Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hans Boström"'
Autor:
Martin Knollmann, Hanna Christiansen, Lisa B. Thorell, Hans Boström, James Wiley, Mira-Lynn Chavanon, Fredrik Ulberstad
Publikováno v:
International Journal of Methods in Psychiatric Research
Objective measurements of ADHD symptom levels can be a highly valuable complement to ratings. However, sometimes it is not feasible to bring patients into the clinic/lab for assessment. The aim of the present study was therefore to evaluate the psych
Publikováno v:
Developmental Dynamics. 223:155-162
Platelet-derived growth factors (PDGF) constitute a family of four gene products (PDGF-A-D) acting by means of two receptor tyrosine kinases, PDGFR alpha and beta. Three of the ligands (PDGF-A, -B, and -C) bind to PDGFR alpha with high affinity. Knoc
Autor:
Per Lindahl, Gary C. Franklin, Philippe Soriano, Lars Ährlund-Richter, Christer Betsholtz, Rolf Ohlsson, Mats Hellström, Jeffrey W. Pollard, Pierre Falck, Hans Boström
Publikováno v:
Developmental Biology. 212(1):124-136
PDGFB is a growth factor which is vital for the completion of normal prenatal development. In this study, we report the phenotypic analysis of placentas from mouse conceptuses that lack a functional PDGFB or PDGFRβ gene. Placentas of both types of m
Autor:
Hans Boström, Nicole Wong, Andras Nagy, Patrick P.L. Tam, Hao Ding, Mary L. Marazita, L. Leigh Field, Gou Young Koh, Thomas C. Hart, Christer Betsholtz, Meredith P. O'Rourke, Bonny Tsoi, Xiaoli Wu, Injune Kim, Philippe Soriano
Publikováno v:
Nature genetics. 36(10)
PDGF-C is a member of the platelet-derived growth factor (PDGF) family, which signals through PDGF receptor (PDGFR) alphaalpha and alphabeta dimers. Here we show that Pdgfc(-/-) mice die in the perinatal period owing to feeding and respiratory diffic
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 223(1)
Platelet-derived growth factors (PDGF) constitute a family of four gene products (PDGF-A-D) acting by means of two receptor tyrosine kinases, PDGFR alpha and beta. Three of the ligands (PDGF-A, -B, and -C) bind to PDGFR alpha with high affinity. Knoc
Autor:
Xuri Li, Arne Östman, Carl-Henrik Heldin, Hans Boström, Gudrun Bäckström, Karin Aase, Annica Pontén, L. Karlsson, Alexandra Abramsson, Ulf Eriksson, Philippe Soriano, Hong Li, Mats Hellström, Christer Betsholtz, Kari Alitalo, Marko Uutela
Publikováno v:
Nature cell biology. 2(5)
Platelet-derived growth factors (PDGFs) are important in many types of mesenchymal cell. Here we identify a new PDGF, PDGF-C, which binds to and activates the PDGF alpha-receptor. PDGF-C is activated by proteolysis and induces proliferation of fibrob
Autor:
Alexandra Abramsson, Marcus Fruttiger, Christer Betsholtz, L. Karlsson, Karen Willetts, William D. Richardson, Andrew R. Calver, Claes Henric Bertold, John K. Heath, Anita C. Hall, Hans Boström
Publikováno v:
Europe PubMed Central
There is a class of oligodendrocyte progenitors, called O-2A progenitors, that is characterized by expression of platelet-derived growth factor alpha-receptors (PDGFRα). It is not known whether all oligodendrocytes are derived from these PDGFRα-pro
Publikováno v:
Current Topics in Pathology ISBN: 9783642636035
Platelet-derived growth factors (PGDFs) are 30-kDa dimeric proteins that exert their functions by binding to and activating PDGF receptors in the cell membrane [12, 22]. Two different PDGF monomers exist; the A chain and the B chain, and these may as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37a5d6648bccea85307789c501cc4eac
https://doi.org/10.1007/978-3-642-58456-5_4
https://doi.org/10.1007/978-3-642-58456-5_4
Autor:
Håkan Hedstrand, Karen Willetts, John K. Heath, Jan Törnell, Martin Schalling, Per Levéen, Milos Pekny, Per Lindahl, Hans Boström, Mats Hellström, Mia Nilsson, Samuel Gebre-Medhin, Siri Kurland, Christer Betsholtz, Marcela Pekna
Publikováno v:
Cell. 85(6)
A mouse platelet-derived growth factor A chain (PDGF-A) null allele is shown to be homozygous lethal, with two distinct restriction points, one prenatally before E10 and one postnatally. Postnatally surviving PDGF-A-deficient mice develop lung emphys
Autor:
Kimmo Porkka, Bengt Simonsson, Marie Schaffer, Irina Golovleva, Morten Andersen, Johann Lanng Nielsen, Thoas Fioretos, Jon Jonasson, Tuija Lundan, Aleksandra Silye, M. Lindlöf, Mats Irgen Olsen, Eeva-Riitta Savolainen, Magnus K. Magnusson, Hans Boström, Gisela Barbany, Vesa Juvonen, Niels Pallisgaard, Veli Kairisto, Henrik Hjorth-Hansen
Publikováno v:
Blood. 110:4559-4559
Measuring the level of BCR-ABL transcripts by real-time quantitative polymerase chain reaction (RQ-PCR) has been shown to be a highly sensitive and specific method for evaluating residual disease burden in chronic myeloid leukemia (CML). In the IRIS