Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Hans‐Jürgen Thiesen"'
Publikováno v:
Biomolecules, Vol 14, Iss 4, p 454 (2024)
Investigations on binding strength differences of non-covalent protein complex components were performed by mass spectrometry. T4 fibritin foldon (T4Ff) is a well-studied miniprotein, which together with its biotinylated version served as model syste
Externí odkaz:
https://doaj.org/article/4c6db1ae968f4673870967f849eb1810
Publikováno v:
BMC Molecular and Cell Biology, Vol 20, Iss 1, Pp 1-23 (2019)
Abstract Background ZNF746 and ZNF777 belong to a subset of the large Krüppel-associated box (KRAB) zinc finger (ZNF) transcription factor family. They contain, like four other members in human, an additional conserved domain, the “domain of unkno
Externí odkaz:
https://doaj.org/article/9397b2b31ab14f28b829ada5afa0bf97
Autor:
Michael Hecker, Nina Boxberger, Nicole Illner, Brit Fitzner, Ina Schröder, Alexander Winkelmann, Ales Dudesek, Stefanie Meister, Dirk Koczan, Peter Lorenz, Hans-Jürgen Thiesen, Uwe Klaus Zettl
Publikováno v:
PLoS Genetics, Vol 15, Iss 2, p e1007961 (2019)
Genome-wide association studies have identified more than 200 genetic variants to be associated with an increased risk of developing multiple sclerosis (MS). Still, little is known about the causal molecular mechanisms that underlie the genetic contr
Externí odkaz:
https://doaj.org/article/1e24d0888dac4d06af0f5494b1137d0a
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e87609 (2014)
The Krüppel-associated box (KRAB) domain interacts with the nuclear hub protein TRIM28 to initiate or mediate chromatin-dependent processes like transcriptional repression, imprinting or suppression of endogenous retroviruses. The prototype KRAB dom
Externí odkaz:
https://doaj.org/article/5f1ed47545c04ca39c205cf7377b9f95
Autor:
Mitja Luštrek, Peter Lorenz, Michael Kreutzer, Zilliang Qian, Felix Steinbeck, Di Wu, Nadine Born, Bjoern Ziems, Michael Hecker, Miri Blank, Yehuda Shoenfeld, Zhiwei Cao, Michael O Glocker, Yixue Li, Georg Fuellen, Hans-Jürgen Thiesen
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78605 (2013)
Epitope-antibody-reactivities (EAR) of intravenous immunoglobulins (IVIGs) determined for 75,534 peptides by microarray analysis demonstrate that roughly 9% of peptides derived from 870 different human protein sequences react with antibodies present
Externí odkaz:
https://doaj.org/article/c27deddd06164467b976df3714dca77b
Autor:
Marta Rizzi, Rolf Knoth, Christiane S Hampe, Peter Lorenz, Marie-Lise Gougeon, Brigitte Lemercier, Nils Venhoff, Francesca Ferrera, Ulrich Salzer, Hans-Jürgen Thiesen, Hans-Hartmut Peter, Ulrich A Walker, Hermann Eibel
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10838 (2010)
Stiff person syndrome (SPS) is a rare, neurological disorder characterized by sudden cramps and spasms. High titers of enzyme-inhibiting IgG autoantibodies against the 65 kD isoform of glutamic acid decarboxylase (GAD65) are a hallmark of SPS, implic
Externí odkaz:
https://doaj.org/article/ad26bfdf619f451fadc46394dca96a25
Autor:
Vassilis Aidinis, Piero Carninci, Maria Armaka, Walter Witke, Vaggelis Harokopos, Norman Pavelka, Dirk Koczan, Christos Argyropoulos, Maung-Maung Thwin, Steffen Möller, Kazunori Waki, Ponnampalam Gopalakrishnakone, Paola Ricciardi-Castagnoli, Hans-Jürgen Thiesen, Yoshihide Hayashizaki, George Kollias
Publikováno v:
PLoS Genetics, Vol 1, Iss 5 (2005)
Externí odkaz:
https://doaj.org/article/dd60ea27e4e34ecda68bb79c9d1dfd57
Autor:
Vassilis Aidinis, Piero Carninci, Maria Armaka, Walter Witke, Vaggelis Harokopos, Norman Pavelka, Dirk Koczan, Christos Argyropoulos, Maung-Maung Thwin, Steffen Möller, Kazunori Waki, Ponnampalam Gopalakrishnakone, Paola Ricciardi-Castagnoli, Hans-Jürgen Thiesen, Yoshihide Hayashizaki, George Kollias
Publikováno v:
PLoS Genetics, Vol 1, Iss 4, p e48 (2005)
Rheumatoid arthritis is a chronic inflammatory disease with a high prevalence and substantial socioeconomic burden. Despite intense research efforts, its aetiology and pathogenesis remain poorly understood. To identify novel genes and/or cellular pat
Externí odkaz:
https://doaj.org/article/10ed93b4fa424923994fb2a12790a29f
Autor:
Maximilian Scherf, Bright D. Danquah, Cornelia Koy, Peter Lorenz, Felix Steinbeck, Andrei Neamtu, Hans‐Jürgen Thiesen, Michael O. Glocker
Publikováno v:
Chembiochem : a European journal of chemical biology. 23(20)
Accurate formation of antibody-antigen complexes has been relied on in both, multitudes of scientific projects and ample therapeutic and diagnostic applications. Mass spectrometrically determined dissociation behavior of immune complexes with the ant
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 3; Pages: 1072
International Journal of Molecular Sciences, Vol 23, Iss 1072, p 1072 (2022)
International Journal of Molecular Sciences, Vol 23, Iss 1072, p 1072 (2022)
Krüppel-associated box (KRAB) zinc finger proteins are a large class of tetrapod transcription factors that usually exert transcriptional repression through recruitment of TRIM28/KAP1. The evolutionary root of modern KRAB domains (mKRAB) can be trac