Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Hans Bouwmeester"'
Publikováno v:
Particle and Fibre Toxicology, Vol 21, Iss 1, Pp 1-26 (2024)
Abstract Background Micro- and nanoplastics (MNPs) represent one of the most widespread environmental pollutants of the twenty-first century to which all humans are orally exposed. Upon ingestion, MNPs pass harsh biochemical conditions within the gas
Externí odkaz:
https://doaj.org/article/4bdafeb43dc844e0898d5fc24db608db
Autor:
Menno Grouls, Aafke W. F. Janssen, Loes P. M. Duivenvoorde, Guido J. E. J. Hooiveld, Hans Bouwmeester, Meike van der Zande
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Intestinal epithelial cells and the intestinal microbiota are in a mutualistic relationship that is dependent on communication. This communication is multifaceted, but one aspect is communication through compounds produced by the microbiota
Externí odkaz:
https://doaj.org/article/f695a1079d8545a29830e88cc55cc41f
Autor:
Leah M. Thornton Hampton, Hans Bouwmeester, Susanne M. Brander, Scott Coffin, Matthew Cole, Ludovic Hermabessiere, Alvine C. Mehinto, Ezra Miller, Chelsea M. Rochman, Stephen B. Weisberg
Publikováno v:
Microplastics and Nanoplastics, Vol 2, Iss 1, Pp 1-13 (2022)
Abstract To assess the potential risk of microplastic exposure to humans and aquatic ecosystems, reliable toxicity data is needed. This includes a more complete foundational understanding of microplastic toxicity and better characterization of the ha
Externí odkaz:
https://doaj.org/article/9ceca4713f1a45a184070610f4f9898d
Autor:
Scott Coffin, Hans Bouwmeester, Susanne Brander, Pauliina Damdimopoulou, Todd Gouin, Ludovic Hermabessiere, Elaine Khan, Albert A. Koelmans, Christine L. Lemieux, Katja Teerds, Martin Wagner, Stephen B. Weisberg, Stephanie Wright
Publikováno v:
Microplastics and Nanoplastics, Vol 2, Iss 1, Pp 1-30 (2022)
Abstract Microplastics have been documented in drinking water, but their effects on human health from ingestion, or the concentrations at which those effects begin to manifest, are not established. Here, we report on the outcome of a virtual expert w
Externí odkaz:
https://doaj.org/article/43da8badb5fb499ca97fc99dfe8d9b27
Publikováno v:
Antioxidants, Vol 12, Iss 8, p 1544 (2023)
Purpurin is a major anthraquinone present in the roots of Rubia cordifolia (madder). Purpurin is known to activate Nrf2 (Nuclear transcription factor erythroid 2-related factor 2) EpRE (electrophile responsive element) mediated gene expression as a p
Externí odkaz:
https://doaj.org/article/382401b0b7754ea4a1efc052efe60a49
Publikováno v:
Microplastics and Nanoplastics, Vol 2, Iss 1, Pp 1-21 (2022)
Abstract The global production of plastic currently exceeds 300 million tonnes per year. The extensive use of plastics and bad waste management has resulted in the presence of microplastics at different levels in the food production chain. From a che
Externí odkaz:
https://doaj.org/article/6fd40e8743c54429aa9e57161cb91ec2
Autor:
Mathias Busch, Hugo Brouwer, Germaine Aalderink, Gerrit Bredeck, Angela A. M. Kämpfer, Roel P. F. Schins, Hans Bouwmeester
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
Plastic particles in the nanometer range–called nanoplastics–are environmental contaminants with growing public health concern. As plastic particles are present in water, soil, air and food, human exposure via intestine and lung is unavoidable, b
Externí odkaz:
https://doaj.org/article/12d40effc43b4809a3b9b5ae9126970e
Autor:
Sebastin Martin, Laura de Haan, Ignacio Miro Estruch, Kai Moritz Eder, Anne Marzi, Jürgen Schnekenburger, Magda Blosi, Anna Costa, Giulia Antonello, Enrico Bergamaschi, Chiara Riganti, David Beal, Marie Carrière, Olivier Taché, Gary Hutchison, Eva Malone, Lesley Young, Luisa Campagnolo, Fabio La Civita, Antonio Pietroiusti, Stéphanie Devineau, Armelle Baeza, Sonja Boland, Cai Zong, Gaku Ichihara, Bengt Fadeel, Hans Bouwmeester
Publikováno v:
Frontiers in Toxicology, Vol 4 (2022)
Engineered nanomaterials have been found to induce oxidative stress. Cellular oxidative stress, in turn, can result in the induction of antioxidant and detoxification enzymes which are controlled by the nuclear erythroid 2-related factor 2 (NRF2) tra
Externí odkaz:
https://doaj.org/article/876fc2f332f3486997b6cd6f1f9c0aa0
Autor:
Pim de Haan, Milou J. C. Santbergen, Meike van der Zande, Hans Bouwmeester, Michel W. F. Nielen, Elisabeth Verpoorte
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract A novel, integrated, in vitro gastrointestinal (GI) system is presented to study oral bioavailability parameters of small molecules. Three compartments were combined into one hyphenated, flow-through set-up. In the first compartment, a compo
Externí odkaz:
https://doaj.org/article/aa2e8b405d444088bfbbdecd824d68f2
Autor:
Kornphimol Kulthong, Guido J. E. J. Hooiveld, Loes Duivenvoorde, Ignacio Miro Estruch, Victor Marin, Meike van der Zande, Hans Bouwmeester
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Gut-on-chip devices enable exposure of cells to a continuous flow of culture medium, inducing shear stresses and could thus better recapitulate the in vivo human intestinal environment in an in vitro epithelial model compared to static cultu
Externí odkaz:
https://doaj.org/article/9ef7cd120f5546e485ffbc3089283d1b