Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Hanoch Senderowitz"'
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 23, Iss , Pp 1244-1259 (2024)
Understanding protein-protein interactions (PPIs) at the molecular level may lead to innovations in medicine and biochemistry. The assumption that there are certain “hot spots” on protein surfaces that mediate their interactions with other protei
Externí odkaz:
https://doaj.org/article/4ef4296776284edab83042250479b31f
Autor:
Majdi Saleem Naamneh, Tatjana Momic, Michal Klazas, Julius Grosche, Johannes A. Eble, Cezary Marcinkiewicz, Netaly Khazanov, Hanoch Senderowitz, Amnon Hoffman, Chaim Gilon, Jehoshua Katzhendler, Philip Lazarovici
Publikováno v:
Pharmaceuticals, Vol 17, Iss 5, p 549 (2024)
To develop peptide drugs targeting integrin receptors, synthetic peptide ligands endowed with well-defined selective binding motifs are necessary. The snake venom KTS-containing disintegrins, which selectively block collagen α1β1 integrin, were use
Externí odkaz:
https://doaj.org/article/a2507c50643f46cfb8943819957681cd
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
IntroductionThe eons-long co-evolvement of plants and bacteria led to a plethora of interactions between the two kingdoms, in which bacterial pathogenicity is counteracted by plant-derived antimicrobial defense molecules. In return, efflux pumps (EP)
Externí odkaz:
https://doaj.org/article/cb0b2891bd784b9ab7e2397bf75eb929
Autor:
Hadar Binyamin, Hanoch Senderowitz
Publikováno v:
npj Computational Materials, Vol 8, Iss 1, Pp 1-17 (2022)
Abstract Dye-sensitized solar cells (DSSCs) are cost-effective, sustainable, and versatile electricity producers, allowing them to be incorporated into a variety of devices. In this work, we explore the usage of pharmacophore modeling to identify met
Externí odkaz:
https://doaj.org/article/1f8a236d89a7489cb41dadbe152b6461
Autor:
Uthman Okalang, Bar Mualem Bar-Ner, K. Shanmugha Rajan, Nehemya Friedman, Saurav Aryal, Katarina Egarmina, Ronen Hope, Netaly Khazanov, Hanoch Senderowitz, Assaf Alon, Deborah Fass, Shulamit Michaeli
Publikováno v:
mBio, Vol 12, Iss 6 (2021)
ABSTRACT In the parasite Trypanosoma brucei, the causative agent of human African sleeping sickness, all mRNAs are trans-spliced to generate a common 5′ exon derived from the spliced leader (SL) RNA. Perturbations of protein translocation across th
Externí odkaz:
https://doaj.org/article/c006c5e1a7c34feda5e9288d961cce36
Autor:
Manoj Pun, Netaly Khazanov, Ortal Galsurker, Michal Weitman, Zohar Kerem, Hanoch Senderowitz, Iris Yedidia
Publikováno v:
Frontiers in Plant Science, Vol 12 (2021)
The effects of phloretin a phytoalexin from apple, was tested on Pectobacterium brasiliense (Pb1692), an emerging soft-rot pathogen of potato. Exposure of Pb1692 to 0.2 mM phloretin a concentration that does not affect growth, or to 0.4 mM a 50% grow
Externí odkaz:
https://doaj.org/article/1c24325e583c4e468a78a877b0ac5cce
Autor:
Omer Kaspi, Osnat Israelsohn-Azulay, Zidon Yigal, Hila Rosengarten, Matea Krmpotić, Sabrina Gouasmia, Iva Bogdanović Radović, Pasi Jalkanen, Anna Liski, Kenichiro Mizohata, Jyrki Räisänen, Zsolt Kasztovszky, Ildikó Harsányi, Raghunath Acharya, Pradeep K. Pujari, Molnár Mihály, Mihaly Braun, Nahum Shabi, Olga Girshevitz, Hanoch Senderowitz
Publikováno v:
Journal of Chemical Information and Modeling. 63:87-100
Glass fragments found in crime scenes may constitute important forensic evidence when properly analyzed, for example, to determine their origin. This analysis could be greatly helped by having a large and diverse database of glass fragments and by us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c9cdbc2dd7166a11fd3c2ca27e7d675
https://doi.org/10.1021/acs.jcim.2c01362
https://doi.org/10.1021/acs.jcim.2c01362
Publikováno v:
Journal of Cheminformatics, Vol 9, Iss 1, Pp 1-15 (2017)
Abstract An important aspect of chemoinformatics and material-informatics is the usage of machine learning algorithms to build Quantitative Structure Activity Relationship (QSAR) models. The RANdom SAmple Consensus (RANSAC) algorithm is a predictive
Externí odkaz:
https://doaj.org/article/61e154fc91284dcd94accda3886feda8
Autor:
Malkeet Singh Bahia, Omer Kaspi, Meir Touitou, Idan Binayev, Seema Dhail, Jacob Spiegel, Netaly Khazanov, Abraham Yosipof, Hanoch Senderowitz
Publikováno v:
Molecular Informatics. 42
QSAR models are widely and successfully used in many research areas. The success of such models highly depends on molecular descriptors typically classified as 1D, 2D, 3D, or 4D. While 3D information is likely important, e.g., for modeling ligand-pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5472aa9f935f5b23f0991f556ca1dbf9
https://doi.org/10.1002/minf.202200186
https://doi.org/10.1002/minf.202200186
Autor:
Andrea Atzmon, Melisa Herrero, Reut Sharet-Eshed, Yocheved Gilad, Hanoch Senderowitz, Orna Elroy-Stein
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
Vanishing white matter (VWM) disease is an autosomal genetic leukodystrophy caused by mutations in subunits of eukaryotic translation initiation factor 2B (eIF2B). The clinical symptoms exhibit progressive loss of white matter in both hemispheres of
Externí odkaz:
https://doaj.org/article/26ae6a290dec4bf4be2006542cef2dce