Förster Resonance Energy Transfer Based Biosensor for Targeting the hNTH1–YB1 Interface as a Potential Anticancer Drug Target

Autor: Senarisoy, Muge, Barette, Caroline, Lacroix, Françoise, Debonis, Salvatore, Stelter, Meike, Hans, Fabienne, Kleman, Jean-Philippe, Fauvarque, Marie-Odile, Timmins, Joanna

Publikováno v: ACS Chemical Biology
ACS Chemical Biology, American Chemical Society, 2020, 15 (4), pp.990-1003. ⟨10.1021/acschembio.9b01023⟩
ACS Chemical Biology, 2020, 15 (4), pp.990-1003. ⟨10.1021/acschembio.9b01023⟩

International audience; The Y-box binding protein 1 (YB1) is an established metastatic marker: high expression and nuclear localization of YB1 correlate with tumor aggressiveness, drug resistance and poor patient survival in various tumors. In the nu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::90b381889b4f841827f5227c0a47f5dd
https://hal-cea.archives-ouvertes.fr/cea-02517754/file/Preprint_Senarisoy_etal.pdf

Characterizing Intact Macromolecular Complexes Using Native Mass Spectrometry

Autor: Boeri Erba, Elisabetta, Signor, Luca, Oliva, Mizar Francesca, Hans, Fabienne, Petosa, Carlo

Publikováno v: Methods in molecular biology (Clifton, N.J.)
Methods in molecular biology (Clifton, N.J.), 2018, 1764, pp.133-151. 〈10.1007/978-1-4939-7759-8_9〉
Methods in Molecular Biology
Methods in Molecular Biology, 2018, 1764, pp.133-151. ⟨10.1007/978-1-4939-7759-8_9⟩
Methods in Molecular Biology, Humana Press/Springer Imprint, 2018, 1764, pp.133-151. ⟨10.1007/978-1-4939-7759-8_9⟩

International audience; Native mass spectrometry (MS) enables the characterization of macromolecular assemblies with high sensitivity. It can reveal the stoichiometry of subunits as well as their two-dimensional interaction network and provide inform

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b8c354e2ed9431bf2bca4bdc245ad821
https://hal.archives-ouvertes.fr/hal-01807803

Mutagenesis of Amino Acids at Two Tomato Ringspot Nepovirus Cleavage Sites: Effect on Proteolytic Processingin cisandin transby the 3C-like Protease

Autor: Carrier, Karma, Hans, Fabienne, Sanfaçon, Hélène

Publikováno v: In Virology 25 May 1999 258(1):161-175

Aurora A transformation to Aurora B

Autor: Hans, Fabienne, Skoufias, Dimitrios, Dimitrov, Stefan, Margolis, Robert

Publikováno v: Molecular Biology of the Cell
Molecular Biology of the Cell, American Society for Cell Biology, 2009, 20 (15), pp.3491-502. ⟨10.1091/mbc.E09-05-0370⟩
Molecular Biology of the Cell, 2009, 20 (15), pp.3491-502. ⟨10.1091/mbc.E09-05-0370⟩

International audience; Aurora A and Aurora B, paralogue mitotic kinases, share highly similar primary sequence. Both are important to mitotic progression, but their localizations and functions are distinct. We have combined shRNA suppression with ov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0fa618b1f7c2efb961226e385be7cd24
https://www.hal.inserm.fr/inserm-00445539/document

Localization of aurora A and aurora B kinases during interphase: role of the N-terminal domain.: Interphase localization of Aurora kinases A and B

Autor: Rannou, Yoann, Troadec, Marie-Bérengère, Petretti, Clotilde, Hans, Fabienne, Dutertre, Stéphanie, Dimitrov, Stefan, Prigent, Claude

Publikováno v: Cell Cycle
Cell Cycle, Taylor & Francis, 2008, 7 (19), pp.3012-20. ⟨10.4161/cc.7.19.6718⟩
Cell Cycle, 2008, 7 (19), pp.3012-20. ⟨10.4161/cc.7.19.6718⟩

International audience; Aurora kinases possess a conserved catalytic domain (CD) and a N-terminal domain (ND) that varies in size and sequence. We have previously reported that the N-terminal domain of AuroraA (AurA) participates in the localization

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::d90119002acb3d82c7968e0d91f87015
https://www.hal.inserm.fr/inserm-00319921