Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hans, Reinke"'
Publikováno v:
PLoS Biology, Vol 9, Iss 2, p e1000595 (2011)
The mammalian circadian clock uses interlocked negative feedback loops in which the heterodimeric basic helix-loop-helix transcription factor BMAL1/CLOCK is a master regulator. While there is prominent control of liver functions by the circadian cloc
Externí odkaz:
https://doaj.org/article/c2ee8c98031d4142ad02218a776e5d72
Autor:
Gad Asher, Hans Reinke
Publikováno v:
Nature reviews. Molecular cell biology. 20(4)
Humans, like all mammals, partition their daily behaviour into activity (wakefulness) and rest (sleep) phases that differ largely in their metabolic requirements. The circadian clock evolved as an autonomous timekeeping system that aligns behavioural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e95e7a8c810432026333f1a10f4c433
https://pubmed.ncbi.nlm.nih.gov/30635659
https://pubmed.ncbi.nlm.nih.gov/30635659
Autor:
Hussam Ibrahim, Faiza Kalfalah, Anna-Lena Grothoff, Hans Reinke, Valerie Rudenko, Anja Stefanski, Christina Buschhaus, Niklas Berleth, Kai Stühler, Philipp Reus, Anna Katharina Mundorf, Björn Stork
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 3787, p 3787 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 7
International Journal of Molecular Sciences
Volume 22
Issue 7
Repressor protein period (PER) complexes play a central role in the molecular oscillator mechanism of the mammalian circadian clock. While the main role of nuclear PER complexes is transcriptional repression, much less is known about the functions of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c4cce7f3a59a3537c66b341a61ac3e3
https://doi.org/10.3390/ijms22073787
https://doi.org/10.3390/ijms22073787
Autor:
Gad Asher, Hans Reinke
Publikováno v:
Hepatology. 67:441-443
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20438982af0925c0e9435fff69a0048d
https://doi.org/10.1002/hep.29506
https://doi.org/10.1002/hep.29506
Publikováno v:
Neuroendocrinology. 103:605-615
Introduction: Heat shock factor 1 (HSF1) is a ubiquitous heat-sensitive transcription factor that mediates heat shock protein transcription in response to cellular stress, such as increased temperature, in order to protect the organism against misfol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d704c09c46fb26ce088235275d80008f
https://doi.org/10.1159/000441947
https://doi.org/10.1159/000441947
Autor:
Karl Köhrer, Hans Reinke, Helmut Hanenberg, Charlotte von Gall, Katja Pexa, Roland P. Piekorz, Dennis Stibane, Madhurendra Singh, Constanze Wiek, Hakima Ezzahoini, Antje Lindecke, Alexander Lang, Fabian Kuck, Linda Janke, Laura Bergmann
Publikováno v:
Oncotarget
The albumin D-box binding protein (DBP) is a member of the PAR bZip (proline and acidic amino acid-rich basic leucine zipper) transcription factor family and functions as important regulator of circadian core and output gene expression. Gene expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5639d854f45001058f7bb25aa2496d74
https://pubmed.ncbi.nlm.nih.gov/30100984
https://pubmed.ncbi.nlm.nih.gov/30100984
Publikováno v:
Journal of Biological Rhythms. 29:87-96
The mammalian circadian clock comprises a system of interconnected transcriptional and translational feedback loops. Proper oscillator function requires the precisely timed synthesis and degradation of core clock proteins. Heat shock protein 90 (HSP9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1db03a400d8f3a224ee9d6b95e307945
https://doi.org/10.1177/0748730414523559
https://doi.org/10.1177/0748730414523559
Publikováno v:
Journal of biological rhythms. 31(2)
Our understanding of the molecular underpinnings of the mammalian circadian oscillator and its tight connection to physiology has progressed tremendously during the past decades. The liver is considered the prototypic experimental model tissue for ci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8051f40628e2bdea3c32b663b2c1a31c
https://pubmed.ncbi.nlm.nih.gov/26911716
https://pubmed.ncbi.nlm.nih.gov/26911716
Autor:
Camille Saini, Ivor J. Benjamin, Ueli Schibler, Fabienne Fleury-Olela, Hans Reinke, Charna Dibner
Publikováno v:
Genes & Development. 22:331-345
The circadian clock enables the anticipation of daily recurring environmental changes by presetting an organism’s physiology and behavior. Driven and synchronized by a central pacemaker in the brain, circadian output genes fine-tune a wide variety
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c57ccc1fa197113d0e0e5d414ba24ef1
https://doi.org/10.1101/gad.453808
https://doi.org/10.1101/gad.453808
Autor:
Hans Reinke, Gad Asher
Publikováno v:
Gastroenterology. 150(3)
The circadian clock is an endogenous biological timekeeping system that synchronizes physiology and behavior to day/night cycles. A wide variety of processes throughout the entire gastrointestinal tract and notably the liver appear to be under circad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63a4754fcc6e4bb2e20cf71735f5f6b9
https://pubmed.ncbi.nlm.nih.gov/26657326
https://pubmed.ncbi.nlm.nih.gov/26657326