Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Hans Nohl"'
Autor:
Klaus Stolze, Hans Nohl
This chapter discusses formation of methemoglobin (MetHb) and free radicals in erythrocytes. Liganding of dioxygen to hemoglobin is associated with the dislocation of an electron from the iron atom orbital to the molecular orbital of oxygen. The smal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::490619945f219f4e6bbf56c6f22cabab
https://doi.org/10.1201/9780203747605-9
https://doi.org/10.1201/9780203747605-9
Publikováno v:
Arzneimittelforschung. 49:335-343
Pangamic acid (6-O-(dimethylaminoacetyl)-D-gluconic acid) has been detected 1938 and described as a natural, universally occurring substance with multiple biological and medical functions. In this respect pangamic acid has been worldwide on the marke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d94d30f49b3bc0c673ca26e8624afe5
https://doi.org/10.1055/s-0031-1300424
https://doi.org/10.1055/s-0031-1300424
Autor:
Haitao Li, Mark T. Gladwin, Anny Slama-Schwok, Anatoly F. Vanin, Jon O. Lundberg, Tienush Rassaf, Alexandre Samouilov, Eddie Weitzberg, Martin Feelisch, Ron Mason, Daniel B. Kim-Shapiro, Hans Nohl, Neil Hogg, Jay L. Zweier, Sruti Shiva, Soheyl Bahrami, Andrey V. Kozlov, Ernst E. van Faassen, Malte Kelm
Publikováno v:
Medicinal Research Reviews
Medicinal Research Reviews, Wiley, 2009, 29 (5), pp.683-741. ⟨10.1002/med.20151⟩
Medicinal Research Reviews, Wiley, 2009, 29 (5), pp.683-741. ⟨10.1002/med.20151⟩
International audience; In this review we consider the effects of endogenous and pharmacological levels of nitrite under conditions of hypoxia. In humans, the nitrite anion has long been considered as metastable intermediate in the oxidation of nitri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::957dc53d10379cb6de4355ebf157d5d0
https://doi.org/10.1002/med.20151
https://doi.org/10.1002/med.20151
Publikováno v:
Bioorganic & Medicinal Chemistry. 15:2827-2836
The spin trapping behavior of several ethyl-substituted EMPO derivatives, cis- and trans-5-ethoxycarbonyl-3-ethyl-5-methyl-pyrroline N-oxide (3,5-EEMPO), 5-ethoxycarbonyl-4-ethyl-5-methyl-pyrroline N-oxide (4,5-EEMPO), cis- and trans-5-ethoxycarbonyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::636321773d4c04f936539ebea9afbb19
https://doi.org/10.1016/j.bmc.2007.02.025
https://doi.org/10.1016/j.bmc.2007.02.025
Autor:
Manfred Gemeiner, Wolfgang Öhlinger, Soheyl Bahrami, Katrin Staniek, Christina Piskernik, Hans Nohl, Susanne Haindl, Heinz Redl, Ingrid Miller, Lars Gille, Andrey V. Kozlov
Publikováno v:
Biochemical and Biophysical Research Communications. 352:91-96
In this study, we determined functional integrity and reactive oxygen species generation in mitochondria and endoplasmic reticulum in liver of rats subjected to endotoxic shock to clarify whether intracellular reactive oxygen species (ROS) destabiliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4410f5ec7b54d645b6770bb65e9bbca0
https://doi.org/10.1016/j.bbrc.2006.10.180
https://doi.org/10.1016/j.bbrc.2006.10.180
Publikováno v:
Biochemical Pharmacology. 71:1589-1601
Alpha-tocopherol (Toc) is an efficient lipophilic antioxidant present in all mammalian lipid membranes. This chromanol is metabolized by two different pathways: excessive dietary Toc is degraded in the liver by side chain oxidation, and Toc acting as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20302205c99f6666e3af9b2657dbb324
https://doi.org/10.1016/j.bcp.2006.02.012
https://doi.org/10.1016/j.bcp.2006.02.012
Publikováno v:
Bioorganic & Medicinal Chemistry. 14:3368-3376
In order to develop spin traps with an optimal ratio between hydrophilic and lipophilic properties, low toxicity, and high stability of spin adducts (especially with superoxide radicals), several EMPO-derived spin traps have recently been synthesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bd8e294e34de1ee5e05e9fd92c2aee3
https://doi.org/10.1016/j.bmc.2005.12.051
https://doi.org/10.1016/j.bmc.2005.12.051
Autor:
Hans Nohl, Wolfgang Öhlinger, Christina Piskernik, Susanne Haindl, Andrey V. Kozlov, Katrin Staniek, Redl H, S. Bahrami, Lars Gille
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 290:G543-G549
This study was designed to clarify whether mitochondrial function/dysfunction and reactive oxygen species (ROS) production have a temporal relationship with organ failure during endotoxic shock. Adult male Sprague-Dawley rats were divided into three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1de36d6afa85b4d38decca71441510e
https://doi.org/10.1152/ajpgi.00331.2005
https://doi.org/10.1152/ajpgi.00331.2005
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 16:541-546
Free radicals are involved in different regulatory and pathological processes. The formation of superoxide in living cells or whole organisms is of major interest. ESR spin trapping allows identification of the radicals if proper spin traps are avail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed15a82ac0520f8af91290c091711dc
https://doi.org/10.1016/j.bmcl.2005.10.060
https://doi.org/10.1016/j.bmcl.2005.10.060
Publikováno v:
Free Radical Research. 40:513-521
Although flavonoid molecules have attracted considerable interest in recent years because of their antioxidant effect, there are considerable differences in their chemical properties. Electron paramagnetic resonance (EPR) spectroscopy was used to com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcfb57f4f6e62a9d37fd18bb215c0363
https://doi.org/10.1080/10715760600602894
https://doi.org/10.1080/10715760600602894