Zobrazeno 1 - 10
of 548
pro vyhledávání: '"Hans Kreipe"'
Autor:
Malte Gronewold, Isabel Grote, Stephan Bartels, Henriette Christgen, Leonie D Kandt, Maria Jose Brito, Gàbor Cserni, Maximilian E Daemmrich, Franz Fogt, Burkhard M Helmke, Natalie terHoeve, Corinna Lang‐Schwarz, Michael Vieth, Axel Wellmann, Elna Kuehnle, Ulf Kulik, Gesa Riedel, Tanja Reineke‐Plaass, Ulrich Lehmann, Thijs Koorman, Patrick WB Derksen, Hans Kreipe, Matthias Christgen
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 2, Pp n/a-n/a (2024)
Abstract Invasive lobular carcinoma (ILC) is a special breast cancer type characterized by noncohesive growth and E‐cadherin loss. Focal activation of P‐cadherin expression in tumor cells that are deficient for E‐cadherin occurs in a subset of
Externí odkaz:
https://doaj.org/article/17f39eb0bc1f4bccb3a68ec3ef1af3e8
Autor:
Stephan Bartels, Isabel Grote, Madeleine Wagner, Jannik Boog, Elisa Schipper, Tanja Reineke‐Plaass, Hans Kreipe, Ulrich Lehmann
Publikováno v:
Cancer Medicine, Vol 12, Iss 16, Pp 16707-16715 (2023)
Abstract Background Microsatellite instability (MSI) occurs in several cancer types and is commonly used for prognosis and as a predictive biomarker for immune checkpoint therapy. Methods We analyzed n = 263 formalin‐fixed paraffin‐embedded (FFPE
Externí odkaz:
https://doaj.org/article/539e91d7684241389afa775689e1d8e9
Autor:
Olaf Neumann, Ulrich Lehmann, Stephan Bartels, Nicole Pfarr, Thomas Albrecht, Katharina Ilm, Jens Christmann, Anna‐Lena Volckmar, Hannah Goldschmid, Martina Kirchner, Michael Allgäuer, Maria Walker, Hans Kreipe, Andrea Tannapfel, Wilko Weichert, Peter Schirmacher, Daniel Kazdal, Albrecht Stenzinger
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 9, Iss 2, Pp 100-107 (2023)
Abstract Intrahepatic cholangiocarcinoma harbours druggable genetic lesions including FGFR2 gene fusions. Reliable and accurate detection of these fusions is becoming a critical component of the molecular work‐up, but real‐world data on the perfo
Externí odkaz:
https://doaj.org/article/766fefd6743746f48f23bf3da053da40
Autor:
Cornelia Kolberg-Liedtke, Friedrich Feuerhake, Madlen Garke, Matthias Christgen, Ronald Kates, Eva Maria Grischke, Helmut Forstbauer, Michael Braun, Mathias Warm, John Hackmann, Christoph Uleer, Bahriye Aktas, Claudia Schumacher, Sherko Kuemmel, Rachel Wuerstlein, Monika Graeser, Ulrike Nitz, Hans Kreipe, Oleg Gluz, Nadia Harbeck
Publikováno v:
Breast Cancer Research, Vol 24, Iss 1, Pp 1-13 (2022)
Abstract Background Higher density of stromal tumor-infiltrating lymphocytes (sTILs) at baseline has been associated with increased rates of pathological complete response (pCR) after neoadjuvant chemotherapy (NACT) in triple-negative breast cancer (
Externí odkaz:
https://doaj.org/article/8e767ca38fb44eb2b85c5566cfa49c03
Autor:
Matthias Christgen, Leonie Donata Kandt, Wiebke Antonopoulos, Stephan Bartels, Mieke R VanBockstal, Martin Bredt, Maria Jose Brito, Henriette Christgen, Cecile Colpaert, Bálint Cserni, Gábor Cserni, Maximilian E Daemmrich, Raihanatou Danebrock, Franceska Dedeurwaerdere, Carolien HM vanDeurzen, Ramona Erber, Christine Fathke, Henning Feist, Maryse Fiche, Claudia Aura Gonzalez, Natalie D terHoeve, Loes Kooreman, Till Krech, Glen Kristiansen, Janina Kulka, Florian Laenger, Marcel Lafos, Ulrich Lehmann, Maria Dolores Martin‐Martinez, Sophie Mueller, Enrico Pelz, Mieke Raap, Alberto Ravarino, Tanja Reineke‐Plaass, Nora Schaumann, Anne‐Marie Schelfhout, Maxim DeSchepper, Jerome Schlue, Koen Van de Vijver, Wim Waelput, Axel Wellmann, Monika Graeser, Oleg Gluz, Sherko Kuemmel, Ulrike Nitz, Nadia Harbeck, Christine Desmedt, Giuseppe Floris, Patrick WB Derksen, Paul J vanDiest, Anne Vincent‐Salomon, Hans Kreipe
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 8, Iss 2, Pp 191-205 (2022)
Abstract Invasive lobular breast carcinoma (ILC) is the second most common breast carcinoma (BC) subtype and is mainly driven by loss of E‐cadherin expression. Correct classification of BC as ILC is important for patient treatment. This study asses
Externí odkaz:
https://doaj.org/article/315199064a574f7f8e979a65ce71d4f6
Autor:
Isabel Grote, Stephan Bartels, Leonie Kandt, Laura Bollmann, Henriette Christgen, Malte Gronewold, Mieke Raap, Ulrich Lehmann, Oleg Gluz, Ulrike Nitz, Sherko Kuemmel, Christine zuEulenburg, Michael Braun, Bahriye Aktas, Eva‐Maria Grischke, Claudia Schumacher, Kerstin Luedtke‐Heckenkamp, Ronald Kates, Rachel Wuerstlein, Monika Graeser, Nadia Harbeck, Matthias Christgen, Hans Kreipe
Publikováno v:
Cancer Medicine, Vol 10, Iss 23, Pp 8581-8594 (2021)
Abstract Background Whereas the genomic landscape of endocrine‐resistant breast cancer has been intensely characterized in previously treated cases with local or distant recurrence, comparably little is known about genomic alterations conveying pri
Externí odkaz:
https://doaj.org/article/2c544d649b024c5bbd721b91d7f7c740
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 14 (2022)
Ki67 represents an immunohistochemical nuclear localized marker that is widely used in surgical pathology. Nuclear immunoreactivity for Ki67 indicates that cells are cycling and are in G1- to S-phase. The percentage of Ki67-positive tumor cells (Ki67
Externí odkaz:
https://doaj.org/article/e953feb7e1e744398b81dbc5a3f45941
Autor:
Martin Radner, Jana Lisa vanLuttikhuizen, Stephan Bartels, Janin Bublitz, Isabel Grote, Luisa Rieger, Henriette Christgen, Helge Stark, Christopher Werlein, Marcel Lafos, Doris Steinemann, Ulrich Lehmann, Matthias Christgen, Hans Kreipe
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 3, Pp 220-232 (2021)
Abstract Microglandular adenosis (MGA) represents a rare neoplasm of the mammary gland, which in a subset of cases may be associated with triple‐negative breast cancer (BC). The biology of MGA is poorly understood. In this study, eight MGA cases (n
Externí odkaz:
https://doaj.org/article/f37a43b2ff0543ebad187f8cfc8d9eaa
Publikováno v:
Fetal and Pediatric Pathology. :1-12
Autor:
Isabel Grote, Stephan Bartels, Henriette Christgen, Martin Radner, Malte Gronewold, Leonie Kandt, Mieke Raap, Ulrich Lehmann, Oleg Gluz, Monika Graeser, Sherko Kuemmel, Ulrike Nitz, Nadia Harbeck, Hans Kreipe, Matthias Christgen
Publikováno v:
Modern Pathology. 35:1804-1811
Invasive lobular breast cancer (ILC) is a special breast cancer (BC) subtype and is mostly hormone receptor (HR)-positive and ERBB2 non-amplified. Endocrine therapy restrains tumor proliferation and is the mainstay of lobular BC treatment. Mutation o