Molecular Epidemiology of Underreported Emerging Zoonotic Pathogen Streptococcus suis in Europe

Autor: Jaime Brizuela, Thomas J. Roodsant, Qureisha Hasnoe, Boas C.L. van der Putten, Jana Kozakova, Hans-Christian Slotved, Mark van der Linden, Ilse G.A. de Beer-Schuurman, Ewa Sadowy, Juan Antonio Sáez-Nieto, Victoria J. Chalker, Kees C.H. van der Ark, Constance Schultsz

Publikováno v: Emerging Infectious Diseases, Vol 30, Iss 3, Pp 413-422 (2024)

Streptococcus suis, a zoonotic bacterial pathogen circulated through swine, can cause severe infections in humans. Because human S. suis infections are not notifiable in most countries, incidence is underestimated. We aimed to increase insight into t

Externí odkaz: https://doaj.org/article/59fad5f5a60d4cee9af88d525d35af0f

Identification of antibiotic induced persister cells in Streptococcus agalactiae.

Autor: Nanna Boll Greve, Hans-Christian Slotved, John Elmerdahl Olsen, Line Elnif Thomsen

Publikováno v: PLoS ONE, Vol 19, Iss 6, p e0303271 (2024)

Antibiotic persistence is a phenomenon, where a small fraction of a bacterial population expresses a phenotypic variation that allows them to survive antibiotic treatment, which is lethal to the rest of the population. These cells are called persiste

Externí odkaz: https://doaj.org/article/ca1d31060b1d49d8855872c8b2f433ae

Trends in invasive bacterial diseases during the first 2 years of the COVID-19 pandemic: analyses of prospective surveillance data from 30 countries and territories in the IRIS Consortium

Autor: David Shaw, MBBCh, Raquel Abad, PhD, Zahin Amin-Chowdhury, MSc, Adriana Bautista, MSc, Desiree Bennett, PhD, Karen Broughton, MSc, Bin Cao, ProfMD, Carlo Casanova, PhD, Eun Hwa Choi, ProfMD, Yiu-Wai Chu, PhD, Heike Claus, PhD, Juliana Coelho, PhD, Mary Corcoran, PhD, Simon Cottrell, PhD, Robert Cunney, MB, Lize Cuypers, PhD, Tine Dalby, PhD, Heather Davies, NZCS, Linda de Gouveia, NatDipMedTech, Ala-Eddine Deghmane, PhD, Walter Demczuk, BSc, Stefanie Desmet, PhD, Mirian Domenech, PhD, Richard Drew, MD, Mignon du Plessis, PhD, Carolina Duarte, PhD, Helga Erlendsdóttir, ProfMSc, Norman K Fry, PhD, Kurt Fuursted, MD, Thomas Hale, ProfPhD, Desiree Henares, PhD, Birgitta Henriques-Normark, ProfMD, Markus Hilty, PhD, Steen Hoffmann, MD, Hilary Humphreys, ProfMD, Margaret Ip, ProfMSc, Susanne Jacobsson, PhD, Christopher Johnson, PhD, Jillian Johnston, MBBS, Keith A Jolley, PhD, Aníbal Kawabata, Jana Kozakova, MD, Karl G Kristinsson, ProfMD, Pavla Krizova, MD, Alicja Kuch, PhD, Shamez Ladhani, MD, Thiên-Trí Lâm, MD, María Eugenia León, MSc, Laura Lindholm, MSc, David Litt, PhD, Martin C J Maiden, ProfPhD, Irene Martin, BSc, Delphine Martiny, ProfPhD, Wesley Mattheus, PhD, Noel D McCarthy, ProfDPhil, Mary Meehan, PhD, Susan Meiring, MBChB, Paula Mölling, PhD, Eva Morfeldt, PhD, Julie Morgan, HND, Robert Mulhall, PhD, Carmen Muñoz-Almagro, ProfMD, David Murdoch, ProfMD, Joy Murphy, BA Hons, Martin Musilek, PhD, Alexandre Mzabi, MD, Ludmila Novakova, MSc, Shahin Oftadeh, PhD, Amaresh Perez-Argüello, MLT, Maria Pérez-Vázquez, PhD, Monique Perrin, MD, Malorie Perry, MSc, Benoit Prevost, PhD, Maria Roberts, BSc(Hons), Assaf Rokney, PhD, Merav Ron, PhD, Olga Marina Sanabria, MPH, Kevin J Scott, PhD, Carmen Sheppard, PhD, Lotta Siira, PhD, Vitali Sintchenko, ProfPhD, Anna Skoczyńska, ProfPhD, Monica Sloan, Hans-Christian Slotved, DMSc, Andrew J Smith, ProfFRCPath, Anneke Steens, PhD, Muhamed-Kheir Taha, ProfMD, Maija Toropainen, PhD, Georgina Tzanakaki, ProfPhD, Anni Vainio, PhD, Mark P G van der Linden, PhD, Nina M van Sorge, ProfPhD, Emmanuelle Varon, MD, Sandra Vohrnova, MD, Anne von Gottberg, ProfPhD, Jose Yuste, PhD, Rosemeire Zanella, PhD, Fei Zhou, PhD, Angela B Brueggemann, ProfDPhil

Publikováno v: The Lancet: Digital Health, Vol 5, Iss 9, Pp e582-e593 (2023)

Summary: Background: The Invasive Respiratory Infection Surveillance (IRIS) Consortium was established to assess the impact of the COVID-19 pandemic on invasive diseases caused by Streptococcus pneumoniae, Haemophilus influenzae, Neisseria meningitid

Externí odkaz: https://doaj.org/article/384c876404e140c8b5a86eec7ad5243e

Predicting β-lactam susceptibility from the genome of Streptococcus pneumoniae and other mitis group streptococci

Autor: Helle Brander Eriksen, Kurt Fuursted, Anders Jensen, Christian Salgård Jensen, Xiaohui Nielsen, Jens Jørgen Christensen, Patricia Shewmaker, Ana Rita Rebelo, Frank Møller Aarestrup, Kristian Schønning, Hans-Christian Slotved, the One Day in Denmark (ODiD) Consortium

Publikováno v: Frontiers in Microbiology, Vol 14 (2023)

IntroductionFor Streptococcus pneumoniae, β-lactam susceptibility can be predicted from the amino acid sequence of the penicillin-binding proteins PBP1a, PBP2b, and PBP2x. The combination of PBP-subtypes provides a PBP-profile, which correlates to a

Externí odkaz: https://doaj.org/article/a8489f2c792242188a9c2b7d3f7d1225

Evaluation of molecular typing for national surveillance of invasive clinical Haemophilus influenzae isolates from Denmark

Autor: Hans-Christian Slotved, Thor Bech Johannesen, Marc Stegger, Kurt Fuursted

Publikováno v: Frontiers in Microbiology, Vol 13 (2022)

Haemophilus influenzae is a gram-negative coccobacillus known to cause respiratory and invasive infections. It can possess a polysaccharide capsule that can be categorized into six different serotypes (i.e., Hia, Hib, Hic, Hid, Hie, and Hif) and non-

Externí odkaz: https://doaj.org/article/ebdb2d9c3e13453eb57c760de4b398d6