Zobrazeno 1 - 10
of 138
pro vyhledávání: '"Hans Dieter Flad"'
Autor:
Damir Muhvic, Volker El-Samalouti, Hans-Dieter Flad, Biserka Radoševic-Stašic, Daniel Rukavina
Publikováno v:
Mediators of Inflammation, Vol 10, Iss 3, Pp 155-162 (2001)
Background: Cell-wall components of Gram-positive and Gram-negative bacteria induce the production of cytokines in human peripheral blood mononuclear cells. These cytokines are the main mediators of local or systemic inflammatory reaction that can co
Externí odkaz:
https://doaj.org/article/3109a2aac00b41af974190d16f97886c
Publikováno v:
The Journal of Immunology. 169:2602-2610
In this study, we have examined the major platelet-derived CXC chemokines connective tissue-activating peptide III (CTAP-III), its truncation product neutrophil-activating peptide 2 (CXC chemokine ligand 7 (CXCL7)), as well as the structurally relate
Publikováno v:
Infection and Immunity. 70:4961-4967
Intracellular persistence of mycobacteria may result from an intricate balance between bacterial replication and signaling events leading to antimicrobial macrophage activities. Using human monocyte-derived macrophages, we investigated the relevance
Autor:
Hans-Dieter Flad, Evelin Grage-Griebenow, Martin Ernst, Helga Kahlert, Lore Brade, Rainer Zawatzky
Publikováno v:
European Journal of Immunology. 31:48-56
Human monocytes (Mo) consist of a major subset of Fcgamma-receptor I (CD64)-positive typical low accessory phagocytes, and a minor CD64(-) DC-like subset with high T cell-accessory and IFN-alpha-releasing activity. Both populations also differentiall
Autor:
Hans-Dieter Flad, Andreas Ludwig, Tobias Alexander Grimm, Buko Lindner, Ernst Brandt, Jan E. Ehlert
Publikováno v:
Blood. 96:2965-2972
The platelet-derived neutrophil-activating peptide 2 (NAP-2, 70 amino acids) belongs to the ELR+ CXC subfamily of chemokines. Similar to other members of this group, such as IL-8, NAP-2 activates chemotaxis and degranulation in neutrophils (polymorph
Publikováno v:
Toxicology. 152:37-45
Lipopolysaccharide (LPS), also known as endotoxin, is a compound of the cell wall of Gram-negative bacteria, which has been demonstrated to induce inflammatory reactions in vitro as well as in vivo, including lethal shock. A great number of different
Publikováno v:
Immunological Reviews. 177:204-216
Although platelet factor 4 (PF-4) and the beta-thromboglobulin (beta-TG) proteins represent the first chemokines to be discovered, their functional roles in host defense became clear only recently. Residing in platelets as storage proteins and becomi