Small Intestinal Permeability and Metabolomic Profiles in Feces and Plasma Associate With Clinical Response in Patients With Active Psoriatic Arthritis Participating in a Fecal Microbiota Transplantation Trial: Exploratory Findings From the FLORA Trial

Autor: Maja Skov Kragsnaes, Jesus Miguens Blanco, Benjamin H. Mullish, Jose Ivan Serrano‐Contreras, Jens Kjeldsen, Hans Christian Horn, Jens Kristian Pedersen, Heidi Lausten Munk, Anna Christine Nilsson, Ash Salam, Matthew R. Lewis, Elena Chekmeneva, Karsten Kristiansen, Julian R. Marchesi, Torkell Ellingsen

Publikováno v: ACR Open Rheumatology, Vol 5, Iss 11, Pp 583-593 (2023)

Objective We investigated intestinal permeability and fecal, plasma, and urine metabolomic profiles in methotrexate‐treated active psoriatic arthritis (PsA) and how this related to clinical response following one sham or fecal microbiota transplant

Externí odkaz: https://doaj.org/article/0854ce52aa8648ecb3c6b125d73d5e5c

The impact of sex and disease classification on patient-reported outcome measures in axial spondyloarthritis: a descriptive prospective cross-sectional study

Autor: Rikke A. Andreasen, Lars E. Kristensen, Kenneth Egstrup, Xenofon Baraliakos, Vibeke Strand, Hans Christian Horn, Inger M. J. Hansen, Robin Christensen, Torkell Ellingsen

Publikováno v: Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-11 (2019)

Abstract Background The aim of this study was to explore the impact of sex and disease classification on outcomes in axial spondyloarthritis (axSpA) patients, including both radiographic (r-) axSpA and non-radiographic (nr-) axSpA, in males and femal

Externí odkaz: https://doaj.org/article/b0b1eed2f57c4bb3885cf2585210e7e4

The Prognostic Value of Pain Phenotyping in Relation to Treatment Outcomes in Patients with Axial Spondyloarthritis Treated in Clinical Practice: A Prospective Cohort Study

Autor: Robin Christensen, Inger Marie Jensen Hansen, Claus Aalykke, Lars Erik Kristensen, Berit Schiøttz-Christensen, Vibeke Strand, Xenofon Baraliakos, Rikke Asmussen Andreasen, Hans Christian Horn, Jimmi Wied, Torkell Ellingsen, Kenneth Egstrup

Publikováno v: Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 10, Iss 1469, p 1469 (2021)
Andreasen, R A, Kristensen, L E, Egstrup, K, Baraliakos, X, Strand, V, Horn, H C, Wied, J, Schiottz-Christensen, B, Aalykke, C, Hansen, I M J, Ellingsen, T & Christensen, R 2021, ' The Prognostic Value of Pain Phenotyping in Relation to Treatment Outcomes in Patients with Axial Spondyloarthritis Treated in Clinical Practice : A Prospective Cohort Study ', Journal of Clinical Medicine, vol. 10, no. 7, 1469 . https://doi.org/10.3390/jcm10071469
Volume 10
Issue 7
Andreasen, R A, Kristensen, L E, Egstrup, K, Baraliakos, X, Strand, V, Horn, H C, Wied, J, Schiøttz-Christensen, B, Aalykke, C, Hansen, I M J, Ellingsen, T & Christensen, R 2021, ' The prognostic value of pain phenotyping in relation to treatment outcomes in patients with axial spondyloarthritis treated in clinical practice : a prospective cohort study ', Journal of Clinical Medicine, vol. 10, no. 7, 1469 . https://doi.org/10.3390/jcm10071469

Despite the control of inflammation, many patients with axial spondyloarthritis (axSpA) still report pain as a significant concern. Our objective was to explore the prognostic value of the painDETECT questionnaire (PDQ) in relation to treatment outco

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::682458abdc7fa50f1b7e676d702ec5f8
http://europepmc.org/articles/PMC8038186

Safety and efficacy of faecal microbiota transplantation for active peripheral psoriatic arthritis: an exploratory randomised placebo-controlled trial

Autor: Finn Moeller Pedersen, Jens Kristian Pedersen, Maja Skov Kragsnaes, Torkell Ellingsen, Vibeke Andersen, Karsten Kristiansen, Hans Christian Horn, Robin Christensen, Dorte Kinggaard Holm, Hanne Marie Holt, Sören Möller, Palle Ahlquist, Jens Kjeldsen, Søren Andreas Just, Maarten de Wit, Heidi Lausten Munk

Publikováno v: Kragsnaes, M S, Kjeldsen, J, Horn, H C, Munk, H L, Pedersen, J K, Just, S A, Ahlquist, P, Pedersen, F M, de Wit, M, Möller, S, Andersen, V, Kristiansen, K, Kinggaard Holm, D, Holt, H M, Christensen, R & Ellingsen, T 2021, ' Safety and efficacy of faecal microbiota transplantation for active peripheral psoriatic arthritis : an exploratory randomised placebo-controlled trial ', Annals of the rheumatic diseases, vol. 80, no. 9, pp. 1158-1167 . https://doi.org/10.1136/annrheumdis-2020-219511

ObjectivesAlthough causality remains to be established, targeting dysbiosis of the intestinal microbiota by faecal microbiota transplantation (FMT) has been proposed as a novel treatment for inflammatory diseases. In this exploratory, proof-of-concep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea962d502609d61362e55fe8568ef2b4
https://pubmed.ncbi.nlm.nih.gov/33926922

Pamidronate in chronic non-bacterial osteomyelitis:a randomized, double-blinded, placebo-controlled pilot trial

Autor: Caroline Marie Andreasen, Anne Grethe Jurik, Hans Christian Horn, Ellen Margrethe Hauge, Troels Bille Folkmar, Bent Deleuran, T Herlin

Publikováno v: Andreasen, C M, Jurik, A G, Deleuran, B W, Horn, H C, Folkmar, T B, Herlin, T & Hauge, E M 2020, ' Pamidronate in chronic non-bacterial osteomyelitis : a randomized, double-blinded, placebo-controlled pilot trial ', Scandinavian Journal of Rheumatology, vol. 49, no. 4, pp. 312-322 . https://doi.org/10.1080/03009742.2020.1724324

Objective: This is the first randomized double-blinded, placebo-controlled pilot trial to investigate the efficacy of pamidronate in reducing radiological and clinical disease activity in chronic non-bacterial osteomyelitis (CNO). Method: Patients re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b42fbaf2e2798faf785f1a88964e7f3c
https://portal.findresearcher.sdu.dk/da/publications/88cdab09-6273-4398-bb26-806c32f7e994