Zobrazeno 1 - 10
of 1 178
pro vyhledávání: '"Hans G, Drexler"'
Autor:
Alexandra G. Kouroukli, Anja Fischer, Helene Kretzmer, Emil Chteinberg, Nivethika Rajaram, Selina Glaser, Julia Kolarova, Pavel Bashtrykov, Stephan Mathas, Hans G. Drexler, Hitoshi Ohno, Ole Ammerpohl, Albert Jeltsch, Reiner Siebert, Susanne Bens
Publikováno v:
Blood Cancer Journal, Vol 13, Iss 1, Pp 1-4 (2023)
Externí odkaz:
https://doaj.org/article/a5d245bc7209422783c3ec33c962c0d4
Autor:
Theresa Bock, Moritz Bewarder, Onur Cetin, Natalie Fadle, Evi Regitz, Eva C. Schwarz, Jana Held, Sophie Roth, Stefan Lohse, Thorsten Pfuhl, Rabea Wagener, Sigrun Smola, Sören L. Becker, Rainer Maria Bohle, Lorenz Trümper, Reiner Siebert, Martin‐Leo Hansmann, Michael Pfreundschuh, Hans G. Drexler, Markus Hoth, Boris Kubuschok, Klaus Roemer, Klaus‐Dieter Preuss, Sylvia Hartmann, Lorenz Thurner
Publikováno v:
eJHaem, Vol 3, Iss 3, Pp 739-747 (2022)
Abstract Burkitt lymphoma (BL) represents the most aggressive B‐cell‐lymphoma. Beside the hallmark of IG‐MYC‐translocation, surface B‐cell receptor (BCR) is expressed, and mutations in the BCR pathway are frequent. Coincidental infections i
Externí odkaz:
https://doaj.org/article/dd8c74630d094db89e2da563ef835603
Autor:
Hilmar Quentmeier, Robert Geffers, Vivien Hauer, Stefan Nagel, Claudia Pommerenke, Cord C. Uphoff, Margarete Zaborski, Hans G. Drexler
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Overexpression of antiapoptotic BCL2 family proteins occurs in various hematologic malignancies and contributes to tumorigenesis by inhibiting the apoptotic machinery of the cells. Antagonizing BH3 mimetics provide an option for medication,
Externí odkaz:
https://doaj.org/article/88679ebb5bbd4ac6816fcd6fc2d8f448
Publikováno v:
Current Issues in Molecular Biology, Vol 43, Iss 3, Pp 2147-2156 (2021)
For many years, immortalized tumor cell lines have been used as reliable tools to understand the function of oncogenes and tumor suppressor genes. Today, we know that tumors can comprise subclones with common and with subclone-specific genetic altera
Externí odkaz:
https://doaj.org/article/32edc6e1ac44480295dfd3eb1c3c5edc
Publikováno v:
Current Oncology, Vol 28, Iss 3, Pp 1790-1794 (2021)
Chronic neutrophilic leukemia (CNL) is a rare myeloproliferative neoplasm that is genetically characterized by the absence of both the Philadelphia chromosome and BCR-ABL1 fusion gene and the high prevalence of mutations in the colony-stimulating fac
Externí odkaz:
https://doaj.org/article/8828deb130924eedbe201cca04f88164
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0246603 (2021)
Homeobox genes encode transcription factors which regulate basic processes in development and cell differentiation and are grouped into classes and subclasses according to sequence similarities. Here, we analyzed the activities of the 20 members stro
Externí odkaz:
https://doaj.org/article/0a399c097c4a46afb71ac25639ced821
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240120 (2020)
The NKL-code describes normal expression patterns of NKL homeobox genes in hematopoiesis. Aberrant expression of NKL homeobox gene subclass members have been reported in several hematopoietic malignancies including acute myeloid leukemia (AML). Here,
Externí odkaz:
https://doaj.org/article/1a12ff8a88d444959c8288688ac5ff68
Autor:
Chao Ding, Su-Ning Chen, Roderick A. F. Macleod, Hans G. Drexler, Stefan Nagel, De-Pei Wu, Ai-Ning Sun, Hai-Ping Dai
Publikováno v:
Upsala Journal of Medical Sciences, Vol 123, Iss 1, Pp 19-27 (2018)
Background: Emerging evidence has revealed that miRNAs can function as oncogenes or tumor suppressor genes in leukemia. The ectopic expression of miR-130a has been reported in chronic leukemia, but our understanding of the biological implications of
Externí odkaz:
https://doaj.org/article/d9a61acf99c746f9aab67c61241a5722
Autor:
Rebecca Auer
Publikováno v:
British Journal of Haematology. 117:1001-1001
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6edae26b45283c18f07d449bed567058
https://doi.org/10.1046/j.1365-2141.2002.35672.x
https://doi.org/10.1046/j.1365-2141.2002.35672.x
Autor:
Lamia Aït Ghezali, Atousa Arbabian, Hervé Roudot, Jean-Philippe Brouland, Fanny Baran-Marszak, Evelyn Salvaris, Andrew Boyd, Hans G. Drexler, Agnes Enyedi, Remi Letestu, Nadine Varin-Blank, Bela Papp
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 36, Iss 1, Pp 1-12 (2017)
Abstract Background Endoplasmic reticulum (ER) calcium storage and release play important roles in B lymphocyte maturation, survival, antigen-dependent cell activation and immunoglobulin synthesis. Calcium is accumulated in the endoplasmic reticulum
Externí odkaz:
https://doaj.org/article/54b8d92a60fa4f74a3e8c016bbff81d4