Výsledky vyhledávání - "Hans D Lauenstein"

Airway hyper-responsiveness in lipopolysaccharide-challenged common marmosets (Callithrix jacchus)

Autor: Armin Braun, Tamara Becker, Christoph Curths, Horst Windt, Heinz-Gerd Hoymann, Judy Wichmann, Hans D Lauenstein, Franz-Josef Kaup, Jens M. Hohlfeld, Sascha Knauf, S Dunker

Publikováno v: Clinical Science (London, England : 1979)

Animal models with a high predictive value for human trials are needed to develop novel human-specific therapeutics for respiratory diseases. The aim of the present study was to examine lung-function parameters in marmoset monkeys (Callithrix jacchus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0cff2eeaee1e2d60fb7503006836c9a
https://publica.fraunhofer.de/handle/publica/235290

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Expression of VPAC1 in a murine model of allergic asthma

Autor: Tobias Welte, David Quarcoo, Armin Braun, David A. Groneberg, Hans D Lauenstein

Publikováno v: Journal of Occupational Medicine and Toxicology (London, England)

Vasoactive intestinal polypeptide (VIP) is a putative neurotransmitter of the inhibitory non-adrenergic non-cholinergic nervous system and influences the mammalian airway function in various ways. Hence known for bronchodilatory, immunomodulatory and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b09f299b1e8e4a2cc40189bea7085206
https://doi.org/10.1186/1745-6673-8-28

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A new model for testing human specific anti-inflammatory drugs: LPS-induced lung inflammation in the common marmoset

Autor: Armin Braun, Vanessa Neuhaus, Simone Switalla, Sophie Seehase, Martina Zoeller, Katherina Sewald, Hans D Lauenstein, Eberhard Fuchs, Christina Schlumbohm, Franz-Josef Kaup, Jens M. Hohlfeld, Sascha Knauf

The rising incidence and morbidity of chronic obstructive pulmonary diseases (COPD) is linked to the development of new human-specific anti-inflammatory and disease modifying therapeutics. New animal models that closely reflect anatomy and physiology

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b2ebcc40e4c28eefb82b98b4053ff42
https://publica.fraunhofer.de/handle/publica/230462

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Surfactant protein D modulates allergen particle uptake and inflammatory response in a human epithelial airway model

Autor: Peter Gehr, Armin Braun, Carsten Schleh, Fabian Blank, Veit J. Erpenbeck, Norbert Krug, Matthias Nassimi, Barbara Rothen-Rutishauser, Jens M. Hohlfeld, Hans D Lauenstein

Publikováno v: Schleh, Carsten; Rothen-Rutishauser, Barbara M.; Blank, Fabian; Lauenstein, Hans D.; Nassimi, Matthias; Krug, Norbert; Braun, Armin; Erpenbeck, Veit J.; Gehr, Peter; Hohlfeld, Jens M. (2012). Surfactant protein D modulates allergen particle uptake and inflammatory response in a human epithelial airway model. Respiratory research, 13(8), p. 8. London: BioMed Central 10.1186/1465-9921-13-8
Respiratory Research
Respiratory Research, Vol 13, Iss 1, p 8 (2012)

Background Allergen-containing subpollen particles (SPP) are released from whole plant pollen upon contact with water or even high humidity. Because of their size SPP can preferentially reach the lower airways where they come into contact with surfac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e84f3f9cc7edbe2ad2055dc6d15cebc
https://boris.unibe.ch/15067/1/1465-9921-13-8.pdf

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Bronchoconstriction in nonhuman primates: a species comparison

Autor: Armin Braun, Stefan Uhlig, Marco Schlepütz, Anna Rebekka Kuehl, M. Zöller, Christian Martin, Franz Josef Kaup, Sophie Seehase, Hans D Lauenstein, Eberhard Fuchs, Carla Winkler, Christina Schlumbohm, Kerstin Mätz-Rensing, Katherina Sewald, Simone Switalla

Publikováno v: Journal of applied physiology (Bethesda, Md. : 1985). 111(3)

Bronchoconstriction is a characteristic symptom of various chronic obstructive respiratory diseases such as chronic obstructive pulmonary disease and asthma. Precision-cut lung slices (PCLS) are a suitable ex vivo model to study physiological mechani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b806b4e743f377f82b26555cf0bd39
https://pubmed.ncbi.nlm.nih.gov/21700889

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Allergen particle binding by human primary bronchial epithelial cells is modulated by surfactant protein D

Autor: Matthias Nassimi, Armin Braun, Jens M. Hohlfeld, Hans D Lauenstein, Carla Winkler, Norbert Krug, Veit J. Erpenbeck, Carsten Schleh

Publikováno v: Respir. Res. 11:83 (2010)
Respiratory Research
Respiratory Research, Vol 11, Iss 1, p 83 (2010)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::771eb387564fdd03893a4283b955dfaa
https://push-zb.helmholtz-muenchen.de/frontdoor.php?source_opus=457

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The effect of titanium dioxide nanoparticles on pulmonary surfactant function and ultrastructure

Autor: Hans D Lauenstein, Norbert Krug, Carsten Schleh, Karin Pulskamp, Christian Mühlfeld, Armin Braun, Veit J. Erpenbeck, Jens M. Hohlfeld, Matthias Nassimi, Andreas Schmiedl

Publikováno v: Respiratory Research
Respiratory Research, Vol 10, Iss 1, p 90 (2009)

Background Pulmonary surfactant reduces surface tension and is present at the air-liquid interface in the alveoli where inhaled nanoparticles preferentially deposit. We investigated the effect of titanium dioxide (TiO2) nanosized particles (NSP) and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f298d672ce7ba8b657726ebeda2407c
https://doi.org/10.1186/1465-9921-10-90

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