Výsledky vyhledávání - "Hans G. Bone"

Hemodynamic effects of exogenous adrenomedullin in healthy and endotoxemic sheep

Autor: Michael Booke, Fritz Daudel, Henning D. Stubbe, Hans G. Bone, Martin Westphal, Hugo Van Aken, Sebastian Vocke

Publikováno v: Biochemical and Biophysical Research Communications. 296:134-138

Adrenomedullin (AM) is a vasodilatory peptide hormone, playing a key role in the regulation of cardiovascular homeostasis. In view of the circulatory failure in sepsis, it is still debated as to whether the occurrence of vascular hyporeactivity again

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06bc87c0f4303f644bc5577059729fd9
https://doi.org/10.1016/s0006-291x(02)00821-5

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Effects of manganese superoxide dismutase, when given after inhalation injury has been established

Autor: Hans G. Bone, Paul J. Schenarts, Heroiko Sakurai, Lillian D. Traber, Daniel L. Traber

Publikováno v: Critical Care Medicine. 30:856-860

Objectives: To determine whether treatment with manganese superoxide dismutase (MnSOD), given intravenously after inhalation injury has been established, improves oxygenation and lung fluid balance. Design: Randomized, controlled intervention trial.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::483c7f783fa3af495b74ad9e41a3cabb
https://doi.org/10.1097/00003246-200204000-00024

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Thoracic, but Not Lumbar, Epidural Anesthesia Improves Cardiopulmonary Function in Ovine Pulmonary Embolism

Autor: Uli R. Jahn, René Waurick, Jörg Meyer, Christoph Schmidt, Frank Hinder, Hans G. Bone, Michael Booke, Hugo Van Aken

Publikováno v: Anesthesia & Analgesia. 93:1460-1465

UNLABELLED We hypothesized that sympathetic stimulation is the main mechanism contributing to hemodynamic failure in pulmonary embolism. We investigated the effects of epidural anesthesia-induced sympathetic blockade, restricted to thoracic and lumba

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cde9ef3fdfabcd8701c98ab91fd3b6b4
https://doi.org/10.1097/00000539-200112000-00021

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Effects of an L-Selectin Antibody on the Pulmonary and Systemic Manifestations of Severe Smoke Inhalation Injuries in Sheep

Autor: Hal K. Hawkins, Lillian D. Traber, Daniel L. Traber, Frank C. Schmalstieg, Paul J. Schenarts, Hans G. Bone

Publikováno v: Journal of Burn Care & Rehabilitation. 21:229-240

Sheep were treated with either lymphocyte adhesion molecule (LAM)1-3, an antibody against L-selectin, (40 mg 1 hour before smoke inhalation and 35 mg 24 hours after smoke inhalation; n = 6) or equivalent volumes of 0.9% saline solution (n = 6). After

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7628b7e0dd77367e3451feace507bf20
https://doi.org/10.1097/00004630-200021030-00008

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Enhancement of axillary brachial plexus block anesthesia by coadministration of neostigmine1

Autor: Michael Booke, Hans G. Bone, Hugo Van Aken, Hartmut Bürkle

Publikováno v: Regional Anesthesia and Pain Medicine. 24:405-410

Background and Objectives The acetylcholinesterase inhibitor neostigmine has shown peripherally mediated analgesic action in recent preclinical and clinical studies. The present study investigates the effectiveness of adding neostigmine to a local an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e1b940088cfe34b49d29a943aa86498
https://doi.org/10.1016/s1098-7339(99)90005-6

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CONTINUOUS INFUSION OF PYRIDOXALATED HEMOGLOBIN POLYOXYETHYLENE CONJUGATE IN HYPERDYNAMIC SEPTIC SHEEP

Autor: Hans G. Bone, Daniel L. Traber, Roy McGuire, Stefanie R. Fischer, Lillian D. Traber, Paul J. Schenarts

Publikováno v: Shock. 10:69-76

Cell-free hemoglobin solutions can scavenge nitric oxide and therefore increase mean arterial pressure (MAP). The present study investigated the effects of a continuous low-dose infusion of modified hemoglobin during ovine hyperdynamic sepsis. 13 she

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2d38e072bc6a0c869468abe6a706ff1
https://doi.org/10.1097/00024382-199807000-00012

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Pyridoxalated hemoglobin polyoxyethylene conjugate reverses hyperdynamic circulation in septic sheep

Autor: Lillian D. Traber, Paul J. Schenarts, Stefanie R. Fischer, Hans G. Bone, Daniel L. Traber, Roy McGuire

Publikováno v: Journal of Applied Physiology. 84:1991-1999

We investigated the effects of modified hemoglobin on regional blood flow and function of different organs during hyperdynamic sepsis. Fourteen sheep were surgically prepared for the study. After a 5-day recovery period, a continuous infusion of live

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::464ae1e4c24874e0caa8f7063c02985c
https://doi.org/10.1152/jappl.1998.84.6.1991

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Nitric Oxide Synthase Inhibition Restores Hypoxic Pulmonary Vasoconstriction in Sepsis

Autor: Donald J. Deyo, Lillian D. Traber, Stefanie R. Fischer, Roy McGuire, Hans G. Bone, Daniel L. Traber

Publikováno v: American Journal of Respiratory and Critical Care Medicine. 156:833-839

Hypoxic pulmonary vasoconstriction (HPV) is inhibited by inhaled nitric oxide (NO) in healthy animals and is blunted in endotoxemia. We investigated whether the loss of HPV during sepsis could be reversed by NO synthase (NOS) inhibition. Hypoxic chal

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06a9bbfa1cda766d9d49d519676d9948
https://doi.org/10.1164/ajrccm.156.3.9701033

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