Zobrazeno 1 - 10
of 96
pro vyhledávání: '"Hanno Hock"'
Autor:
Joan How, Siyang Ren, Jennifer Lombardi‐Story, Meghan Bergeron, Julia Foster, Phillip C. Amrein, Andrew M. Brunner, Amir T. Fathi, Hanno Hock, Anna Khachatryan, Hiroto Kikuchi, Mei Rosa Ng, Jenna Moran, Rupa Narayan, Donna Neuberg, Aura Ramos, Tina Som, Meghan Vartanian, Yi‐Bin Chen, Dan G. Duda, Gabriela S. Hobbs
Publikováno v:
eJHaem, Vol 3, Iss 2, Pp 434-442 (2022)
Abstract We conducted a single‐center, open‐label, dose escalation, and expansion phase I trial of the antiangiogenic multikinase inhibitor regorafenib in patients with advanced myeloid neoplasms. We enrolled 16 patients with relapsed/refractory
Externí odkaz:
https://doaj.org/article/b768134a01424428b03dc52b7afb2c56
Autor:
Valentina Nardi, Nora Ku, Matthew J. Frigault, Adrian M. Dubuc, Harrison Kwei Tsai, Philip C. Amrein, Gabriela S. Hobbs, Andrew M. Brunner, Rupa Narayan, Meghan E. Burke, Julia Foster, Paola Dal Cin, Marcela V. Maus, Amir T. Fathi, Hanno Hock
Publikováno v:
Blood Advances, Vol 4, Iss 1, Pp 106-111 (2020)
Abstract: Philadelphia chromosome (Ph)–like acute lymphoblastic leukemia (ALL) is a subtype of Ph-negative ALL that molecularly resembles Ph-positive ALL. It shares the adverse prognosis of Ph-positive ALL, but lacks the BCR-ABL1 fusion oncogene. I
Externí odkaz:
https://doaj.org/article/7fc7238856444e36b2853dd5b133bf4f
Autor:
Guillermo Rodríguez-Hernández, Ana Casado-García, Marta Isidro-Hernández, Daniel Picard, Javier Raboso-Gallego, Silvia Alemán-Arteaga, Alberto Orfao, Oscar Blanco, Susana Riesco, Pablo Prieto-Matos, Francisco Javier García Criado, María Begoña García Cenador, Hanno Hock, Tariq Enver, Isidro Sanchez-Garcia, Carolina Vicente-Dueñas
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
ETV6-RUNX1 is almost exclusively associated with childhood B-cell acute lymphoblastic leukemia (B-ALL), but the consequences of ETV6-RUNX1 expression on cell lineage decisions during B-cell leukemogenesis are completely unknown. Clinically silent ETV
Externí odkaz:
https://doaj.org/article/b30e171f55164cd082c50a7a24ed634f
Autor:
Wenjie Mao, Anna C. Salzberg, Motokazu Uchigashima, Yuto Hasegawa, Hanno Hock, Masahiko Watanabe, Schahram Akbarian, Yuka Imamura Kawasawa, Kensuke Futai
Publikováno v:
Cell Reports, Vol 23, Iss 11, Pp 3209-3222 (2018)
Summary: Homeostatic synaptic downscaling reduces neuronal excitability by modulating the number of postsynaptic receptors. Histone modifications and the subsequent chromatin remodeling play critical roles in activity-dependent gene expression. Histo
Externí odkaz:
https://doaj.org/article/339ce0b4e3054186867719b3a6258c5a
Autor:
Valentina Nardi, Steven L McAfee, Paola Dal Cin, Harrison K Tsai, Philip C Amrein, Gabriela S Hobbs, Andrew M Brunner, Rupa Narayan, Julia Foster, Amir T Fathi, Hanno Hock
Publikováno v:
The Oncologist. 27:82-86
BCR-ABL1 kinase inhibitors have improved the prognosis of Philadelphia-chromosome-positive (Ph+)-acute lymphoblastic leukemia (ALL). Ph-like (or BCR-ABL1-like) ALL does not express BCR-ABL1 but commonly harbors other genomic alterations of signaling
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d6069b5329e0f6f92acd2747e07497
https://doi.org/10.1093/oncolo/oyab052
https://doi.org/10.1093/oncolo/oyab052
Autor:
Philip, Amrein, Karen, Ballen, Kristen, Stevenson, Andrew, Brunner, Gabriela, Hobbs, Hanno, Hock, Steven, McAfee, Jenna, Moran, Meghan, Bergeron, Julia, Foster, Christina, Bertoli, Kristin, McGreggor, Molly, Macrea, Meghan, Burke, Tanya, Behnam, Tina, Som, Aura, Ramos, Megan, Vartanian, Jennifer, Lombardi Story, Christine, Connolly, Traci, Blonquist, Donna, Neuberg, Amir, Fathi
Publikováno v:
Leukemia & Lymphoma. 63:1428-1435
We sought to assess the safety of adding ixazomib, an oral proteasome inhibitor, to a multi-agent treatment regimen for older adults with acute lymphoblastic leukemia (ALL). Patients 51 to 75 years of age with newly diagnosed ALL were screened. Induc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d04e1e4dcbaea28e23d903a5a5446652
https://doi.org/10.1080/10428194.2021.2018582
https://doi.org/10.1080/10428194.2021.2018582
Autor:
Faisal Alsufyani, Hamid Mattoo, Dawang Zhou, Annaiah Cariappa, Denille Van Buren, Hanno Hock, Joseph Avruch, Shiv Pillai
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
The Mst1 and 2 cytosolic serine/threonine protein kinases are the mammalian orthologs of the Drosophila Hippo protein. Mst1 has been shown previously to participate in T-cell and B-cell trafficking and the migration of lymphocytes into secondary lymp
Externí odkaz:
https://doaj.org/article/176c734b83664256a6ee66754465d269
Publikováno v:
The New England Journal of Medicine
A Man with Sore Throat, Epistaxis, and Oropharyngeal Petechiae A 21-year-old man with sickle cell trait presented with sore throat, epistaxis, and petechiae of the oropharynx. The hemoglobin level ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3440d1982204e8b19b70558d9aa4c3
https://doi.org/10.1056/nejmcpc2027096
https://doi.org/10.1056/nejmcpc2027096
Autor:
Reuben Benjamin, Charlotte Graham, Deborah Yallop, Agnieszka Jozwik, Oana C Mirci-Danicar, Giovanna Lucchini, Danielle Pinner, Nitin Jain, Hagop Kantarjian, Nicolas Boissel, Marcela V Maus, Matthew J Frigault, André Baruchel, Mohamad Mohty, Athos Gianella-Borradori, Florence Binlich, Svetlana Balandraud, Fabien Vitry, Elisabeth Thomas, Anne Philippe, Sylvain Fouliard, Sandra Dupouy, Ibtissam Marchiq, Maria Almena-Carrasco, Nicolas Ferry, Sylvain Arnould, Cyril Konto, Paul Veys, Waseem Qasim, Antonio Pagliuca, Ghulam Mufti, Piers Patten, Shireen Kassam, Stephen Devereux, Majid Kazmi, Kirsty Cuthill, Victoria Potter, Andrea Kuhnl, Victoria Metaxa, Laarni Bonganay, Orla Stewart, Rose Ellard, Lorraine Catt, Jen Lewis, Farzin Farzaneh, Jackie Chappell, Alice Mason, Vicky Chu, Alan Dunlop, Adeel Saleem, Gary Cheung, Helena Munro, Elka Giemza, Oana Ciocarlie, Jan Chu, Persis Amrolia, Kanchan Rao, Robert Chiesa, Juliana Silva, Annette Hill, Maria Finch, Lindsey Young, Harvinder Hara, Sujith Samarasinghe, Anupama Rao, Ajay Vora, Kimberley Gilmour, Christine Rivat, Clare Murphy, Gulrukh Ahsan, Rasha Said Shamsah, Jesmina James, Sarah Inglott, Gary Wright, Stuart Adams, Natalia Izotova, Marina Konopleva, William Wierda, Elias Jabbour, Partow Kebrieai, Emily Jones, Kara McGee, Marcela Maus, Matthew Frigault, Jami Brown, Vesselina Toncheva, Keagan Casey, Hanno Hock, Meaghan A McKeown, Richard Mathews, Thomas Spitzer, Emmanuel Raffoux, Etienne Lengliné, Raphael Itzykson, Florence Rabian, Jérôme Larghero, Isabelle Madelaine, Elie Azoulay, Emmanuelle Clappier, Sophie Caillat-Zucman, Martine Meunier, Karine Celli-Lebras, Marie-Thérèse Tremorin, Karima Yakouben, Françoise Mechinaud-Heloury, Audrey Grain, Aurélia Alimi, Julie Roupret, Delphine Chaillou, Hélène Cavé, Aurelie Caye-Eude, Odile Fenneteau, Elodie Lainey, Jerome Naudin, Eolia Brissot, Remy Dulery, Florent Malard, Clémence Mediavilla, Agnès Bonnin, Anne Vekhoff, Tounes Ledraa, Anne Daguenel-Nguyen
Publikováno v:
The Lancet. 396:1885-1894
Summary Background Genome-edited donor-derived allogeneic anti-CD19 chimeric antigen receptor (CAR) T cells offer a novel form of CAR-T-cell product that is available for immediate clinical use, thereby broadening access and applicability. UCART19 is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ec40a8b13cd2746d839da37388e3ee8
https://doi.org/10.1016/s0140-6736(20)32334-5
https://doi.org/10.1016/s0140-6736(20)32334-5
Autor:
Reuben Benjamin, Nitin Jain, Marcela V Maus, Nicolas Boissel, Charlotte Graham, Agnieszka Jozwik, Deborah Yallop, Marina Konopleva, Matthew J Frigault, Takanori Teshima, Koji Kato, Floriane Boucaud, Svetlana Balandraud, Athos Gianella-Borradori, Florence Binlich, Ibtissam Marchiq, Sandra Dupouy, Maria Almena-Carrasco, Matthieu Pannaux, Sylvain Fouliard, Eolia Brissot, Mohamad Mohty, Laarni Bonganay, Lorraine Catt, Jackie Chappell, Gary Cheung, Vicky Chu, Kirsty Cuthill, Steven Devereux, Alan Dunlop, Rose Ellard, Farzin Farzeneh, Najeem Folarin, Elka Giemza, Shireen Kassam, Majid Kazmi, Andrea Kuhnl, Jen Lewis, Maria Liskova, Alice Mason, Victoria Metaxa, Ghulam Mufti, Helena Munro, Antonio Pagliuca, Piers Patten, Victoria Potter, Carmel Rice, Adeel Saleem, Robin Sanderson, Orla Stewart, Elias Jabbour, Emily Jones, Hagop Kantarjian, Partow Kebriaei, Kara McGee, William Wierda, Jami Brown, Keagan Casey, Matthew Frigault, Hanno Hock, Richard Mathews, Marcela Maus, Meaghan A McKeown, Thomas Spitzer, Vesselina Toncheva, Elie Azoulay, Sophie Caillat-Zucman, Karine Celli-Lebras, Emmanuelle Clappier, Raphael Itzykson, Jérôme Larghero, Etienne Lengliné, Isabelle Madelaine, Martine Meunier, Florence Rabian, Emmanuel Raffoux, Marie-Thérèse Tremorin, Agnes Bonnin, Anne Daguenel-Nguyen, Remy Dulery, Tounes Ledraa, Florent Malard, Clemence Mediavilla, Anne Vekhoff
Publikováno v:
The Lancet. Haematology. 9(11)
The prognosis for adults with relapsed or refractory B-cell acute lymphoblastic leukaemia remains poor. UCART19, an allogeneic genome-edited anti-CD19 chimeric antigen receptor (CAR) T-cell product derived from healthy donors and available for immedi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2465405ccda5010e18dfd94d694a39d
https://pubmed.ncbi.nlm.nih.gov/36271140
https://pubmed.ncbi.nlm.nih.gov/36271140