Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Hans, de Looper"'
Autor:
Wei Zhang, Emanuele Gioacchino, Cansu Koyunlar, Joke Zink, Hans de Looper, Kirsten J. Gussinklo, Remco Hoogenboezem, Dennis Bosch, Eric Bindels, Ivo P. Touw, Emma de Pater
Publikováno v:
HemaSphere, Vol 7, p e94325dc (2023)
Externí odkaz:
https://doaj.org/article/30747f125c114725a39d2c81bfa3fc96
Autor:
Cansu Koyunlar, Emanuele Gioacchino, Disha Vadgama, Hans de Looper, Joke Zink, Mariette N. D. ter Borg, Remco Hoogenboezem, Marije Havermans, Mathijs A. Sanders, Eric Bindels, Elaine Dzierzak, Ivo P. Touw, Emma de Pater
Publikováno v:
Blood advances, 7(10), 2082-2093. American Society of Hematology
The first hematopoietic stem cells (HSCs) are formed through endothelial-to-hematopoietic transition (EHT) during embryonic development. The transcription factor GATA2 is a crucial regulator of EHT and HSC function throughout life. Because patients w
Autor:
Jennifer L. Hope, Manzhi Zhao, Christopher J. Stairiker, Caoimhe H. Kiernan, Alison J. Carey, Yvonne M. Mueller, Marjan van Meurs, Inge Brouwers-Haspels, Dennis C. Otero, Eun-Ah Bae, Hannah A. Faso, Alex Maas, Hans de Looper, Paolo M. Fortina, Isidore Rigoutsos, Linda M. Bradley, Stefan J. Erkeland, Peter D. Katsikis
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950), 208(3), 603-617. American Association of Immunologists
MicroRNAs (miRNAs/miRs) are small, endogenous noncoding RNAs that are important post-transcriptional regulators with clear roles in the development of the immune system and immune responses. Using miRNA microarray profiling, we characterized the expr
Autor:
Cansu Koyunlar, Emanuele Gioacchino, Disha Vadgama, Hans de Looper, Joke Zink, Remco Hoogenboezem, Marije Havermans, Eric Bindels, Elaine Dzierzak, Ivo P Touw, Emma de Pater
The first hematopoietic stem cells (HSCs) are formed through endothelial-to-hematopoietic transition (EHT) events during embryonic development. The transcription factor GATA2 is a crucial regulator of EHT and HSC function throughout life. Because GAT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aae88453892adb32afafd67dc3877a5
https://doi.org/10.1101/2022.03.24.485642
https://doi.org/10.1101/2022.03.24.485642
Autor:
Emanuele Gioacchino, Wei Zhang, Cansu Koyunlar, Joke Zink, Hans de Looper, Kirsten J. Gussinklo, Remco Hoogenboezem, Dennis Bosch, Eric Bindels, Ivo P. Touw, Emma de Pater
The transcription factor GATA2 has pivotal roles in hematopoiesis. Germline GATA2 mutations in patients result in GATA2 haploinsufficiency syndrome characterized by immunodeficiency, bone marrow failure, and predispositions to myelodysplastic syndrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49378a3a60c0e865c3f6b9414749af36
https://doi.org/10.1101/2021.10.29.466416
https://doi.org/10.1101/2021.10.29.466416
Autor:
Cansu Koyunlar, Hans de Looper, Dennis Bosch, Rui Monteiro, Emma de Pater, Joke Zink, Ivo P. Touw, Christopher B. Mahony, Madelon de Jong, Martin E. van Royen, Tomasz Dobrzycki, Eric Bindels, Remco Hoogenboezem, Paulina M. H. van Strien, Kirsten Gussinklo, Pim J. French, Emanuele Gioacchino
Publikováno v:
Blood advances, 5(13), 2687-2700. American Society of Hematology
Blood Adv
Blood Adv
The differentiation of hematopoietic stem cells (HSCs) is tightly controlled to ensure a proper balance between myeloid and lymphoid cell output. GATA2 is a pivotal hematopoietic transcription factor required for generation and maintenance of HSCs. G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2392ec675cf9bc0fb3b280f84aed1a82
https://pure.eur.nl/en/publications/24190a85-ae08-4ceb-901f-766bd542a9aa
https://pure.eur.nl/en/publications/24190a85-ae08-4ceb-901f-766bd542a9aa
Autor:
Emma de Pater, Cansu Kayunlar, Emanuele Gioacchino, Hans de Looper, Mariette ter Borg, Joke Zink, Remco Hoogenboezem, Mathijs Sanders, Eric Bindels, Ivo Touw
Publikováno v:
Experimental Hematology. 111:S79
Autor:
Mehrnaz Ghazvini, Eric M.J. Bindels, Ivo P. Touw, Paulina M. H. van Strien, Vincent H.J. van der Velden, Remco Hoogenboezem, Dennis Bosch, Pier G. Mastroberardino, Emma de Pater, Hans de Looper, Onno Roovers, Sander Barnhoorn, Patricia A. Olofsen
Publikováno v:
Blood Adv
Blood advances, 5(3), 775-786. American Society of Hematology
Blood advances, 5(3), 775-786. American Society of Hematology
Mutations in ELANE cause severe congenital neutropenia (SCN), but how they affect neutrophil production and contribute to leukemia predisposition is unknown. Neutropenia is alleviated by CSF3 (granulocyte colony-stimulating factor) therapy in most ca
Autor:
Jennifer L, Hope, Manzhi, Zhao, Christopher J, Stairiker, Caoimhe H, Kiernan, Alison J, Carey, Yvonne M, Mueller, Marjan, van Meurs, Inge, Brouwers-Haspels, Dennis C, Otero, Eun-Ah, Bae, Hannah A, Faso, Alex, Maas, Hans, de Looper, Paolo M, Fortina, Isidore, Rigoutsos, Linda M, Bradley, Stefan J, Erkeland, Peter D, Katsikis
Publikováno v:
J Immunol
MicroRNAs (miRNAs/miRs) are small, endogenous noncoding RNAs that are important post-transcriptional regulators with clear roles in the development of the immune system and immune responses. Using miRNA microarray profiling, we characterized the expr
Autor:
Ivo P. Touw, Onno Roovers, Torsten Haferlach, Eric M.J. Bindels, Julia C. Obenauer, Emma de Pater, Szabolcs Fatrai, Remco Hoogenboezem, Rebekka K. Schneider, Paulina M. H. van Strien, Hans de Looper, Mehrnaz Ghazvini, Michael P.W.M. Vermeulen, Claudia A.J. Erpelinck-Verschueren, Joop H. Jansen, Patricia A. Olofsen
Publikováno v:
Cell Reports Medicine, 1, 5
Cell Reports Medicine, 1
Cell Reports Medicine, 1(5):100074. Cell Press
Cell Reports Medicine
Cell Reports Medicine, Vol 1, Iss 5, Pp 100074-(2020)
Cell Reports Medicine, 1
Cell Reports Medicine, 1(5):100074. Cell Press
Cell Reports Medicine
Cell Reports Medicine, Vol 1, Iss 5, Pp 100074-(2020)
Summary Severe congenital neutropenia (SCN) patients treated with CSF3/G-CSF to alleviate neutropenia frequently develop acute myeloid leukemia (AML). A common pattern of leukemic transformation involves the appearance of hematopoietic clones with CS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8e8185773d4b782f90b97173a3e346d
https://hdl.handle.net/2066/229624
https://hdl.handle.net/2066/229624