Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Hanny Musa"'
Autor:
Ulrike Tontsch-Grunt, Paula-Elena Traexler, Anke Baum, Hanny Musa, Kristell Marzin, Shaonan Wang, Francesca Trapani, Harald Engelhardt, Flavio Solca
Publikováno v:
British journal of cancer. 127(3)
Background BET inhibitors have been tested in several clinical trials where, despite encouraging preclinical results, substantial clinical benefit in monotherapy remains limited. This work illustrates the translational challenges and reports new data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff07294034092aed37a32806a8fac2f
https://pubmed.ncbi.nlm.nih.gov/35444289
https://pubmed.ncbi.nlm.nih.gov/35444289
Autor:
Sonja Loges, Juergen Braunger, Hanny Musa, Ralph Graeser, Linda Scarrott, Klaus Pantel, Harriet Wikman
Publikováno v:
Cancer Research. 78:3610-3610
The IMI-funded CANCER-ID consortium (https://www.cancer-id.eu/) was created in order to facilitate the use of Circulating Tumor Cells (CTCs) and other liquid biopsies (ctDNA, miRNA, exosomes) in the monitoring and treatment of cancer, via establishin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5e0d779123c875a4daf658bd7ab95a5
https://doi.org/10.1158/1538-7445.am2018-3610
https://doi.org/10.1158/1538-7445.am2018-3610
Autor:
Peter C. M. Molenaar, James O. Tellez, Vinod Sharma, Robert H. Anderson, N.J. Chandler, Shin Inada, Mark R. Boyett, Mirko Baruscotti, Daniel C. Sigg, Hanny Musa, Halina Dobrzynski, Renato Longhi, I.D. Greener, Rudolf Billeter, Dario DiFrancesco
Publikováno v:
Circulation. 119:1562-1575
Background— Although we know much about the molecular makeup of the sinus node (SN) in small mammals, little is known about it in humans. The aims of the present study were to investigate the expression of ion channels in the human SN and to use th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ffa70fe1c79cbf6ebd6073f24c0003e
https://doi.org/10.1161/circulationaha.108.804369
https://doi.org/10.1161/circulationaha.108.804369
Publikováno v:
Journal of Cell Science. 116:4811-4819
Titin is the largest protein known, and is essential for organising muscle sarcomeres. It has many domains with a variety of functions, and stretches from the Z-line to the M-line in the muscle sarcomere. Close to the M-line, titin contains a kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b7c26fda7997ff3c6c59bc3ae33b1aa
https://doi.org/10.1242/jcs.00768
https://doi.org/10.1242/jcs.00768
Publikováno v:
Journal of Muscle Research and Cell Motility. 24:303-310
When myoblasts fuse into myotubes, the organisation of the cytoskeleton changes dramatically. For example, microtubules emanate in a radial array form the centrosome in myoblasts, but form linear arrays not linked to a centrosome in myotubes. It is n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ecd4dfdde48e1cb94b7c83bb2bea878
https://doi.org/10.1023/a:1025477807393
https://doi.org/10.1023/a:1025477807393
Autor:
Herlinde Dumez, Chooi Lee, Philippe Aftimos, Patrick Schöffski, Ute Burkard, Ahmad Awada, Jo Costermans, Yihua Zhao, Marie-Anne Meeus, Christiane Jungels, Nathalie Huyvaert, Hanny Musa, Oliver Bechter
Publikováno v:
Journal of Clinical Oncology. 35:2504-2504
2504 Background: The BET family (BRD2, BRD3, BRD4) regulates transcription, epigenetic memory and cell growth, emerging as a novel therapeutic strategy. BI 894999 is a highly potent and selective orally available BET inhibitor. Methods: BI 894999 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::52c6449d484e9a33fceed4d3423ca5b5
https://doi.org/10.1200/jco.2017.35.15_suppl.2504
https://doi.org/10.1200/jco.2017.35.15_suppl.2504
Autor:
Zaineb Henderson, Mark R. Boyett, Haruo Honjo, David Marples, Hanny Musa, Yoshiko Takagishi, Halina Dobrzynski, Itsuo Kodama, Tomoko T. Yamanushi
Publikováno v:
Journal of Histochemistry & Cytochemistry. 49:1221-1234
The functionally important effects on the heart of ACh released from vagal nerves are principally mediated by the muscarinic K+ channel. The aim of this study was to determine the abundance and cellular location of the muscarinic K+ channel subunits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9906f454a436e294a3c0c0c2fdc004c8
https://doi.org/10.1177/002215540104901004
https://doi.org/10.1177/002215540104901004
Autor:
Lucy Atkinson, Carol J. Milligan, Trevor F.C. Batten, Simon H. Parson, Hanny Musa, Susan A. Deuchars, Jim Deuchars, Noel J. Buckley, Ruth E. Brooke
Publikováno v:
Europe PubMed Central
The ionotropic ATP receptor subunits P2X(1-6) receptors play important roles in synaptic transmission, yet the P2X(7) receptor has been reported as absent from neurons in the normal adult brain. Here we use RT-PCR to demonstrate that transcripts for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4722616e473dcc3a6998e480d14b82e8
https://doi.org/10.1523/jneurosci.21-18-07143.2001
https://doi.org/10.1523/jneurosci.21-18-07143.2001
Autor:
Fabio Savarese, Anke Baum, Norbert Kraut, Daniel Gerlach, Norbert Schweifer, Dirk Scharn, Chooi Lee, Marco H. Hofmann, Harald Engelhardt, Hanny Musa, Gerd Munzert, Johannes Popow, Ulrike Tontsch-Grunt
Publikováno v:
European Journal of Cancer. 69:S89
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d7e291cff2f368fd43fbaca50f107f2
https://doi.org/10.1016/s0959-8049(16)32862-3
https://doi.org/10.1016/s0959-8049(16)32862-3
Autor:
Harald Engelhardt, Marco H. Hofmann, Dirk Scharn, Anke Baum, Fabio Savarese, Gerd Munzert, Norbert Kraut, Hanny Musa, Daniel Gerlach, Norbert Schweifer, Ulrike Tontsch-Grunt, Chooi Lee, Onur Kaya
Publikováno v:
Journal of Clinical Oncology. 34:11574-11574
11574Background: BRD4 is a key epigenetic regulator facilitating transcriptional elongation of super-enhancer regulated oncogenes including MYC. BI 894999, a novel, potent and selective orally bioa...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28dcba81fe99e65d63072ceccebc8cc9
https://doi.org/10.1200/jco.2016.34.15_suppl.11574
https://doi.org/10.1200/jco.2016.34.15_suppl.11574