Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Hanny Klaasse Bos"'
Autor:
Jelle de Wit, Yuri Souwer, Tineke Jorritsma, Hanny Klaasse Bos, Anja ten Brinke, Jacques Neefjes, S Marieke van Ham
Publikováno v:
PLoS ONE, Vol 5, Iss 9, p e13016 (2010)
BACKGROUND: The eradication of facultative intracellular bacterial pathogens, like Salmonella typhi, requires the concerted action of both the humoral immune response and the cytotoxic CD8(+) T cell response. Dendritic cells (DCs) are considered to o
Externí odkaz:
https://doaj.org/article/7d65b1d8ddc04a568ba0cefe408f28b3
Autor:
Ester B. M. Remmerswaal, M Makuch, Jacques Neefjes, Ineke J. M. ten Berge, Tineke Jorritsma, S. Marieke van Ham, Jelle de Wit, Hanny Klaasse Bos, Yuri Souwer
Publikováno v:
Journal of allergy and clinical immunology, 135(4), 1053-1060. Mosby Inc.
Background B cells mediate humoral immunity against pathogens but also direct CD4 + T-cell responses. Recent plasticity studies in mice have challenged the concept of strict fate commitment during CD4 + T-cell differentiation into distinct subsets. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0453fa8e6f523bfca597b554fc151e39
https://doi.org/10.1016/j.jaci.2014.08.012
https://doi.org/10.1016/j.jaci.2014.08.012
Autor:
Femke J. M. Muller, S. Marieke van Ham, Hanny Klaasse Bos, Astrid J. van Beelen, Yuri Souwer, Martien L. Kapsenberg, Tineke Jorritsma, Jelle de Wit, Esther C. de Jong, Rosa de Groot
Publikováno v:
Blood, 118(23), 6107-6114. American Society of Hematology
IL-17–producing CD4+ T helper (Th17) cells are important for immunity against extracellular pathogens and in autoimmune diseases. The factors that drive Th17 development in human remain a matter of debate. Here we show that, compared with classic C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::285e4c1796cce9b54c65522b5f00d77e
https://doi.org/10.1182/blood-2011-05-352682
https://doi.org/10.1182/blood-2011-05-352682
Autor:
Just P. J. Brakenhoff, Joachim Grötzinger, Stefan Rose-John, Lucien A. Aarden, Hanny Klaasse Bos
Publikováno v:
FEBS Letters. 395:235-240
We have previously shown that L58 in the putative 5th helical region of human interleukin-6 (IL-6) is important for activation of the IL-6 signal transducer gp130 [de Hon et al. (1995) FEBS Lett. 369, 187–191]. To further explore the importance of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c71a71ef559fe5871ab78aaaeb8e9d1e
https://doi.org/10.1016/0014-5793(96)00974-x
https://doi.org/10.1016/0014-5793(96)00974-x
Autor:
Stefan Rose-John, Martina Fischer, Joachim Grötzinger, Hanny Klaasse Bos, Just P. J. Brakenhoff, Marc Ehlers
Publikováno v:
Scopus-Elsevier
The pleiotropic cytokine interleukin-6 (IL-6) has been predicted to be a protein with four antiparallel alpha-helices. On target cells, IL-6 interacts with a specific ligand binding receptor subunit (IL-6R), and this complex associates with the signa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9bfc950e1e646698b26f0dd17946105
https://doi.org/10.1089/jir.1996.16.569
https://doi.org/10.1089/jir.1996.16.569
Autor:
Anja ten Brinke, Yuri Souwer, Jelle de Wit, S. Marieke van Ham, Jacques Neefjes, Hanny Klaasse Bos, Tineke Jorritsma
Publikováno v:
PLoS ONE
PLoS ONE, 5(9):e13016. Public Library of Science
PLoS ONE, 5(9). Public Library of Science
PLoS ONE, Vol 5, Iss 9, p e13016 (2010)
PLoS ONE, 5(9):e13016. Public Library of Science
PLoS ONE, 5(9). Public Library of Science
PLoS ONE, Vol 5, Iss 9, p e13016 (2010)
BACKGROUND: The eradication of facultative intracellular bacterial pathogens, like Salmonella typhi, requires the concerted action of both the humoral immune response and the cytotoxic CD8(+) T cell response. Dendritic cells (DCs) are considered to o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e10f8d09fc051c1912401779e73ca249
http://europepmc.org/articles/PMC2946406
http://europepmc.org/articles/PMC2946406
Autor:
Tineke Jorritsma, S. Marieke van Ham, Esther C. de Jong, Jelle de Wit, Yuri Souwer, Martien L. Kapsenberg, Femke J. M. Muller, Hanny Klaasse Bos
Publikováno v:
Blood, 119(20), 4812-4813. American Society of Hematology
With interest we read the letter by Ayyoub and coworkers who compare the efficacy of Th17 differentiation from naive FOXP3+CD25+CD127− NTregs and conventional naive T cells.[1][1] We previously reported that compared with CD28, alternative costimul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff713e5db52aa808378be2ac994fe240
https://doi.org/10.1182/blood-2012-03-415208
https://doi.org/10.1182/blood-2012-03-415208
Autor:
Hanny Klaasse Bos, Marc Ehlers, Stefan Rose-John, Floris D. de Hon, Axel Wollmer, Joachim Grötzinger, Hildegard Schmitz-Van de Leur, Just P. J. Brakenhoff, Ursula Horsten, Günther Kurapkat
Publikováno v:
The Journal of biological chemistry. 270(14)
The pleiotropic cytokine interleukin-6 (IL-6) interacts with the specific ligand binding subunit (IL-6R alpha) of the IL-6 receptor, and this complex associates with the signal-transducing subunit gp130 (IL-6R beta). Human IL-6 acts on human and muri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b0cbf7cab2fee97945c89bd17bdbf3
https://pubmed.ncbi.nlm.nih.gov/7713920
https://pubmed.ncbi.nlm.nih.gov/7713920
Autor:
Saskia B. Ebeling, Hanny Klaasse Bos, F D de Hon, Just P. J. Brakenhoff, Marc Ehlers, Stefan Rose-John, Lucien A. Aarden
Publikováno v:
The Journal of Experimental Medicine
The pleiotropic cytokine interleukin 6 (IL-6) plays a role in the pathogenesis of various diseases, such as multiple myeloma, autoimmune and inflammatory diseases and osteoporosis. Therefore, specific inhibitors of IL-6 may have clinical applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::418836c2177c0c78472114049c62c08a
https://pubmed.ncbi.nlm.nih.gov/7964514
https://pubmed.ncbi.nlm.nih.gov/7964514
Autor:
Hanny Klaasse Bos, Günther Kurapkat, Floris D. de Hon, Joachim Grötzinger, Stefan Rose-John, Lucien A. Aarden, Saskia B. Ebeling, Just P. J. Brakenhoff
Publikováno v:
FEBS Letters. (2-3):187-191
A model of the tertiary structure of human IL-6, derived from the crystal-structure of granulocyte-colony stimulating factor, reveals a 5th helical region in the loop between the first and second alpha-helix. To investigate the importance of this reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb97509307d408043b9fdf63ea226c4