Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Hans Elmlund"'
Autor:
Henry Wietfeldt, Rubén Meana-Pañeda, Chiara Machello, Cyril F. Reboul, Cong T. S. Van, Sungin Kim, Junyoung Heo, Byung Hyo Kim, Sungsu Kang, Peter Ercius, Jungwon Park, Hans Elmlund
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract In situ structures of Platinum (Pt) nanoparticles (NPs) can be determined with graphene liquid cell transmission electron microscopy. Atomic-scale three-dimensional structural information about their physiochemical properties in solution is
Externí odkaz:
https://doaj.org/article/844cc00d7242450fa14efd9f0c129cac
Autor:
Yevgen Levdansky, Tobias Raisch, Justin C. Deme, Filip Pekovic, Hans Elmlund, Susan M. Lea, Eugene Valkov
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-8 (2023)
Abstract NOT1, NOT10, and NOT11 form a conserved module in the CCR4-NOT complex, critical for post-transcriptional regulation in eukaryotes, but how this module contributes to the functions of the CCR4-NOT remains poorly understood. Here, we present
Externí odkaz:
https://doaj.org/article/5824b314baae41ec8c157763276b6d09
Autor:
Junyoung Heo, Dongjun Kim, Hyesung Choi, Sungin Kim, Hoje Chun, Cyril F. Reboul, Cong T. S. Van, Dominika Elmlund, Soonmi Choi, Kihyun Kim, Younggil Park, Hans Elmlund, Byungchan Han, Jungwon Park
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Determining the 3D atomic structures of multi-element nanoparticles in their native liquid environment is crucial to understanding their physicochemical properties. Graphene liquid cell (GLC) TEM offers a platform to directly investigate nan
Externí odkaz:
https://doaj.org/article/5a0364ec22a04c7191db9801af27ad74
Autor:
Joseph Caesar, Cyril F. Reboul, Chiara Machello, Simon Kiesewetter, Molly L. Tang, Justin C. Deme, Steven Johnson, Dominika Elmlund, Susan M. Lea, Hans Elmlund
Publikováno v:
Journal of Structural Biology: X, Vol 4, Iss , Pp 100040- (2020)
We here introduce the third major release of the SIMPLE (Single-particle IMage Processing Linux Engine) open-source software package for analysis of cryogenic transmission electron microscopy (cryo-EM) movies of single-particles (Single-Particle Anal
Externí odkaz:
https://doaj.org/article/f09952d6ef1d4c0cb0bc4501bc6bc878
Autor:
Natalya V. Dudkina, Bradley A. Spicer, Cyril F. Reboul, Paul J. Conroy, Natalya Lukoyanova, Hans Elmlund, Ruby H. P. Law, Susan M. Ekkel, Stephanie C. Kondos, Robert J. A. Goode, Georg Ramm, James C. Whisstock, Helen R. Saibil, Michelle A. Dunstone
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-6 (2016)
The membrane attack complex is a heteromeric assembly of complement proteins where multiple copies of C9 are recruited by the C5b678 complex to form lytic pores in pathogen membranes. Here the authors present the structure of a soluble pore-like form
Externí odkaz:
https://doaj.org/article/a2649e95879f4957bec6ff1711385015
Autor:
Matthew J. Belousoff, Zohar Eyal, Mazdak Radjainia, Tofayel Ahmed, Rebecca S. Bamert, Donna Matzov, Anat Bashan, Ella Zimmerman, Satabdi Mishra, David Cameron, Hans Elmlund, Anton Y. Peleg, Shashi Bhushan, Trevor Lithgow, Ada Yonath
Publikováno v:
mBio, Vol 8, Iss 3 (2017)
ABSTRACT An unorthodox, surprising mechanism of resistance to the antibiotic linezolid was revealed by cryo-electron microscopy (cryo-EM) in the 70S ribosomes from a clinical isolate of Staphylococcus aureus. This high-resolution structural informati
Externí odkaz:
https://doaj.org/article/1ec9f31a43344b03be4992f9b65c601b
Autor:
Sarah N. Le, Christopher R. Brown, Stacy Harvey, Hinrich Boeger, Hans Elmlund, Dominika Elmlund
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3290 (2019)
The general transcription factor TFIID is a core promoter selectivity factor that recognizes DNA sequence elements and nucleates the assembly of a pre-initiation complex (PIC). The mechanism by which TFIID recognizes the promoter is poorly understood
Externí odkaz:
https://doaj.org/article/b3a1a53ec23a4fd8aee29674de1c2bdb
Autor:
Peter Ercius, Jungwon Park, Seulki Kang, Dohun Kang, Sangdeok Shim, Hans Elmlund, Cyril F. Reboul, S. K. Kang, Sungin Kim, Byung Hyo Kim, Chiara Machello, Taeghwan Hyeon, Junyoung Heo, So Jung Park, Jimin Kwag
Publikováno v:
Nano Letters. 21:1175-1183
Active sites and catalytic activity of heterogeneous catalysts is determined by their surface atomic structures. However, probing the surface structure at an atomic resolution is difficult, especially for solution ensembles of catalytic nanocrystals,
Autor:
Jacqueline A. Wilce, Bert L. Semler, Neelam Shah, Mehdi Y Matak, Matthew J Belousoff, Hans Elmlund, Hariprasad Venugopal, Naveen Vankadari, Joseph H. C. Nguyen, Matthew C.J. Wilce, Simone A. Beckham
Publikováno v:
Nucleic Acids Research
Nucleic acids research, vol 48, iss 14
Nucleic acids research, vol 48, iss 14
The poliovirus type I IRES is able to recruit ribosomal machinery only in the presence of host factor PCBP2 that binds to stem–loop IV of the IRES. When PCBP2 is cleaved in its linker region by viral proteinase 3CD, translation initiation ceases al
Autor:
Elsa A. Marquez, Christina Anne Mitchell, Christina M A Lucato, James C. Whisstock, Christopher J. Lupton, Cheng Huang, Michelle L. Halls, Ralf B. Schittenhelm, Srgjan Civciristov, Andrew M. Ellisdon, Chantel Mastos, Yong-Gang Chang, Hans Elmlund, Laura D’Andrea
Publikováno v:
Science signaling. 14(681)
The dual-specificity phosphatase PTEN functions as a tumor suppressor by hydrolyzing PI(3,4,5)P3 to PI(4,5)P2 to inhibit PI3K-AKT signaling and cellular proliferation. P-Rex2 is a guanine nucleotide exchange factor for Rho GTPases and can be activate