Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Hans Blokzijl"'
Autor:
Magnolia Martínez-Aguilar, María Camila Trillos-Almanza, Justina C. Wolters, Manon Buist-Homan, TransplantLines Investigators, Frederike van Vilsteren, Hans Blokzijl, Han Moshage
Publikováno v:
Exploration of Digestive Diseases, Vol 3, Iss 2, Pp 143-162 (2024)
Aim: Extracellular vesicles (EVs) have gained significant attention for their diagnostic and therapeutic potential in various diseases, including liver disorders. This study focuses on optimizing the isolation and characterization of small EVs from p
Externí odkaz:
https://doaj.org/article/fac795c2bb8b4781962d863728fd9087
Autor:
Maria Camila Trillos-Almanza, Magnolia Martinez-Aguilar, Johanna C. Arroyave-Ospina, Frederike van Vilsteren, Hans Blokzijl, Han Moshage
Publikováno v:
Muscles, Vol 3, Iss 1, Pp 71-87 (2024)
This comprehensive review focuses on the dynamics of branched-chain amino acids (BCAAs) metabolism and its clinical implications in chronic liver disease, with emphasis on the emerging concept of muscle–liver crosstalk. BCAAs, indispensable for pro
Externí odkaz:
https://doaj.org/article/da692d15f16d4affae7549d8014fc3cb
Autor:
Chikako Endo, MD, Bianca Lascaris, MD, Isabel M. A. Brüggenwirth, MD, PhD, Jan Roggeveld, MBO, Hans Blokzijl, MD, PhD, Vincent E. de Meijer, MD, PhD, M. H. Edwina Doting, MD, PhD, Robert J. Porte, MD, PhD
Publikováno v:
Transplantation Direct, Vol 10, Iss 7, p e1664 (2024)
Background. Ex situ machine perfusion is increasingly used to preserve and assess donor livers before transplantation. Compared with traditional static cold storage (SCS), machine perfusion exposes livers to an additional risk of microbial contaminat
Externí odkaz:
https://doaj.org/article/26bc4ba3f3d242178b8ecb904c6ef577
Autor:
J. Casper Swarte, Tim J. Knobbe, Johannes R. Björk, Ranko Gacesa, Lianne M. Nieuwenhuis, Shuyan Zhang, Arnau Vich Vila, Daan Kremer, Rianne M. Douwes, Adrian Post, Evelien E. Quint, Robert A. Pol, Bernadien H. Jansen, TransplantLines investigators, Martin H. de Borst, Vincent E. de Meijer, Hans Blokzijl, Stefan P. Berger, Eleonora A. M. Festen, Alexandra Zhernakova, Jingyuan Fu, Hermie J. M. Harmsen, Stephan J. L. Bakker, Rinse K. Weersma
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Kidney transplant recipients (KTR) have impaired health-related quality of life (HRQoL) and suffer from intestinal dysbiosis. Increasing evidence shows that gut health and HRQoL are tightly related in the general population. Here, we investi
Externí odkaz:
https://doaj.org/article/cdeb8a6b39384ab38c6f1bc5cddf08f1
Autor:
Isabel M.A. Brüggenwirth, Veerle A. Lantinga, Bianca Lascaris, Adam M. Thorne, Mark Meerdink, Ruben H. de Kleine, Hans Blokzijl, Aad P. van den Berg, Koen M.E.M. Reyntjens, Ton Lisman, Robert J. Porte, Vincent E. de Meijer, Cyril Moers, Diethard Monbaliu, Sijbrand H. Hofker, Jan Bottema, Hildegaard S. Franke, Marieke T. de Boer, Anne Loes van den Boom, Carlijn I. Buis, Suomi M.G. Fouraschen, Frederik J.H. Hoogwater, Joost M. Klaase, Ruben H.J. de Kleine, Maarten W. Nijkamp, A. Michel Rayar, Frans J.C. Cuperus, Frans van der Heide, Frederike G.I. van Vilsteren, Ilhama F. Abbasova, Meine H. Fernhout, Peter Meyer, Ernesto R.R. Muskiet, Jaap J. Vos, Miriam Zeillemaker, Martijn P.D. Haring, Carol C. Pamplona, Vivianne Veenma, Otto B. van Leeuwen, Silke B. Bodewes, Jelle Adelmeijer, Janneke Wiersema-Buist, Marius van den Heuvel
Publikováno v:
EClinicalMedicine, Vol 68, Iss , Pp 102411- (2024)
Summary: Background: Liver transplantation is traditionally performed around the clock to minimize organ ischemic time. However, the prospect of prolonging preservation times holds the potential to streamline logistics and transform liver transplanta
Externí odkaz:
https://doaj.org/article/29158e4bdd724fc08b40eb8e81f7654a
Autor:
Defu Kong, Apostolos Mourtzinos, Janette Heegsma, Hans Blokzijl, Vincent E. de Meijer, Klaas Nico Faber
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Background and aim Liver fibrosis is prevalent among chronic diseases of the liver and represents a major health burden worldwide. Growth differentiation factor 7 (GDF7), a member of the TGFβ protein superfamily, has been recently investiga
Externí odkaz:
https://doaj.org/article/247aa6197a6a4e9e824f186fdb96d24d
Autor:
Maria Camila Trillos-Almanza, Mateo Chvatal-Medina, Margery A. Connelly, Han Moshage, TransplantLines Investigators, Stephan J. L. Bakker, Vincent E. de Meijer, Hans Blokzijl, Robin P. F. Dullaart
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 6031 (2024)
Liver transplant recipients (LTRs) have lower long-term survival rates compared with the general population. This underscores the necessity for developing biomarkers to assess post-transplantation mortality. Here we compared plasma trimethylamine-N-o
Externí odkaz:
https://doaj.org/article/f7ed13eb67a7426ca1b6846ce5b0ab99
Autor:
Hans Blokzijl, Vincent E de Meijer, Rienk Dekker, Joost M Klaase, Coby Annema, Bart C Bongers, Allard G Wijma, Job AM van der Palen, Frans JC Cuperus
Publikováno v:
BMJ Open, Vol 14, Iss 1 (2024)
Introduction Patients with end-stage liver disease awaiting orthotopic liver transplantation (OLT) are generally classified as frail due to disease-related malnutrition and a progressive decline in musculoskeletal and aerobic fitness, which is associ
Externí odkaz:
https://doaj.org/article/fc04d0aa3aa0438ab94bca1ea965230d
Autor:
Zongmei Wu, Mengmeng Xia, Sandra Serna Salas, Maria Camila Trillos-Almanza, Magnolia Martinez Aguilar, Johanna C. Arroyave-Ospina, Junyu Wang, Marco Arrese, Svenja Sydor, Lars P. Bechmann, Frederike GI van Vilsteren, Hans Blokzijl, Han Moshage
Publikováno v:
Exploration of Digestive Diseases, Vol 1, Iss 1, Pp 4-20 (2022)
The prevalence of metabolic dysfunction-associated fatty liver disease (MAFLD) is increasing rapidly worldwide due to the obesity epidemic. Advanced stages of the MAFLD, such as non-alcoholic steatohepatitis (NASH) with advanced fibrosis or cirrhosis
Externí odkaz:
https://doaj.org/article/ea74b7ba35244121ac69087233bb96a4
Autor:
Maria Camila Trillos-Almanza, Hanna Wessel, Magnolia Martínez-Aguilar, Eline H. van den Berg, Rianne M. Douwes, Han Moshage, Margery A. Connelly, Stephan J. L. Bakker, Vincent E. de Meijer, Robin P. F. Dullaart, Hans Blokzijl
Publikováno v:
Biomolecules, Vol 13, Iss 5, p 824 (2023)
Decreased circulating branched chain amino acids (BCAA) represent a prominent change in amino acid profiles in patients with end-stage liver disease (ESLD). These alterations are considered to contribute to sarcopenia and hepatic encephalopathy and m
Externí odkaz:
https://doaj.org/article/52adda2308304a418651fd6ac5bacbda