Zobrazeno 1 - 10
of 393
pro vyhledávání: '"Hans Erik, Johnsen"'
Autor:
Alexander Schmitz, Rasmus Froberg Brøndum, Hans Erik Johnsen, Ulf-Henrik Mellqvist, Anders Waage, Peter Gimsing, Davine Hofste op Bruinink, Vincent van der Velden, Bronno van der Holt, Markus Hansson, Niels Frost Andersen, Ulf Christian Frølund, Carsten Helleberg, Fredrik H. Schjesvold, Lucia Ahlberg, Nina Gulbrandsen, Bjorn Andreasson, Birgitta Lauri, Einar Haukas, Julie Støve Bødker, Anne Stidsholt Roug, Martin Bøgsted, Marianne T. Severinsen, Henrik Gregersen, Niels Abildgaard, Pieter Sonneveld, Karen Dybkær
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-11 (2022)
Abstract Background Multiple myeloma remains an incurable disease with multiple relapses due to residual myeloma cells in the bone marrow of patients after therapy. Presence of small number of cancer cells in the body after cancer treatment, called m
Externí odkaz:
https://doaj.org/article/5436faba1b7640768aa73dd91ad91f57
Autor:
Davine Hofste op Bruinink, Stefania Oliva, Lucie Rihova, Alexander Schmitz, Milena Gilestro, Jeroen te Marvelde, Romana Kralova, Helle Høholt, Annemiek Broijl, Hans Erik Johnsen, Roman Hajek, Mario Boccadoro, Pieter Sonneveld, Paola Omedè, Vincent H.J. van der Velden
Publikováno v:
Haematologica, Vol 106, Iss 5 (2020)
Externí odkaz:
https://doaj.org/article/2e62a93c1e5a446097540e148434f786
Autor:
Anna A Schönherz, Julie Støve Bødker, Alexander Schmitz, Rasmus Froberg Brøndum, Lasse Hjort Jakobsen, Anne Stidsholt Roug, Marianne T Severinsen, Tarec C El-Galaly, Paw Jensen, Hans Erik Johnsen, Martin Bøgsted, Karen Dybkær
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0229593 (2020)
Acute myeloid leukaemia (AML) is characterised by phenotypic heterogeneity, which we hypothesise is a consequence of deregulated differentiation with transcriptional reminiscence of the normal compartment or cell-of-origin. Here, we propose a classif
Externí odkaz:
https://doaj.org/article/9d6f994c235e49a98003993006237fd0
Autor:
Thomas Yssing Michaelsen, Julia Richter, Rasmus Froberg Brøndum, Wolfram Klapper, Hans Erik Johnsen, Mads Albertsen, Karen Dybkær, Martin Bøgsted
Publikováno v:
Blood Advances, Vol 2, Iss 13, Pp 1542-1546 (2018)
Abstract: Gene expression profiling (GEP) by microarrays of diffuse large B-cell lymphoma (DLBCL) has enabled the categorization of DLBCL into activated B-cell–like and germinal center B-cell–like subclasses. However, as this does not fully embra
Externí odkaz:
https://doaj.org/article/224b5e4351244c1ca3044ca041080cfa
Autor:
Anders Ellern Bilgrau, Poul Svante Eriksen, Jakob Gulddahl Rasmussen, Hans Erik Johnsen, Karen Dybkaer, Martin Boegsted
Publikováno v:
Journal of Statistical Software, Vol 70, Iss 1, Pp 1-23 (2016)
Methods for clustering in unsupervised learning are an important part of the statistical toolbox in numerous scientific disciplines. Tewari, Giering, and Raghunathan (2011) proposed to use so-called Gaussian mixture copula models (GMCM) for general u
Externí odkaz:
https://doaj.org/article/84b4e21f196e488084f72668dfc2501d
Autor:
Mette Marcussen, Mads Sønderkær, Julie Støve Bødker, Maria Andersen, Søren Nielsen, Charles Vesteghem, Ilse Christiansen, Olav Jonas Bergmann, Martin Bøgsted, Karen Dybkær, Mogens Vyberg, Hans Erik Johnsen
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190709 (2018)
BACKGROUND:Radiation-therapy (RT) induces mucositis, a clinically challenging condition with limited prophylactic interventions and no predictive tests. In this pilot study, we applied global gene-expression analysis on serial human oral mucosa tissu
Externí odkaz:
https://doaj.org/article/a786d2c7443c4c56867a495a53ccd492
Autor:
Caroline Holm Nørgaard, Lasse Hjort Jakobsen, Andrew J Gentles, Karen Dybkær, Tarec Christoffer El-Galaly, Julie Støve Bødker, Alexander Schmitz, Preben Johansen, Tobias Herold, Karsten Spiekermann, Jennifer R Brown, Josephine L Klitgaard, Hans Erik Johnsen, Martin Bøgsted
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193249 (2018)
Diagnostic and prognostic evaluation of chronic lymphocytic leukemia (CLL) involves blood cell counts, immunophenotyping, IgVH mutation status, and cytogenetic analyses. We generated B-cell associated gene-signatures (BAGS) based on six naturally occ
Externí odkaz:
https://doaj.org/article/54d6f02da4e545279292e8d9f730b34d
Autor:
Mette Marcussen, Julie Støve Bødker, Heidi Søgaard Christensen, Preben Johansen, Søren Nielsen, Ilse Christiansen, Olav Jonas Bergmann, Martin Bøgsted, Karen Dybkær, Mogens Vyberg, Hans Erik Johnsen
Publikováno v:
PLoS ONE, Vol 12, Iss 1, p e0169286 (2017)
BACKGROUND:Toxicity of the oral and gastrointestinal mucosa induced by high-dose melphalan is a clinical challenge with no documented prophylactic interventions or predictive tests. The aim of this study was to describe molecular changes in human ora
Externí odkaz:
https://doaj.org/article/ccec468da4b74523a144344cd69fb349
Autor:
Hans Erik Johnsen, Martin Bøgsted, Alexander Schmitz, Julie Støve Bødker, Tarec Christoffer El-Galaly, Preben Johansen, Peter Valent, Niklas Zojer, Els Van Valckenborgh, Karin Vanderkerken, Mark van Duin, Pieter Sonneveld, Martin Perez-Andres, Alberto Orfao, Karen Dybkær
Publikováno v:
Haematologica, Vol 101, Iss 12 (2016)
The concept of the myeloma stem cell may have important therapeutic implications, yet its demonstration has been hampered by a lack of consistency in terms and definitions. Here, we summarize the current documentation and propose single-cell in vitro
Externí odkaz:
https://doaj.org/article/e79785be2eba47da8bab389a041151cf
Autor:
Steffen Falgreen, Anders Ellern Bilgrau, Rasmus Froberg Brøndum, Lasse Hjort Jakobsen, Jonas Have, Kasper Lindblad Nielsen, Tarec Christoffer El-Galaly, Julie Støve Bødker, Alexander Schmitz, Ken H Young, Hans Erik Johnsen, Karen Dybkær, Martin Bøgsted
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0163711 (2016)
BACKGROUND:Dozens of omics based cancer classification systems have been introduced with prognostic, diagnostic, and predictive capabilities. However, they often employ complex algorithms and are only applicable on whole cohorts of patients, making t
Externí odkaz:
https://doaj.org/article/8337afb6a5084bed981a2871a326875a