Zobrazeno 1 - 10
of 325
pro vyhledávání: '"Hanns-Martin Lorenz"'
Autor:
Panagiota Xanthouli, Paul Uesbeck, Hanns-Martin Lorenz, Norbert Blank, Christina A. Eichstaedt, Satenik Harutyunova, Benjamin Egenlauf, Jerry G. Coghlan, Christopher P. Denton, Ekkehard Grünig, Nicola Benjamin
Publikováno v:
Arthritis Research & Therapy, Vol 26, Iss 1, Pp 1-10 (2024)
Abstract Background In the EDITA trial, patients with systemic sclerosis (SSc) and mild pulmonary vascular disease (PVD) treated with ambrisentan had a significant decline of pulmonary vascular resistance (PVR) but not of mean pulmonary arterial pres
Externí odkaz:
https://doaj.org/article/2e2c26b4390045a1b2e87baf0744e937
Publikováno v:
RMD Open, Vol 10, Iss 3 (2024)
Objective Previous technical limitations prevented the proof of Fcγ-receptor (FcγR)-activation by soluble immune complexes (sICs) in patients. FcγRIIIa (CD16) is a risk factor in rheumatoid arthritis (RA). We aimed at determining the presence of C
Externí odkaz:
https://doaj.org/article/f3ae4914a3f044ad8338a9dd3d730f5e
Autor:
Inga Viktoria Hensel, Szabolcs Éliás, Michelle Steinhauer, Bilgenaz Stoll, Salvatore Benfatto, Wolfgang Merkt, Stefan Krienke, Hanns-Martin Lorenz, Jürgen Haas, Brigitte Wildemann, Martin Resnik-Docampo
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 3, Pp 547-574 (2024)
Abstract Human intestinal epithelial cells are the interface between luminal content and basally residing immune cells. They form a tight monolayer that constantly secretes mucus creating a multilayered protective barrier. Alterations in this barrier
Externí odkaz:
https://doaj.org/article/b7aabe92d90649c6adf10c4fefcf4995
Autor:
Daniela Choukair, Christian Patry, Ronny Lehmann, Dorothea Treiber, Georg F. Hoffmann, Corinna Grasemann, Normi Bruck, Reinhard Berner, Peter Burgard, Hanns-Martin Lorenz, Burkhard Tönshoff
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 22, Iss 1, Pp 1-10 (2024)
Abstract Background A structured transition of adolescents and young adults with chronic autoinflammatory and autoimmune disorders from the pediatric to the adult health care system is important. To date, data on the time, processes, outcome, resourc
Externí odkaz:
https://doaj.org/article/e060731c79c141da8b3141310fccb4e5
Autor:
Nicolaj S. Hackert, Felix A. Radtke, Tarik Exner, Hanns-Martin Lorenz, Carsten Müller-Tidow, Peter A. Nigrovic, Guido Wabnitz, Ricardo Grieshaber-Bouyer
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Neutrophils are frequently studied in mouse models, but the extent to which findings translate to humans remains poorly defined. In an integrative analysis of 11 mouse and 13 human datasets, we find a strong correlation of neutrophil gene ex
Externí odkaz:
https://doaj.org/article/58065059b946472fbbc1099bf5871d69
Autor:
Angela Zink, Hanns-Martin Lorenz, Anja Strangfeld, Andreas Krause, Yvette Meissner, Tatjana Rudi, Vera Zietemann, Christian Kneitz, Martin Schaefer
Publikováno v:
RMD Open, Vol 10, Iss 2 (2024)
Objectives To investigate the impact of disease activity and treatment with disease-modifying antirheumatic drugs (DMARDs) on all-cause mortality in patients with rheumatoid arthritis and prevalent interstitial lung disease (RA-ILD).Methods Patients
Externí odkaz:
https://doaj.org/article/c3369de0d8fa47469d356f5f4c22a5d6
Autor:
Rebecca Hasseli, Frank Hanses, Melanie Stecher, Christof Specker, Tobias Weise, Stefan Borgmann, Martina Hasselberger, Bernd Hertenstein, Martin Hower, Bimba F. Hoyer, Carolin Koll, Andreas Krause, Marie von Lilienfeld-Toal, Hanns-Martin Lorenz, Uta Merle, Susana M. Nunes de Miranda, Mathias W. Pletz, Anne C. Regierer, Jutta G. Richter, Siegbert Rieg, Christoph Roemmele, Maria M. Ruethrich, Tim Schmeiser, Hendrik Schulze-Koops, Anja Strangfeld, Maria J.G.T. Vehreschild, Florian Voit, Reinhard E. Voll, Jörg Janne Vehreschild, Ulf Müller-Ladner, Alexander Pfeil
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
ObjectivesTo investigate, whether inflammatory rheumatic diseases (IRD) inpatients are at higher risk to develop a severe course of SARS-CoV-2 infections compared to the general population, data from the German COVID-19 registry for IRD patients and
Externí odkaz:
https://doaj.org/article/826148ec9ab2440794ff1f5021a13811
Autor:
Panagiota Xanthouli, Ojan Gordjani, Nicola Benjamin, Satenik Harutyunova, Benjamin Egenlauf, Alberto M. Marra, Simon Haas, Nicklas Milde, Norbert Blank, Hanns-Martin Lorenz, Christoph Fiehn, Silvia Ulrich, Oliver Distler, Ekkehard Grünig, Christina A. Eichstaedt
Publikováno v:
Arthritis Research & Therapy, Vol 25, Iss 1, Pp 1-11 (2023)
Abstract Background Patients with systemic sclerosis (SSc) are frequently affected by iron deficiency, particularly those with pulmonary hypertension (PH). The first data indicate the prognostic importance of hypochromic red cells (% HRC) > 2% among
Externí odkaz:
https://doaj.org/article/bfabf2c64b1646229e90c883e4c2be99
Autor:
Jan Leipe, Jessica C Hassel, Hanns-Martin Lorenz, Janine Günther, Manuel Feisst, Leonore Diekmann, Petros Christopoulos, Karolina Gente, Lea Daniello, Julia Will, Victor Olsavszky, M Margarida Souto-Carneiro
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 9 (2023)
Background Rheumatic immune-related adverse events (R-irAEs) occur in 5–15% of patients receiving immune checkpoint inhibitors (ICI) and, unlike other irAEs, tend to be chronic. Herein, we investigate the factors influencing cancer and R-irAEs outc
Externí odkaz:
https://doaj.org/article/2a66029fe121462dbd06630333efd7f8
Autor:
Panagiota Xanthouli, Ojan Gordjani, Nicola Benjamin, Franziska C. Trudzinski, Benjamin Egenlauf, Satenik Harutyunova, Alberto M. Marra, Nicklas Milde, Christian Nagel, Norbert Blank, Hanns-Martin Lorenz, Ekkehard Grünig, Christina A. Eichstaedt
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract Oxygenated hemoglobin (OxyHem) in arterial blood may reflect disease severity in patients with systemic sclerosis (SSc). The aim of this study was to analyze the predictive value of OxyHem in SSc patients screened for pulmonary hypertension
Externí odkaz:
https://doaj.org/article/ca79233d5db74dda8cf780ae95332587