Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Hans Gfeller"'
Publikováno v:
Toxicological Sciences. 143:319-332
Three in vitro methods for the prediction of the skin sensitization hazard have been validated. However, predicting sensitizer potency is a key requirement for risk assessment. Here, we report a database of 312 chemicals tested in the KeratinoSens™
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad70ef697ff77b45733d13034359c2d7
https://doi.org/10.1093/toxsci/kfu229
https://doi.org/10.1093/toxsci/kfu229
Publikováno v:
Chemical Research in Toxicology. 23:1913-1920
(E)-4-(ethoxymethylene)-2-phenyloxazol-5(4H)-one, commonly referred to as oxazolone, is the most potent skin sensitizer in published databases as determined with the murine local lymph node assay. It has been used very widely in immunological researc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b1e3580327a7e3132493a16172ca4b5
https://doi.org/10.1021/tx1002707
https://doi.org/10.1021/tx1002707
Publikováno v:
Toxicology in Vitro. 21:1220-1226
A key step in the skin sensitization process is the formation of a covalent adduct between the skin sensitizer and endogenous proteins and/or peptides in the skin. A published peptide depletion assay was used to relate the in vitro reactivity of frag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf31b45971861e458733c9d7465a759b
https://doi.org/10.1016/j.tiv.2007.03.016
https://doi.org/10.1016/j.tiv.2007.03.016
Publikováno v:
International Journal of Cosmetic Science. 27:115-122
Axillary odor is known since 50 years to be formed upon the action of Corynebacteria on odorless axilla secretions, but the nature of the bacterial enzymes involved in this process remained a mystery. We identified the known axilla odor determinant 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6eeae94422fbadd6fc6712142d651ab
https://doi.org/10.1111/j.1467-2494.2004.00255.x
https://doi.org/10.1111/j.1467-2494.2004.00255.x
Publikováno v:
Journal of Biological Chemistry. 278:5718-5727
Human axillary odor is known to be formed upon the action of Corynebacteria sp. on odorless axilla secretions. The known axilla odor determinant 3-methyl-2-hexenoic acid was identified in hydrolyzed axilla secretions along with a chemically related c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c25c5c2a8c526ddf2787b8752c4271
https://doi.org/10.1074/jbc.m210142200
https://doi.org/10.1074/jbc.m210142200
Publikováno v:
Environmental sciencetechnology. 48(16)
Bioaccumulation in aquatic species is a critical end point in the regulatory assessment of chemicals. Few measured fish bioconcentration factors (BCFs) are available for fragrance ingredients. Thus, predictive models are often used to estimate their
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab3bb6805c55c5164c8a1ecf809e5db
https://pubmed.ncbi.nlm.nih.gov/25058173
https://pubmed.ncbi.nlm.nih.gov/25058173
Publikováno v:
Biochemical Systematics and Ecology. 25:195-201
The defensive secretion of the ventral glands of both species, Hoplocampa testudinea and H. flava is mainly composed of acetogenins. Major compounds are (E)-2-octenal, (E,Z)- and (E,E)-2,4-decadienal and (E,Z,Z)-2,4,7-decatrienal that was identified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c52da42e39e1677658af797695c83740
https://doi.org/10.1016/s0305-1978(96)00112-3
https://doi.org/10.1016/s0305-1978(96)00112-3
Publikováno v:
Phytochemistry. 42:967-972
The betaine lipids diacylglycerylhydroxymethyltrimethyl-β-alanine (DGTA) and diacylglyceryltrimethylhomoserine (DGTS) can be identified by derivatization of their polar groups. Demethylation, deacylation and silylation of DGTS yields demethyl-deacyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::183a3acd3d9148eee03c3753bd8c024e
https://doi.org/10.1016/0031-9422(96)00055-6
https://doi.org/10.1016/0031-9422(96)00055-6
Publikováno v:
Journal of Plant Physiology. 146:398-404
Summary The phosphoglyceride phosphatidyl- O -[ N (2-hydroxyethyl)glycine] (PHEG) has been isolated from Fucus serratus L. (Fucales, Phaeophyceae) and its structure determined by IR, NMR, MS and chemical data of the intact lipid (formerly called PX),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1edd3bdf001516cf01bc86f438418466
https://doi.org/10.1016/s0176-1617(11)81999-1
https://doi.org/10.1016/s0176-1617(11)81999-1
Publikováno v:
Chemical research in toxicology. 25(10)
Skin sensitizers chemically modify skin proteins rendering them immunogenic. Sensitizing chemicals have been divided into applicability domains according to their suspected reaction mechanism. The widely accepted Schiff base applicability domain cove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d8f8cbe3a71268bd9bd9be7598b6602
https://pubmed.ncbi.nlm.nih.gov/22950880
https://pubmed.ncbi.nlm.nih.gov/22950880