Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Hannes Schmidinger"'
Autor:
Maria Morak, Hannes Schmidinger, Peter Krempl, Gerald Rechberger, Manfred Kollroser, Ruth Birner-Gruenberger, Albin Hermetter
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 7, Pp 1281-1292 (2009)
We established a novel technique for differential activity-based gel electrophoresis (DABGE) of lipolytic enzymes from two different biological samples. For this purpose, a set of three fluorescent suicide inhibitors was developed. These probes posse
Externí odkaz:
https://doaj.org/article/f8e303aaf5104183a3fd0fa1b27e62fb
Autor:
Maria Morak, Albin Hermetter, Guenter Haemmerle, Rudolf Zechner, Gernot Riesenhuber, Manfred Kollroser, Hannes Schmidinger, Gerald N. Rechberger, Florian Kronenberg
Publikováno v:
Molecular & Cellular Proteomics. 11:1777-1789
Adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) are key enzymes involved in intracellular degradation of triacylglycerols. It was the aim of this study to elucidate how the deficiency in one of these proteins affects the residua
Glycosidase profiling with immobilised glycosidase-inhibiting iminoalditols—A proof-of-concept study
Autor:
Albin Hermetter, Chris A. Tarling, Stephen G. Withers, Andreas Steiner, Arnold E. Stütz, Tanja M. Wrodnigg, Hannes Schmidinger
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 18:1922-1925
Three typical glycosidase-inhibiting iminoalditols were attached to a polyamine surface displayed on a silicon chip. Exposure to a representative beta-glucosidase revealed selective binding events reflecting the different structural features of the i
Autor:
Gernot P. Tilz, Marco Wiltgen, Ulrike Demel, Christian Faschinger, Albin Hermetter, Hannes Schmidinger
Publikováno v:
Wiener Medizinische Wochenschrift. 157:122-129
Molecular medicine leads us towards an understanding of some diseases at the molecular level. Examples are the analysis of immune complexes and receptor – anti receptor compounds used in clinical medicine. Structural changes of some serum proteins
Autor:
Gernot Riesenhuber, Hannes Schmidinger, Heidrun Susani-Etzerodt, Robert Saf, Ruth Birner-Gruenberger, Albin Hermetter
Publikováno v:
ChemBioChem. 6:1776-1781
Lipases and esterases are responsible for carboxylester hydrolysis inside and outside cells and are useful biocatalysts for (stereo)selective modification of synthetic substrates. Here we describe novel fluorescent suicide inhibitors that differ in s
Autor:
Rainer Hahn, Franz Clementschitsch, Hannes Schmidinger, Alois Jungbauer, Waltraud Kaar, Philipp Wechner, Karl Bayer, Karin Ahrer, Gerald Striedner, Monika Cserjan-Puschmann, Bernhard Auer, Clemens Achmüller, Florian Werther
Publikováno v:
Nature methods. 4(12)
We describe a prokaryotic expression system using the autoproteolytic function of N(pro) from classical swine fever virus. Proteins or peptides expressed as N(pro) fusions are deposited as inclusion bodies. On in vitro refolding by switching from cha
Publikováno v:
Enzyme Assays: High-throughput Screening, Genetic Selection and Fingerprinting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c051cbecee7d41d0319c5efd264382c0
https://doi.org/10.1002/3527607846.ch9
https://doi.org/10.1002/3527607846.ch9
Publikováno v:
Chembiochem : a European journal of chemical biology. 7(3)
Protein and small-molecule microarrays are useful tools for high-throughput analysis of DNA-protein, protein-protein, and protein-small molecule interactions. Here we report on novel microarrays for activity screening of lipases and esterases based o
Publikováno v:
Amino acids. 30(4)
In the postgenomic era new technologies are emerging for global analysis of protein function. The introduction of active site-directed chemical probes for enzymatic activity profiling in complex mixtures, known as activity-based proteomics has greatl
Autor:
Guenter Haemmerle, Rudolf Zechner, Hannes Schmidinger, Gernot Riesenhuber, Heidrun Susani-Etzerodt, Gerald N. Rechberger, Ruth Birner-Gruenberger, Albin Hermetter, Markus Waldhuber, Robert Zimmermann, Juliane G. Strauss, Manfred Kollroser, Achim Lass
Publikováno v:
Molecularcellular proteomics : MCP. 4(11)
Hydrolysis of triacylglycerols and cholesteryl esters is a key event in energy homeostasis of animals. However, many lipolytic activities still await their molecular identification. Here we report on a novel tool for concomitant analysis of lipases i