Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Hannu Kojola"'
Publikováno v:
Analytical and Bioanalytical Chemistry. 391:2135-2144
Direct measurement of time-resolved fluorescence from a washed surface of an immunoassay well constitutes an advantage compared with label development options involving signal generation in solution. Epi-fluorometric detection collects the signal fro
Autor:
Piia von Lode, Tero Soukka, Timo Lövgren, Jussi Nurmi, Hannu Kojola, Virve Hagren, Anniina Syrjälä
Publikováno v:
Analytical Biochemistry. 374:411-416
We have developed a novel instrument platform, GenomEra, for small-scale analysis of nucleic acids. The platform combines a rapid thermal cycler, an integrated time-resolved fluorescence measurement unit, and user-friendly software for the analysis o
Publikováno v:
Microscopy Research and Technique. 28:149-154
In the present study europium chelates were introduced as alternative fluorescent labels for microscopy and their effect on enhanced autofluorescence caused by the glutaraldehyde fixative was investigated. Glutaraldehyde fixation was used to stabiliz
Autor:
Lahja Sevéus, Raimo Harju, Mikko Väisälä, Erkki Soini, Stina Syrjänen, Minna Sandberg, Hannu Kojola, Juha Salo, Ari Kuusisto, Ilkka Hemmilä
Publikováno v:
Cytometry. 13:329-338
Fluorescent lanthanide chelates with long decay times allow the suppression of the fast decaying autofluorescence in biological specimens. This property makes lanthanide chelates attractive as labels for fluorescence microscopy. As a consequence of t
Publikováno v:
Radiocarbon. 34:402-405
We have designed a 0.3-ml Teflon minivial for 14C dating of small samples in a liquid scintillation counter. We use a special adapter of standard vial size to optimize the position of the vial with respect to the phototubes and to intercept the light
Autor:
Hannu Kojola, Jussi Nurmi, Timo Lövgren, Virve Hagren, Piia von Lode, Anniina Syrjälä, Tero Soukka
Publikováno v:
Clinical chemistry. 53(11)
Nucleic acid diagnostic techniques are increasingly used for bacterial detection (1). However, because of a lack of automation, DNA testing has thus far been mainly performed by laboratory personnel with a high level of expertise in molecular biology
Publikováno v:
Journal of immunological methods. 208(2)
The prodromal period of insulin-dependent diabetes mellitus (IDDM) is characterized by circulating islet cell autoantibodies (ICA) and other beta cell specific autoantibodies. Despite biochemical characterization of the major beta cell autoantigens i
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section B: Beam Interactions with Materials and Atoms. 5:439-442
Multiparameter analog to digital conversion and multichannel pulse height analyses, enabling simultaneous acquisition of four different 1024 ch energy spectra, enhance the accuracy of low-level counting of 3H and 14C. The new LS spectrometer, the QUA
Publikováno v:
Radiocarbon. 25:577-580
A mini-gas-proportional counter prototype of 10ml capacity (at NTP) was constructed of oxygen-free Finnish copper. The counter tube will be one of 16 equivalent tubes of a small-sample gas counting system, which is equipped with passive graded shield
Publikováno v:
Radiocarbon. 26:159-165
We demonstrate the feasibility of pulse time of arrival information for early detection of periodic events in low level counting. Time of arrival data allows us to apply time series analysis and serial correlation tests which, in graphic form, give t