Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Hannes Schmid"'
Autor:
Anita Schmitt, Brigitte Neuber, Michael Schmitt, Melanie Märklin, Boris Klimovich, Claudia Lengerke, Emmanuelle Moraes Ribeiro, Kathy-Ann Secker, Ana-Maria Nitulescu, Rebekka Schairer, Hildegard Keppeler, Anton Wesle, Hannes Schmid, Daniela Chmiest, Silvia Podavini, Fulya Korkmaz, Corina Schneidawind, Dominik Schneidawind
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Background Relapse and graft-versus-host disease (GVHD) are the main causes of death after allogeneic hematopoietic cell transplantation (HCT). Preclinical murine models and clinical data suggest that invariant natural killer T (iNKT) cells prevent a
Externí odkaz:
https://doaj.org/article/2907d4c839b94d97ad13f309c1992704
Autor:
Jakob Einhaus, Ann-Christin Pecher, Elisa Asteriti, Hannes Schmid, Kathy-Ann Secker, Silke Duerr-Stoerzer, Hildegard Keppeler, Reinhild Klein, Corina Schneidawind, Joerg Henes, Dominik Schneidawind
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-8 (2020)
Abstract Objective Systemic sclerosis (SSc) is a connective tissue disease with a significant morbidity and reduced survival of patients. Effective treatment and clinical control of the disease remain challenging. In particular, the development of pu
Externí odkaz:
https://doaj.org/article/27b4f8019cdc4954ac224882d2b9813f
Autor:
Ann-Christin Pecher, Felix Kettemann, Elisa Asteriti, Hannes Schmid, Silke Duerr-Stoerzer, Hildegard Keppeler, Joerg Christoph Henes, Reinhild Klein, Clemens Hinterleitner, Kathy-Ann Secker, Corina Schneidawind, Lothar Kanz, Dominik Schneidawind
Publikováno v:
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-8 (2019)
Abstract Background Systemic sclerosis (SSc) is a potentially fatal autoimmune disease that leads to extensive fibrosis of the skin and internal organs. Invariant natural killer T (iNKT) cells are potent immunoregulatory T lymphocytes being able to o
Externí odkaz:
https://doaj.org/article/53722ef4c96a400bad6afe83485331f1
Autor:
Lisa Frankenreiter, Bernd M. Gahr, Hannes Schmid, Mirjam Zimmermann, Sebastian Deichsel, Philipp Hoffmeister, Aleksandra Turkiewicz, Tilman Borggrefe, Franz Oswald, Anja C. Nagel
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
The highly conserved Notch signaling pathway controls a multitude of developmental processes including hematopoiesis. Here, we provide evidence for a novel mechanism of tissue-specific Notch regulation involving phosphorylation of CSL transcription f
Externí odkaz:
https://doaj.org/article/1dc96dd13eb84d14a5b10673ca6bc5a5
Autor:
Hannes Schmid, Emmanuelle M. Ribeiro, Kathy-Ann Secker, Silke Duerr-Stoerzer, Hildegard Keppeler, Ruoyun Dong, Timo Munz, Klaus Schulze-Osthoff, Stephan Hailfinger, Corina Schneidawind, Dominik Schneidawind
Publikováno v:
Haematologica, Vol 107, Iss 2 (2021)
Graft-versus-host disease (GvHD) is a major cause of morbidity and mortality after allogeneic hematopoietic cell transplantation. We recently showed in murine studies and in vitro human models that adoptively transferred invariant natural killer T (i
Externí odkaz:
https://doaj.org/article/a686e7eee464476fa80c786a7985aa39
Autor:
Simona Jahnke, Hannes Schmid, Kathy-Ann Secker, Jakob Einhaus, Silke Duerr-Stoerzer, Hildegard Keppeler, Irmtraud Schober-Melms, Rebecca Baur, Michael Schumm, Rupert Handgretinger, Wolfgang Bethge, Lothar Kanz, Corina Schneidawind, Dominik Schneidawind
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Allogeneic hematopoietic cell transplantation (allo-HCT) is a curative treatment option for hematologic malignancies but relapse remains the most common cause of death. Infusion of donor lymphocytes (DLIs) can induce remission and prolong survival by
Externí odkaz:
https://doaj.org/article/408572c894f945a9803769e6512d431b
Autor:
Kathy-Ann Secker, Bianca Bloechl, Hildegard Keppeler, Silke Duerr-Stoerzer, Hannes Schmid, Dominik Schneidawind, Johan Jeong, Thomas Hentrich, Julia M. Schulze-Hentrich, Corina Schneidawind
Publikováno v:
Cancers, Vol 12, Iss 5, p 1342 (2020)
Epigenetic dysregulation plays a pivotal role in mixed-lineage leukemia (MLL) pathogenesis, therefore serving as a suitable therapeutic target. S-adenosylmethionine (SAM) is the universal methyl donor in human cells and is synthesized by methionine a
Externí odkaz:
https://doaj.org/article/b69c20ebf0464d549f3a319ca614d5dc
Autor:
Hannes Schmid, Corina Schneidawind, Simona Jahnke, Felix Kettemann, Kathy-Ann Secker, Silke Duerr-Stoerzer, Hildegard Keppeler, Lothar Kanz, Paul B. Savage, Dominik Schneidawind
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Graft-versus-host disease (GVHD) is a major cause of significant morbidity and mortality after allogeneic hematopoietic cell transplantation (HCT). Invariant natural killer T (iNKT) cells are potent regulators of immune responses, protect from lethal
Externí odkaz:
https://doaj.org/article/929130fb642c41e091a44c20381df024
Autor:
Heiko Praxenthaler, Anja C Nagel, Adriana Schulz, Mirjam Zimmermann, Markus Meier, Hannes Schmid, Anette Preiss, Dieter Maier
Publikováno v:
PLoS Genetics, Vol 13, Iss 5, p e1006774 (2017)
Cell fate choices during metazoan development are driven by the highly conserved Notch signalling pathway. Notch receptor activation results in release of the Notch intracellular domain (NICD) that acts as transcriptional co-activator of the DNA-bind
Externí odkaz:
https://doaj.org/article/40ddec43b486410eadf0c3ddf0121cd4
Autor:
Klaus Schulze-Osthoff, Ruoyun Dong, Timo Munz, Silke Duerr-Stoerzer, Hannes Schmid, Hildegard Keppeler, Dominik Schneidawind, Kathy-Ann Secker, Corina Schneidawind, Stephan Hailfinger, Emmanuelle M Ribeiro
Publikováno v:
Haematologica. 107:427-436
Graft-versus-host disease (GvHD) is a major cause of morbidity and mortality after allogeneic hematopoietic cell transplantation. We recently showed in murine studies and in vitro human models that adoptively transferred invariant natural killer T (i