Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Hans Christian Kornau"'
Autor:
Jakob Kreye, S. Momsen Reincke, Stefan Edelburg, Lara M. Jeworowski, Hans-Christian Kornau, Jakob Trimpert, Peter Hombach, Sophia Halbe, Volker Nölle, Martin Meyer, Stefanie Kattenbach, Elisa Sánchez-Sendin, Marie L. Schmidt, Tatjana Schwarz, Ruben Rose, Andi Krumbholz, Sophie Merz, Julia M. Adler, Kathrin Eschke, Azza Abdelgawad, Dietmar Schmitz, Leif E. Sander, Uwe Janssen, Victor M. Corman, Harald Prüss
Publikováno v:
iScience, Vol 26, Iss 4, Pp 106323- (2023)
Summary: The recurrent emerging of novel viral variants of concern (VOCs) with evasion of preexisting antibody immunity upholds severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) case numbers and maintains a persistent demand for updated th
Externí odkaz:
https://doaj.org/article/f239808c0b29429ea48ba7fde057f1ba
Autor:
Lucie Y. Li, Jakob Kreye, Malgorzata Burek, César Cordero-Gomez, Paula C. Barthel, Elisa Sánchez-Sendín, Hans-Christian Kornau, Dietmar Schmitz, Madeleine Scharf, Patrick Meybohm, S. Momsen Reincke, Harald Prüss, Markus Höltje
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Introduction: The antibody repertoire from CSF-derived antibody-secreting cells and memory B-cells in patients with encephalitis contains a considerable number of antibodies that do not target the disease-defining autoantigen such as the GABA or NMDA
Externí odkaz:
https://doaj.org/article/b16392a720e4433bb60da4f1eeaa4644
Autor:
Yuko Fukata, Rosanna P. Sammons, Daniel Parthier, Masaki Fukata, Alexander B. Kowski, Dietmar Schmitz, Hans-Christian Kornau, Barbara Imbrosci, Jakob Kreye, Harald Prüss, Sarah Kurpjuweit, Alexander Stumpf
Publikováno v:
Annals of neurology 87(3), 405-418 (2020). doi:10.1002/ana.25666
Objective Leucine-rich glioma-inactivated 1 (LGI1) encephalitis is the second most common antibody-mediated encephalopathy, but insight into the intrathecal B-cell autoimmune response, including clonal relationships, isotype distribution, frequency,
Autor:
Tatjana Schwarz, Christian Drosten, Andreas Wieser, Lara Maria Jeworowski, Barner M, Meng Yuan, Yuanzi Hua, Harald Prüss, Jakob Kreye, Homeyer Ma, Tabea M. Eser, Marie Luisa Schmidt, Stöffler L, Gänzer H, Ramberger M, Dietmar Schmitz, Victor M. Corman, van Hoof S, Elisa Sanchez-Sendin, Hans-Christian Kornau, Horler J, Michael Hoelscher, Ian A. Wilson, Foverskov Rasmussen H, Désirée Kunkel, Wardenburg Nv, Guenter Weiss, Inge Kroidl, S. M. Reincke, Wenli Yu, Brandl Se, Christof Geldmacher, Henry Tien, Huo S
SARS-CoV-2 Beta variant of concern (VOC) resists neutralization by major classes of antibodies from non-VOC COVID-19 patients and vaccinated individuals. Here, serum of Beta variant infected patients revealed reduced cross-neutralization of non-VOC v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd6387a4f7e618b564d520c58dcff189
https://doi.org/10.1101/2021.09.30.462420
https://doi.org/10.1101/2021.09.30.462420
Autor:
Jakob, Kreye, Sukhvir K, Wright, Adriana, van Casteren, Laura, Stöffler, Marie-Luise, Machule, S Momsen, Reincke, Marc, Nikolaus, Scott, van Hoof, Elisa, Sanchez-Sendin, Marie A, Homeyer, César, Cordero Gómez, Hans-Christian, Kornau, Dietmar, Schmitz, Angela M, Kaindl, Philipp, Boehm-Sturm, Susanne, Mueller, Max A, Wilson, Manoj A, Upadhya, Divya R, Dhangar, Stuart, Greenhill, Gavin, Woodhall, Paul, Turko, Imre, Vida, Craig C, Garner, Jonathan, Wickel, Christian, Geis, Yuko, Fukata, Masaki, Fukata, Harald, Prüss
Publikováno v:
Journal of experimental medicine 218(11), e20210012 (2021). doi:10.1084/jem.20210012
Autoantibodies targeting the GABAA receptor (GABAAR) hallmark an autoimmune encephalitis presenting with frequent seizures and psychomotor abnormalities. Their pathogenic role is still not well-defined, given the common overlap with further autoantib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::558c211c0c6012a230acc34d3a3c85ef
https://publications.aston.ac.uk/id/eprint/43131/1/2021.01.28.428602v1.full.pdf
https://publications.aston.ac.uk/id/eprint/43131/1/2021.01.28.428602v1.full.pdf
Autor:
Jawad Ahmed, Sayyed Fahim Shah, Emilie Falconnet, Hyunglok Chung, Emmanuelle Ranza, Stylianos E. Antonarakis, Tayseer Abdel Magid, Azhar Ali Qaisar, Ralf Scholz, Muhammad Ansar, Muhammad T. Sarwar, Hesham Aldhalaan, Paul C. Marcogliese, Federico Santoni, Ali Al-Otaibi, Eissa Faqeih, Mohammad Nael Elagabani, Hugo J. Bellen, Erik-Jan Kamsteeg, Sohail A. Paracha, Thomas A. Ravenscroft, Hans-Christian Kornau, Periklis Makrythanasis, Ali Alasmari
Publikováno v:
American Journal of Human Genetics, 105, 907-920
Am J Hum Genet
American Journal of Human Genetics, 105, 5, pp. 907-920
Am J Hum Genet
American Journal of Human Genetics, 105, 5, pp. 907-920
We report two consanguineous families with probands that exhibit intellectual disability, developmental delay, short stature, aphasia, and hypotonia in which homozygous non-synonymous variants were identified in IQSEC1 (GenBank: NM_001134382.3). In a
Autor:
Craig C. Garner, Angela M. Kaindl, Sukhvir Wright, Paul Turko, Imre Vida, Jonathan Wickel, A. van Casteren, H. Pruess, L. Stoeffler, M. Nikolaus, M.-L. Machule, Max A Wilson, Christian Geis, S. van Hoof, Stuart D. Greenhill, Masaki Fukata, Jakob Kreye, Yuko Fukata, Elisa Sanchez-Sendin, Hans-Christian Kornau, S. M. Reincke, Gavin L. Woodhall
Autoantibodies targeting the GABAA receptor (GABAAR) hallmark an autoimmune encephalitis presenting with frequent seizures and psychomotor abnormalities. Their pathogenic role is still not well-defined, given the common overlap with further autoantib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c623f9c08956048ce2e9777d1dc0fe1
https://doi.org/10.1101/2021.01.28.428602
https://doi.org/10.1101/2021.01.28.428602
Autor:
Atsushi Nambu, Makoto Sanbo, Xiumin Chen, Yuko Fukata, Harald Prüss, Hans-Christian Kornau, Hiroki Inahashi, Masumi Hirabayashi, Teppei Goto, Roger A. Nicoll, Yoko Hirano, Atsushi Yamagata, Satomi Chiken, Masaki Fukata, Shuya Fukai, Hiromi Sano
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America 118(3), e2022580118-(2021). doi:10.1073/pnas.2022580118
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America
Significance This study addresses a fundamental question in neuroscience, namely how does the presynaptic component of the synapse precisely align with the postsynaptic component? This is essential for the proper transmission of signals across the sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68628950b12bc111c5ad4ecbb0ec6b28
Autor:
Georg Köhr, Dušica Briševac, Dan Du, Ralf Scholz, Mohammad Nael Elagabani, Hans-Christian Kornau
Publikováno v:
Journal of neurochemistry 157(3), 666-683 (2021). doi:10.1111/jnc.15230
Journal of Neurochemistry : official journal of the International Society for Neurochemistry
Journal of Neurochemistry : official journal of the International Society for Neurochemistry
Fragile X syndrome (FXS), the most common inherited cause of intellectual disability, results from silencing of the fragile X mental retardation gene 1 (FMR1). The analyses of FXS patients’ brain autopsies revealed an increased density of immature
Autor:
Julius Hoffmann, Laura Stöffler, Christian Drosten, Ian A. Wilson, Stefan Hippenstiel, Niels von Wardenburg, Jakob Trimpert, Xueyong Zhu, Dietmar Schmitz, Scott van Hoof, Andreas C. Hocke, Florian Kurth, Marcel A. Müller, Lucie Y Li, Hejun Liu, Leif E. Sander, Christiana Franke, Daria Vladimirova, Chang-Chun D Lee, Anja Richter, Marie Luisa Schmidt, Kristina Dietert, Elisa Sanchez-Sendin, Jakob Kreye, Karl Skriner, Harald Prüss, Lara Maria Jeworowski, Martin Witzenrath, Marie A Homeyer, Nikolaus Osterrieder, Nicholas C. Wu, Daniel Wendisch, Victor M. Corman, Paula Charlotte Barthel, Matthias Endres, Luca D. Bertzbach, Azza Abdelgawad, Meng Yuan, Norbert Suttorp, S. Momsen Reincke, Markus Höltje, Tatjana Schwarz, Hans Christian Kornau, Achim D. Gruber
Publikováno v:
Cell
Cell 183(4), 1058-1069.e19 (2020). doi:10.1016/j.cell.2020.09.049
Cell 183(4), 1058-1069.e19 (2020). doi:10.1016/j.cell.2020.09.049
The emergence of SARS-CoV-2 led to pandemic spread of coronavirus disease 2019 (COVID-19), manifesting with respiratory symptoms and multi-organ dysfunction. Detailed characterization of virus-neutralizing antibodies and target epitopes is needed to