Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Hans C. van Mierlo"'
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The association between schizophrenia and the immune system: Review of the evidence from unbiased ‘omic-studies’
Autor: Aron Schot, Hans C. van Mierlo, Lot D. de Witte, Marco P. Boks
Publikováno v: Schizophrenia Research. 217:114-123
A role for immune processes in the pathogenesis of schizophrenia has been suggested by genetic and epidemiological studies, as well as cross-sectional studies on blood and brain samples. However, results are heterogeneous, which is likely caused by l
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11bb3cd7dfc8512e524ad41a92ae87ad
https://doi.org/10.1016/j.schres.2019.05.028
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3
Distinct non-inflammatory signature of microglia in post-mortem brain tissue of patients with major depressive disorder
Autor: Gijsje J. L. J. Snijders, Josef Priller, Lot de Witte, Towfique Raj, Evan Udine, Chotima Bӧttcher, Amber Berdenis van Berlekom, Elly M. Hol, Marjolein A. M. Sneeboer, Marco P. Boks, Alba Fernández-Andreu, René S. Kahn, Hans C. van Mierlo, Paul R. Ormel
Publikováno v: Molecular Psychiatry, 26, 3336-3349
Molecular Psychiatry, 26, 7, pp. 3336-3349
Molecular Psychiatry, 26, 3336-3349. Nature Publishing Group
Molecular psychiatry 26, 3336-3349 (2021). doi:10.1038/s41380-020-00896-z
Contains fulltext : 244590.pdf (Publisher’s version ) (Closed access) Findings from epidemiological studies, biomarker measurements and animal experiments suggest a role for aberrant immune processes in the pathogenesis of major depressive disorder
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1a70fa74b6b11eab87c1c0212b760b1
http://hdl.handle.net/2066/244590
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4
The association between antibodies to neurotropic pathogens and bipolar disorder : A study in the Dutch Bipolar (DB) Cohort and meta-analysis
Autor: Marieke J. H. Begemann, Hans C. van Mierlo, Manja Litjens, René S. Kahn, Lot de Witte, Marco P. Boks, Arjen L. Sutterland, Roel A. Ophoff, G. Snijders
Publikováno v: Translational psychiatry, vol 9, iss 1
Translational psychiatry, 9(1):311. Nature Publishing Group
Translational Psychiatry, 9(1). Nature Publishing Group
Exposure to neurotropic pathogens has been hypothesized to be a risk factor for the development of bipolar disorder (BD). However, evidence so far is inconsistent. We, therefore, analyzed the seroprevalence and titer levels of IgG antibodies against
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad568bfb38abbbf708ef6e2f4da03c2f
https://hdl.handle.net/1874/391724
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5
Microglia in post-mortem brain tissue of patients with bipolar disorder are not immune activated
Autor: Manja Litjens, G. Snijders, Lot D. de Witte, Elly M. Hol, Alba Fernández-Andreu, Woutje M. Berdowski, Marjolein A. M. Sneeboer, Hans C. van Mierlo, Amber Berdenis van Berlekom, René S. Kahn
Publikováno v: Translational Psychiatry, 9(1). Nature Publishing Group
Translational Psychiatry, Vol 9, Iss 1, Pp 1-10 (2019)
Translational Psychiatry
Genetic, epidemiological, and biomarker studies suggest that the immune system is involved in the pathogenesis of bipolar disorder (BD). It has therefore been hypothesized that immune activation of microglia, the resident immune cells of the brain, i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02ebe7b36d5e3495506d67e62e3d8289
https://dspace.library.uu.nl/handle/1874/391579
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8
Telomere quantification in frontal and temporal brain tissue of patients with schizophrenia
Autor: Marjolein A. M. Sneeboer, Jasper C A Broen, Timothy R D J Radstake, Catharina G.K. Wichers, Lot de Witte, René S. Kahn, Yujie He, Hans C. van Mierlo
Publikováno v: Journal of Psychiatric Research, 95, 231. Elsevier Limited
Recent imaging studies have suggested that accelerated aging occurs in schizophrenia. However, the exact cause of these findings is still unclear. In this study we measured telomere length, a marker for cell senescence, in gray and white matter brain
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec05365485bbcff97f888d3cfd28c208
https://dspace.library.uu.nl/handle/1874/355920
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9
Characterization of macrophages from schizophrenia patients
Autor: Paul R Ormel, Miriam E. van Strien, Hans C van Mierlo, Lot D de Witte, René S Kahn, Elly M. Hol, Manja Litjens
Publikováno v: NPJ Schizophrenia, 3(1):41. Nature Publishing Group
NPJ Schizophrenia
npj Schizophrenia, Vol 3, Iss 1, Pp 1-9 (2017)
Genetic, epidemiological and post mortem studies have described an association between schizophrenia (SCZ) and the immune system. Microglia, the tissue-resident macrophages of the brain, not only play an essential role in inflammatory processes, but
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a60896e47c3ede42f95fee9272f4ff
https://hdl.handle.net/20.500.11755/b944a5b0-ee5f-4c04-b05a-f5ed66e193f4
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10
B-cells and schizophrenia : A promising link or a finding lost in translation?
Autor: Hans C. van Mierlo, René S. Kahn, Jasper C A Broen, Lot D. de Witte
Publikováno v: Brain, Behavior, and Immunity, 81, 52. Academic Press Inc.
Recent genetic studies have suggested a potential role for B-cells in the pathogenesis of schizophrenia. Greater insight in the functioning of B-cells in patients with schizophrenia is therefore of importance. In this narrative review we aim to give
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e44a36a4d7b06be3c73462bbafc4a4a3
https://hdl.handle.net/1874/387884
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