Zobrazeno 1 - 10
of 271
pro vyhledávání: '"Hanno Steen"'
Autor:
Al Ozonoff, Naresh Doni Jayavelu, Shanshan Liu, Esther Melamed, Carly E. Milliren, Jingjing Qi, Linda N. Geng, Grace A. McComsey, Charles B. Cairns, Lindsey R. Baden, Joanna Schaenman, Albert C. Shaw, Hady Samaha, Vicki Seyfert-Margolis, Florian Krammer, Lindsey B. Rosen, Hanno Steen, Caitlin Syphurs, Ravi Dandekar, Casey P. Shannon, Rafick P. Sekaly, Lauren I. R. Ehrlich, David B. Corry, Farrah Kheradmand, Mark A. Atkinson, Scott C. Brakenridge, Nelson I. Agudelo Higuita, Jordan P. Metcalf, Catherine L. Hough, William B. Messer, Bali Pulendran, Kari C. Nadeau, Mark M. Davis, Ana Fernandez Sesma, Viviana Simon, Harm van Bakel, Seunghee Kim-Schulze, David A. Hafler, Ofer Levy, Monica Kraft, Chris Bime, Elias K. Haddad, Carolyn S. Calfee, David J. Erle, Charles R. Langelier, Walter Eckalbar, Steven E. Bosinger, IMPACC Network, Bjoern Peters, Steven H. Kleinstein, Elaine F. Reed, Alison D. Augustine, Joann Diray-Arce, Holden T. Maecker, Matthew C. Altman, Ruth R. Montgomery, Patrice M. Becker, Nadine Rouphael
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Post-acute sequelae of SARS-CoV-2 (PASC) is a significant public health concern. We describe Patient Reported Outcomes (PROs) on 590 participants prospectively assessed from hospital admission for COVID-19 through one year after discharge. M
Externí odkaz:
https://doaj.org/article/ec0ddc29cd90460ca1ec27bea2b831b8
Autor:
Ho-Joon Lee, Yujiao Zhao, Ira Fleming, Sameet Mehta, Xiaomei Wang, Brent Vander Wyk, Shannon E. Ronca, Heather Kang, Chih-Hung Chou, Benoit Fatou, Kinga K. Smolen, Ofer Levy, Clary B. Clish, Ramnik J. Xavier, Hanno Steen, David A. Hafler, J. Christopher Love, Alex K. Shalek, Leying Guan, Kristy O. Murray, Steven H. Kleinstein, Ruth R. Montgomery
Publikováno v:
iScience, Vol 26, Iss 12, Pp 108387- (2023)
Summary: Infection with West Nile virus (WNV) drives a wide range of responses, from asymptomatic to flu-like symptoms/fever or severe cases of encephalitis and death. To identify cellular and molecular signatures distinguishing WNV severity, we empl
Externí odkaz:
https://doaj.org/article/22004309d1e84b60bb1a70a582178024
Autor:
Kathrin Wenger, Arthur Viode, Christoph N. Schlaffner, Patrick van Zalm, Long Cheng, Tammy Dellovade, Xavier Langlois, Anthony Bannon, Rui Chang, Theresa R. Connors, Derek Oakley, Bernhard Renard, Juri Rappsilber, Bradley Hyman, Hanno Steen, Judith A. Steen
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-15 (2023)
Abstract Background Mouse models that overexpress human mutant Tau (P301S and P301L) are commonly used in preclinical studies of Alzheimer’s Disease (AD) and while several drugs showed therapeutic effects in these mice, they were ineffective in hum
Externí odkaz:
https://doaj.org/article/0d7d9b70fb6e432d8c9dc6d0e97c6577
Autor:
Kimino Fujimura, Amanda J. Guise, Tojo Nakayama, Christoph N. Schlaffner, Anais Meziani, Mukesh Kumar, Long Cheng, Dylan J. Vaughan, Andrew Kodani, Simon Van Haren, Kenneth Parker, Ofer Levy, Ann F. Durbin, Irene Bosch, Lee Gehrke, Hanno Steen, Ganeshwaran H. Mochida, Judith A. Steen
Publikováno v:
iScience, Vol 26, Iss 7, Pp 106909- (2023)
Summary: Characterizing perturbation of molecular pathways in congenital Zika virus (ZIKV) infection is critical for improved therapeutic approaches. Leveraging integrative systems biology, proteomics, and RNA-seq, we analyzed embryonic brain tissues
Externí odkaz:
https://doaj.org/article/51cd38694972434695fcef207fb0e48f
Autor:
Simon D. van Haren, Gabriel K. Pedersen, Azad Kumar, Tracy J. Ruckwardt, Syed Moin, Ian N. Moore, Mahnaz Minai, Mark Liu, Jensen Pak, Francesco Borriello, Simon Doss-Gollin, Elisabeth M. S. Beijnen, Saima Ahmed, Michaela Helmel, Peter Andersen, Barney S. Graham, Hanno Steen, Dennis Christensen, Ofer Levy
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Respiratory syncytial virus is a major pathogen with burden observed and associated with childhood infection. Here the authors characterise a cationic adjuvant formulation and show single immunisation results in protection in a murine neonate model o
Externí odkaz:
https://doaj.org/article/928f6a30307d40df8ee70a438b361824
Autor:
Tara K Sigdel, Patrick Boada, Maggie Kerwin, Priyanka Rashmi, David Gjertson, Maura Rossetti, Swastika Sur, Dane Munar, James Cimino, Richard Ahn, Harry Pickering, Subha Sen, Rajesh Parmar, Benoit Fatou, Hanno Steen, Joanna Schaenman, Suphamai Bunnapradist, Elaine F Reed, Minnie M Sarwal, CMV Systems Immunobiology Group
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0285870 (2023)
BackgroundCytomegalovirus (CMV) infection, either de novo or as reactivation after allotransplantation and chronic immunosuppression, is recognized to cause detrimental alloimmune effects, inclusive of higher susceptibility to graft rejection and sub
Externí odkaz:
https://doaj.org/article/fabba0c1744243fcaac9e0c6f915d69e
Autor:
Hanne Van Der Heijden, Benoit Fatou, Diana Sibai, Kacie Hoyt, Maria Taylor, Kin Cheung, Jordan Lemme, Mariesa Cay, Benjamin Goodlett, Jeffery Lo, Melissa M. Hazen, Olha Halyabar, Esra Meidan, Rudy Schreiber, Camilo Jaimes, Kirsten Ecklund, Lauren A. Henderson, Margaret H. Chang, Peter A. Nigrovic, Robert P. Sundel, Hanno Steen, Jaymin Upadhyay
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 20, Iss 1, Pp 1-10 (2022)
Highlights In the current preliminary study, serum proteins associated with pain severity were identified in JIA patients. Pain-associated proteins had functional roles predominantly in immune or inflammatory processes. Correlations of pain-associate
Externí odkaz:
https://doaj.org/article/21b59a1608ff4d0b8f510734562c6859
Autor:
Patrick Boada, Benoit Fatou, Alexia A. Belperron, Tara K. Sigdel, Kinga K. Smolen, Zainab Wurie, Ofer Levy, Shannon E. Ronca, Kristy O. Murray, Juliane M. Liberto, Priyanka Rashmi, Maggie Kerwin, Ruth R. Montgomery, Linda K. Bockenstedt, Hanno Steen, Minnie M. Sarwal
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Advancement in proteomics methods for interrogating biological samples has helped identify disease biomarkers for early diagnostics and unravel underlying molecular mechanisms of disease. Herein, we examined the serum proteomes of 23 study participan
Externí odkaz:
https://doaj.org/article/2f9560c2a25d4310b30fae2d44e980e4
Autor:
Arthur Viodé, Kinga K. Smolen, Benoit Fatou, Zainab Wurie, Patrick Van Zalm, Mandy Kader Konde, Balla Moussa Keita, Richard Amento Ablam, Eleanor N. Fish, Hanno Steen
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT Ebola virus (EBV) disease (EVD) is a highly virulent systemic disease characterized by an aggressive systemic inflammatory response and impaired vascular and coagulation systems, often leading to uncontrolled hemorrhaging and death. In this
Externí odkaz:
https://doaj.org/article/624f8327b3f4481fbb8b444be734402a
Autor:
Joann Diray-Arce, Asimenia Angelidou, Kristoffer Jarlov Jensen, Maria Giulia Conti, Rachel S. Kelly, Matthew A. Pettengill, Mark Liu, Simon D. van Haren, Scott D. McCulloch, Greg Michelloti, Olubukola Idoko, Tobias R. Kollmann, Beate Kampmann, Hanno Steen, Al Ozonoff, Jessica Lasky-Su, Christine S. Benn, Ofer Levy
Publikováno v:
Cell Reports, Vol 39, Iss 5, Pp 110772- (2022)
Summary: Vaccines have generally been developed with limited insight into their molecular impact. While systems vaccinology enables characterization of mechanisms of action, these tools have yet to be applied to infants, who are at high risk of infec
Externí odkaz:
https://doaj.org/article/d0c46f541a054652876a5e94cbd057cb