Supplementary Tables 1 through 5 from Variation in Mutation Spectrum Partly Explains Regional Differences in the Breast Cancer Risk of Female BRCA Mutation Carriers in the Netherlands

Autor: Geertruida H. de Bock, Jan C. Oosterwijk, Liesbeth Jansen, Annemarie H. van der Hout, Richard M. Brohet, Hans F. Vasen, Encarna B. Gómez-Garcia, Hanne E.J. Meijers-Heijboer, Theo A.M. van Os, Margreet G.E.M. Ausems, Arjen R. Mensenkamp, Christi J. van Asperen, Margriet Collée, Flora E. van Leeuwen, Matti A. Rookus, Marian J.E. Mourits, Dorina M. van der Kolk, Natalia Teixeira, Janet R. Vos

Supplementary Table 1. Clinical characteristics of BRCA1/2 carriers including index cases in the Northern Netherlands (study population) and in the rest of the Netherlands (reference population). Supplementary Table 2. Overview of number of carriers

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5038904ce7d8f9b24a5ec82049ab87b
https://doi.org/10.1158/1055-9965.22435510.v1

Whole Gene Capture Analysis of 15 CRC Susceptibility Genes in Suspected Lynch Syndrome Patients.

Autor: Anne M L Jansen, Marije A Geilenkirchen, Tom van Wezel, Shantie C Jagmohan-Changur, Dina Ruano, Heleen M van der Klift, Brendy E W M van den Akker, Jeroen F J Laros, Michiel van Galen, Anja Wagner, Tom G W Letteboer, Encarna B Gómez-García, Carli M J Tops, Hans F Vasen, Peter Devilee, Frederik J Hes, Hans Morreau, Juul T Wijnen

Publikováno v: PLoS ONE, Vol 11, Iss 6, p e0157381 (2016)

BACKGROUND AND AIMS:Lynch Syndrome (LS) is caused by pathogenic germline variants in one of the mismatch repair (MMR) genes. However, up to 60% of MMR-deficient colorectal cancer cases are categorized as suspected Lynch Syndrome (sLS) because no path

Externí odkaz: https://doaj.org/article/d3a653d49cec4ce4a0f3cab6d6023e4e

Surveillance for Hereditary Nonpolyposis Colorectal Cancer

Autor: Wouter H. de Vos tot Nederveen Cappel, Fokko M. Nagengast, Gerrit Griffioen, Fred H. Menko, Babs G. Taal, Jan H. Kleibeuker, Hans F. Vasen

Publikováno v: Diseases of the Colon & Rectum. 45:1588-1594

Hereditary nonpolyposis colorectal cancer is caused by germline mutations in DNA mismatch repair genes. Mutation carriers have a 60 to 85 percent risk of developing colorectal cancer. In the Netherlands hereditary nonpolyposis colorectal cancer famil

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3d8ed2ada19063fd0edddc5dd2408bff
https://doi.org/10.1007/s10350-004-7244-3

Breast Cancer Risk and 6q22.33: Combined Results from Breast Cancer Association Consortium and Consortium of Investigators on Modifiers of BRCA1/.

Autor: Kirchhoff, Tomas (AUTHOR), Gaudet, Mia M. (AUTHOR), Antoniou, Antonis C. (AUTHOR), McGuffog, Lesley (AUTHOR), Humphreys, Manjeet K. (AUTHOR), Dunning, Alison M. (AUTHOR), Bojesen, Stig E. (AUTHOR), Nordestgaard, Børge G. (AUTHOR), Flyger, Henrik (AUTHOR), Daehee Kang (AUTHOR), Keun-Young Yoo (AUTHOR), Dong-Young Noh (AUTHOR), Sei-Hyun Ahn (AUTHOR), Dork, Thilo (AUTHOR), Schürmann, Peter (AUTHOR), Karstens, Johann H. (AUTHOR), Hillemanns, Peter (AUTHOR), Couch, Fergus J. (AUTHOR), Olson, Janet (AUTHOR), Vachon, Celine (AUTHOR)

Publikováno v: PLoS ONE. Jun2012, Vol. 7 Issue 6, p1-10. 10p. 2 Diagrams, 4 Charts.

The clinical phenotype of hereditary versus sporadic prostate cancer: HPC definition revisited.

Autor: Cremers, Ruben G., Aben, Katja K., van Oort, Inge M., Sedelaar, J.P. Michiel, Vasen, Hans F., Vermeulen, Sita H., Kiemeney, Lambertus A.

Publikováno v: Prostate; Jul2016, Vol. 76 Issue 10, p897-904, 8p