Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hannu Hanhijärvi"'
Publikováno v:
Pharmacologytoxicology. 75(6)
The effects of dichloromethylene bisphosphonate (clodronate) on the composition of bone mineral, morphology and histology of a long bone with an artificial femoral fracture were studied in a 22 week experiment. Two hundred twenty-four female rats wer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0e192ccacd6fcfae1b5138c63e7ce4d
https://pubmed.ncbi.nlm.nih.gov/7899261
https://pubmed.ncbi.nlm.nih.gov/7899261
Publikováno v:
Bulletin of environmental contamination and toxicology. 44(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2f616dcd32006b2bc477f931d50b23
https://pubmed.ncbi.nlm.nih.gov/2306537
https://pubmed.ncbi.nlm.nih.gov/2306537
Publikováno v:
Contact Dermatitis. 10:140-145
The skin irritant properties of a single application of dithranol (anthralin), a typical "delayed irritant", and its 10-acyl analogues in acetone or white petrolatum were compared in 3 animals models. Maximal irritation was reached at about 24 h in m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4018b9b070fac68d61d77cddecbe6461
https://doi.org/10.1111/j.1600-0536.1984.tb00019.x
https://doi.org/10.1111/j.1600-0536.1984.tb00019.x
Publikováno v:
Pharmacology & Toxicology. 61:66-68
Perfluorinated fatty acids have been used commercially as corrosion inhibitors, wetting agents, fire extinguishers and surface active agents. In an earlier study the male rats were more susceptible to the toxic effects of perfluorooctanoic acid (PFO)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::021b8e5973320dd2c13c7d5661a29324
https://doi.org/10.1111/j.1600-0773.1987.tb01775.x
https://doi.org/10.1111/j.1600-0773.1987.tb01775.x
Publikováno v:
Acta pharmacologica et toxicologica. 59(2)
Diphosphonates are compounds which prevent the crystallisation of calcium phosphates from solution. Our aim was to study the effects of clodronate (dicloromethylene diphosphonate), one of the diphosphonates, on the mineral cocentrations of dental ena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0536c4c052c8f6c1f40d2ad8b6b1c13
https://pubmed.ncbi.nlm.nih.gov/2946167
https://pubmed.ncbi.nlm.nih.gov/2946167
Autor:
Veli-Matti Kosma, Y. Collan, Pekka T. Männistö, T. Koukkari, Tapio Nevalainen, Hannu Hanhijärvi
Publikováno v:
Archives of Toxicology ISBN: 9783540165897
Indomethacin is a popular anti-inflammatory agent. One of its side-effects is gastrointestinal irritation. For the development of less irritating drug formulations it is useful to have a suitable animal model. The aim of the present study was to test
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6effe6e14a36467710c9e34e2b596aa
https://doi.org/10.1007/978-3-642-71248-7_38
https://doi.org/10.1007/978-3-642-71248-7_38
Publikováno v:
Archives of environmental contamination and toxicology. 14(6)
A method is presented for the quantitative determination of perfluorooctanoic acid in plasma and urine. The acid was esterified by an extractive alkylation method using tetrabutylammonium ion as the counter ion and benzyl bromide as the alkylating ag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0867943da4ffe79f4997d8780aa8de98
https://pubmed.ncbi.nlm.nih.gov/4073944
https://pubmed.ncbi.nlm.nih.gov/4073944
Publikováno v:
Pharmacologytoxicology. 65(4)
The urinary excretion of perfluorooctanoic acid (PFOA) was studied in male Wistar rats after castration and oestradiol administration as well as in intact females and males. During the first 24 hr females excreted 72 +/- 5% (N = 6) of a single intrap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98e325bea4ea592e6233544c376a75ca
https://pubmed.ncbi.nlm.nih.gov/2587510
https://pubmed.ncbi.nlm.nih.gov/2587510
Publikováno v:
Contact dermatitis. 15(1)
Continuous topical administration of dithranol and butantrone for 6 months caused different irritation profiles in miniature swine. In paraffin wax sticks in white petrolatum, butantrone gave rise to much less initial irritation than dithranol, but a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18dfe3ec5c16db962da10c91db46dfe1
https://pubmed.ncbi.nlm.nih.gov/2944694
https://pubmed.ncbi.nlm.nih.gov/2944694
Publikováno v:
Archives of Toxicology ISBN: 9783540136705
Anthralins, especially dithranol, have been used for the treatment of chronic dermatoses for many years. Unfortunately dithranol stains the skin yellow or brown. It also irritates healthy skin more than psoriatic areas. A new anthralin derivative, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::572d3bd162a29c203f4cd3a03f20a84d
https://doi.org/10.1007/978-3-642-69928-3_107
https://doi.org/10.1007/978-3-642-69928-3_107