Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Hans E, Johnsen"'
Autor:
Andreas K. Øvlisen, Anders Oest, Mette D. Bendtsen, John Bæch, Preben Johansen, Line S. Lynggaard, Ingolf Mølle, Thomas B. Mortensen, Duruta Weber, Gideon Ertner, Claudia Schöllkopf, Jesper Q. Thomassen, Ove Juul Nielsen, Lene Sofie Granfeldt Østgård, Martin Bøgsted, Karen Dybkær, Hans E. Johnsen, Marianne T. Severinsen
Publikováno v:
Blood Advances, Vol 2, Iss 5, Pp 559-564 (2018)
Abstract: Stringent complete remission (sCR) of acute myeloid leukemia is defined as normal hematopoiesis after therapy. Less sCR, including non-sCR, was introduced as insufficient blood platelet, neutrophil, or erythrocyte recovery. These latter cha
Externí odkaz:
https://doaj.org/article/61ca51595feb468eb88a90fd0febbb7f
Autor:
Liesbeth Bieghs, Malene Brohus, Ida B Kristensen, Niels Abildgaard, Martin Bøgsted, Hans E Johnsen, Cheryl A Conover, Elke De Bruyne, Karin Vanderkerken, Michael T Overgaard, Mette Nyegaard
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0154256 (2016)
Insulin-like growth factor (IGF) signalling plays a key role in homing, progression, and treatment resistance in multiple myeloma (MM). In the extracellular environment, the majority of IGF molecules are bound to one of six IGF-binding proteins (IGFB
Externí odkaz:
https://doaj.org/article/1ec7239160444eb891a0a754cbf06314
Autor:
Martin Bøgsted, Anders E Bilgrau, Christopher P Wardell, Uta Bertsch, Alexander Schmitz, Julie S Bødker, Malene K Kjeldsen, Hartmut Goldschmidt, Gareth J Morgan, Karen Dybkaer, Hans E Johnsen
Publikováno v:
PLoS ONE, Vol 8, Iss 12, p e83252 (2013)
In a conceptual study of drug resistance we have used a preclinical model of malignant B-cell lines by combining drug induced growth inhibition and gene expression profiling. In the current report a melphalan resistance profile of 19 genes were weigh
Externí odkaz:
https://doaj.org/article/0778cf153500471da18c26b6bab43813
Autor:
Fiona M. Ross, Hervé Avet-Loiseau, Geneviève Ameye, Norma C. Gutiérrez, Peter Liebisch, Sheila O’Connor, Klara Dalva, Sonia Fabris, Adele M. Testi, Marie Jarosova, Clare Hodkinson, Anna Collin, Gitte Kerndrup, Petr Kuglik, Dariusz Ladon, Paolo Bernasconi, Brigitte Maes, Zuzana Zemanova, Kyra Michalova, Lucienne Michau, Kai Neben, N. Emil U. Hermansen, Katrina Rack, Alberto Rocci, Rebecca Protheroe, Laura Chiecchio, Hélène A Poirel, Pieter Sonneveld, Mette Nyegaard, Hans E. Johnsen
Publikováno v:
Haematologica, Vol 97, Iss 8 (2012)
The European Myeloma Network has organized two workshops on fluorescence in situ hybridization in multiple myeloma. The first aimed to identify specific indications and consensus technical approaches of current practice. A second workshop followed a
Externí odkaz:
https://doaj.org/article/2e46233e5d1b48ab884e4aedb089e04d
Autor:
Martin Boegsted, Johanne M Holst, Kirsten Fogd, Steffen Falgreen, Suzette Sørensen, Alexander Schmitz, Anne Bukh, Hans E Johnsen, Mette Nyegaard, Karen Dybkaer
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e19322 (2011)
BackgroundRecent reports indicate that in vitro drug screens combined with gene expression profiles (GEP) of cancer cell lines may generate informative signatures predicting the clinical outcome of chemotherapy. In multiple myeloma (MM) a range of ne
Externí odkaz:
https://doaj.org/article/3218c3b5ad1842f88ba61794b4c6099d
Autor:
Thomas Rasmussen, Jacob Haaber, Inger Marie Dahl, Lene M. Knudsen, Gitte B. Kerndrup, Marianne Lodahl, Hans E. Johnsen, Michael Kuehl
Publikováno v:
Haematologica, Vol 95, Iss 10 (2010)
Background Several laboratories have shown that cells with a memory B-cell phenotype can have the same clonotype as multiple myeloma tumor cells.Design and Methods The aim of this study was to determine whether some memory B cells have the same genet
Externí odkaz:
https://doaj.org/article/8a1a99ad89d14204aef6192ee641e20f
Autor:
Anouk Caraux, Bernard Klein, Bruno Paiva, Caroline Bret, Alexander Schmitz, Gwenny M. Fuhler, Nico A. Bos, Hans E Johnsen, Alberto Orfao, Martin Perez-Andres, for the Myeloma Stem Cell Network (MSCNET)
Publikováno v:
Haematologica, Vol 95, Iss 6 (2010)
Generation of B and plasma cells involves several organs with a necessary cell trafficking between them. A detailed phenotypic characterization of four circulating B-cell subsets (immature-, naïve-, memory- B-lymphocytes and plasma cells) of 106 hea
Externí odkaz:
https://doaj.org/article/7c41e9c966524084a4e4d6bc4c3a075b
Autor:
Hans E. Johnsen, Lene M. Knudsen, Anne K. Mylin, Peter Gimsing, Henrik Gregersen, Niels Abildgaard, Niels Frost Andersen, Torben Plesner, Annette Vangsted, Torben Mourits-Andersen
Publikováno v:
Hematology Reports, Vol 1, Iss 2, Pp e11-e11 (2009)
The impact of chemotherapy resistant B cells in multiple myeloma (MM) needs to be evaluated by in vivo targeted therapy. Here we report the conclusions from a phase II randomized, placebo controlled trial adding fludarabine to the induction with cycl
Externí odkaz:
https://doaj.org/article/907fa9c7ca9a4fb19ec79b759507505c
Autor:
Hans E. Johnsen, Bo Björkstrand, Tobias W. Klausen, Kari Remes, Astrid Gruber, Lene M. Knudsen, Olav J. Bergmann, Stig Lenhoff
Publikováno v:
Hematology Reports, Vol 1, Iss 1, Pp e2-e2 (2009)
Autologous stem cell transplantation is still considered the standard of care in young patients with multiple myeloma (MM). This disease is the most common indication for high-dose therapy (HDT) supported by hematopoietic stem-cell transplantation an
Externí odkaz:
https://doaj.org/article/3ba753057cae4299b0d208e667b731b2
Autor:
Aneire E. Khan, Valentina Gallo, Jakob Linseisen, Rudolf Kaaks, Sabine Rohrmann, Ole Raaschou-Nielsen, Anne Tjønneland, Hans E. Johnsen, Kim Overvad, Manuela M. Bergmann, Heiner Boeing, Vasiliki Benetou, Theodora Psaltopoulou, Antonia Trichopoulou, Giovanna Masala, Amalia Mattiello, Sara Grioni, Rosario Tumino, Roel C.H. Vermeulen, Petra H.M. Peeters, H. Bas Bueno-de-Mesquita, Martine M. Ros, Eiliv Lund, Eva Ardanaz, María-Dolores Chirlaque, Paula Jakszyn, Nerea Larrañaga, Adamina Losada, Nikolaus Becker, Alexandra Nieters, Carmen Martínez-García, Åsa Ågren, Göran Hallmans, Göran Berglund, Jonas Manjer, Naomi E. Allen, Timothy J. Key, Sheila Bingham, Kay Tee Khaw, Nadia Slimani, Pietro Ferrari, Paolo Boffetta, Teresa Norat, Paolo Vineis, Elio Riboli
Publikováno v:
Haematologica, Vol 93, Iss 6 (2008)
Background Non-Hodgkin’s lymphomas are a heterogeneous group of neoplasms arising from the lymphopoietic system including a wide range of subtypes of either B-cell or T-cell lymphomas. The few established risk factors for the development of these n
Externí odkaz:
https://doaj.org/article/a74dd5e296494f21b02d532e82c1e8ed