Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Hans, Kretzschmar"'
Autor:
Sabina Eigenbrod, Petra Frick, Uwe Bertsch, Gerda Mitteregger-Kretzschmar, Janina Mielke, Marko Maringer, Niklas Piening, Alexander Hepp, Nathalie Daude, Otto Windl, Johannes Levin, Armin Giese, Vignesh Sakthivelu, Jörg Tatzelt, Hans Kretzschmar, David Westaway
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188989 (2017)
Prion diseases have been linked to impaired copper homeostasis and copper induced-oxidative damage to the brain. Divalent metal ions, such as Cu2+ and Zn2+, bind to cellular prion protein (PrPC) at octapeptide repeat (OR) and non-OR sites within the
Externí odkaz:
https://doaj.org/article/768e6387c51240a48de92b6362f601c9
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 2, Pp 233-241 (2009)
Both the cellular prion protein (PrPc) and the amyloid precursor protein (APP) are physiologically subjected to complex proteolytic processing events. While for APP the proteinases involved – alpha-, beta- and gamma-secretase – have been identifi
Externí odkaz:
https://doaj.org/article/82a88bb342b845d6b0bbecae11ff7e5a
Autor:
Sabina Eigenbrod, Niklas Thon, Nathalie Jansen, Hendrik Janssen, Janina Mielke, Michael Ruiter, Christian la Fougère, Aurelia Peraud, Rupert Egensperger, Hans Kretzschmar
Publikováno v:
Rare Tumors, Vol 4, Iss 2, Pp e30-e30 (2012)
Intramedullary glioma are rare and their biological behaviour can differ from their cerebral counterparts. Pilomyxoid astrocytoma (PMA, WHO grade II), predominantly occur in the hypothalamic/chiasmatic region of infants and children. The few reported
Externí odkaz:
https://doaj.org/article/ced129ffcdc5483090394d46357efb9f
Autor:
Oliver Schnell, Alexander Romagna, Irene Jaehnert, Valerie Albrecht, Sabina Eigenbrod, Kathrin Juerchott, Hans Kretzschmar, Jörg-Christian Tonn, Christian Schichor
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e30429 (2012)
Krüppel-like factor 8 (KLF8) has only recently been identified to be involved in tumor cell proliferation and invasion of several different tumor entities like renal cell carcinoma, hepatocellular carcinoma and breast cancer. In the present study, w
Externí odkaz:
https://doaj.org/article/9dff591685cf4358bff3125f8aab0570
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42545 (2012)
Synucleinopathies such as Parkinson's disease, multiple system atrophy and dementia with Lewy bodies are characterized by deposition of aggregated α-synuclein. Recent findings indicate that pathological oligomers rather than fibrillar aggregates may
Externí odkaz:
https://doaj.org/article/3705dc3c515e4ef1ac514517918fae64
Autor:
Tobias Bittner, Martin Fuhrmann, Steffen Burgold, Simon M Ochs, Nadine Hoffmann, Gerda Mitteregger, Hans Kretzschmar, Frank M LaFerla, Jochen Herms
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15477 (2010)
The pathology of Alzheimer's disease (AD) is characterized by the accumulation of amyloid-β (Aβ) peptide, hyperphosphorylated tau protein, neuronal death, and synaptic loss. By means of long-term two-photon in vivo imaging and confocal imaging, we
Externí odkaz:
https://doaj.org/article/f731e9ad8c4e4746b373ee99dd2ebbae
Autor:
Bogdana, Suchorska, Nathalie L, Jansen, Jennifer, Linn, Hans, Kretzschmar, Hendrik, Janssen, Sabina, Eigenbrod, Matthias, Simon, Gabriele, Pöpperl, Friedrich W, Kreth, Christian, la Fougere, Michael, Weller, Joerg C, Tonn, Bettina, Henschel
Objective: The aim of this prospective longitudinal study was to identify static and dynamic O -(2-[ 18 F]fluoroethyl)-l-tyrosine PET ( 18 FET-PET)-derived imaging biomarkers in patients with glioblastoma (GBM). Methods: Seventy-nine patients with ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2744068028803f6d2f5dc2f93ffcbba
https://www.zora.uzh.ch/id/eprint/106794/
https://www.zora.uzh.ch/id/eprint/106794/
Autor:
Niklas, Thon, Mathias, Kunz, Lena, Lemke, Nathalie L, Jansen, Sabina, Eigenbrod, Simone, Kreth, Jürgen, Lutz, Rupert, Egensperger, Armin, Giese, Jochen, Herms, Michael, Weller, Hans, Kretzschmar, Jörg-Christian, Tonn, Christian, la Fougère, Friedrich-Wilhelm, Kreth
Publikováno v:
International journal of cancer. 136(9)
In suspected grade II gliomas, three distinct patterns of time-activity curves (TAC) on O-(2-[(18)F]fluoroethyl)-1-tyrosine ((18)F-FET) positron emission tomography (PET) have been delineated (i) increasing TAC homogeneously throughout the tumor, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3bdf5684011d0008f1aaf6fe46cea1d2
https://pubmed.ncbi.nlm.nih.gov/25311315
https://pubmed.ncbi.nlm.nih.gov/25311315
Autor:
Walter, Rachinger, Sabina, Eigenbrod, Stephan, Dützmann, Matthias, Simon, Guenther C, Feigl, Natalia, Kremenevskaja, Hans, Kretzschmar, Stefan, Zausinger, Friedrich-Wilhelm, Kreth, Niklas, Thon, Jörg-Christian, Tonn
Publikováno v:
Journal of neurosurgery. 120(6)
Chordomas of the skull base are rare and locally invasive and have a poor prognosis. The aim of this retrospective multicenter study was to evaluate the current pattern of care and clinical course and to identify prognostic factors.A total of 47 pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f077423e4575a538cdb5cabd2e6535f8
https://pubmed.ncbi.nlm.nih.gov/24405075
https://pubmed.ncbi.nlm.nih.gov/24405075