Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Hannes Hjartarson"'
Autor:
Wei Zhou, Ben Brumpton, Omer Kabil, Julius Gudmundsson, Gudmar Thorleifsson, Josh Weinstock, Matthew Zawistowski, Jonas B. Nielsen, Layal Chaker, Marco Medici, Alexander Teumer, Silvia Naitza, Serena Sanna, Ulla T. Schultheiss, Anne Cappola, Juha Karjalainen, Mitja Kurki, Morgan Oneka, Peter Taylor, Lars G. Fritsche, Sarah E. Graham, Brooke N. Wolford, William Overton, Humaira Rasheed, Eirin B. Haug, Maiken E. Gabrielsen, Anne Heidi Skogholt, Ida Surakka, George Davey Smith, Anita Pandit, Tanmoy Roychowdhury, Whitney E. Hornsby, Jon G. Jonasson, Leigha Senter, Sandya Liyanarachchi, Matthew D. Ringel, Li Xu, Lambertus A. Kiemeney, Huiling He, Romana T. Netea-Maier, Jose I. Mayordomo, Theo S. Plantinga, Jon Hrafnkelsson, Hannes Hjartarson, Erich M. Sturgis, Aarno Palotie, Mark Daly, Cintia E. Citterio, Peter Arvan, Chad M. Brummett, Michael Boehnke, Albert de la Chapelle, Kari Stefansson, Kristian Hveem, Cristen J. Willer, Bjørn Olav Åsvold
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. Here, the authors conduct a GWAS and suggest protective effect of higher TSH on risk of thyroid cancer and goitre.
Externí odkaz:
https://doaj.org/article/7b39ae688f264dfba9a4f0d7009abe4e
Autor:
Wei Zhou, Ben Brumpton, Omer Kabil, Julius Gudmundsson, Gudmar Thorleifsson, Josh Weinstock, Matthew Zawistowski, Jonas B. Nielsen, Layal Chaker, Marco Medici, Alexander Teumer, Silvia Naitza, Serena Sanna, Ulla T. Schultheiss, Anne Cappola, Juha Karjalainen, Mitja Kurki, Morgan Oneka, Peter Taylor, Lars G. Fritsche, Sarah E. Graham, Brooke N. Wolford, William Overton, Humaira Rasheed, Eirin B. Haug, Maiken E. Gabrielsen, Anne Heidi Skogholt, Ida Surakka, George Davey Smith, Anita Pandit, Tanmoy Roychowdhury, Whitney E. Hornsby, Jon G. Jonasson, Leigha Senter, Sandya Liyanarachchi, Matthew D. Ringel, Li Xu, Lambertus A. Kiemeney, Huiling He, Romana T. Netea-Maier, Jose I. Mayordomo, Theo S. Plantinga, Jon Hrafnkelsson, Hannes Hjartarson, Erich M. Sturgis, Aarno Palotie, Mark Daly, Cintia E. Citterio, Peter Arvan, Chad M. Brummett, Michael Boehnke, Albert de la Chapelle, Kari Stefansson, Kristian Hveem, Cristen J. Willer, Bjørn Olav Åsvold
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/e6ea7faf83de4743bbec9a3698de1992
Autor:
Julius Gudmundsson, Gudmar Thorleifsson, Jon K. Sigurdsson, Lilja Stefansdottir, Jon G. Jonasson, Sigurjon A. Gudjonsson, Daniel F. Gudbjartsson, Gisli Masson, Hrefna Johannsdottir, Gisli H. Halldorsson, Simon N. Stacey, Hannes Helgason, Patrick Sulem, Leigha Senter, Huiling He, Sandya Liyanarachchi, Matthew D. Ringel, Esperanza Aguillo, Angeles Panadero, Enrique Prats, Almudena Garcia-Castaño, Ana De Juan, Fernando Rivera, Li Xu, Lambertus A. Kiemeney, Gudmundur I. Eyjolfsson, Olof Sigurdardottir, Isleifur Olafsson, Hoskuldur Kristvinsson, Romana T. Netea-Maier, Thorvaldur Jonsson, Jose I. Mayordomo, Theo S. Plantinga, Hannes Hjartarson, Jon Hrafnkelsson, Erich M. Sturgis, Unnur Thorsteinsdottir, Thorunn Rafnar, Albert de la Chapelle, Kari Stefansson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Non-medullary thyroid cancers include papillary and follicular subtypes, and are the most common type of thyroid cancer. Here, the authors extend previous work by performing a large genome-wide association study and find five novel loci associated wi
Externí odkaz:
https://doaj.org/article/da3c50ac751644d7983915abdaf9a24e
Autor:
Romana T. Netea-Maier, Erich M. Sturgis, Huiling He, Li Xu, Sandya Liyanarachchi, Fadi Nabhan, Egil Ferkingstad, Julius Gudmundsson, Pamela Brock, Gudmar Thorleifsson, Albert de la Chapelle, Matthew D. Ringel, Folkert W. Asselbergs, Theo S. Plantinga, Kari Stefansson, Jose I. Mayordomo, Jon Hrafnkelsson, Hannes Hjartarson, Vinicius Tragante, Jon G. Jonasson, Lambertus A. Kiemeney
Publikováno v:
Proceedings of the National Academy of Sciences USA, 117, 5997-6002
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences USA, 117, 11, pp. 5997-6002
Proc Natl Acad Sci U S A
Proceedings of the National Academy of Sciences USA, 117, 11, pp. 5997-6002
Genome-wide association studies (GWASs) have identified at least 10 single-nucleotide polymorphisms (SNPs) associated with papillary thyroid cancer (PTC) risk. Most of these SNPs are common variants with small to moderate effect sizes. Here we assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18f236d631c87d36d3a06c63c71cd166
http://hdl.handle.net/2066/217670
http://hdl.handle.net/2066/217670
Autor:
Leigha Senter, Ben Michael Brumpton, Julius Gudmundsson, Anita Pandit, Peter Arvan, Sandya Liyanarachchi, Matthew D. Ringel, Juha Karjalainen, George Davey Smith, Anne Heidi Skogholt, Layal Chaker, Hannes Hjartarson, Tanmoy Roychowdhury, Albert de la Chapelle, Wei Zhou, Brooke N. Wolford, Kari Stefansson, Ulla T. Schultheiss, Cristen J. Willer, Whitney E. Hornsby, Lars G. Fritsche, Theo S. Plantinga, Sarah E. Graham, Marco Medici, Jonas B. Nielsen, Li Xu, Morgan Oneka, Jose I. Mayordomo, Kristian Hveem, Cintia Eliana Citterio, Serena Sanna, William Overton, Josh Weinstock, Eirin B. Haug, Lambertus A. Kiemeney, Gudmar Thorleifsson, Chad M. Brummett, Michael Boehnke, Mitja I. Kurki, Aarno Palotie, Omer Kabil, Mark J. Daly, Alexander Teumer, Bjørn Olav Åsvold, Peter N. Taylor, Ida Surakka, Erich M. Sturgis, Romana T. Netea-Maier, Silvia Naitza, Maiken Elvestad Gabrielsen, Huiling He, Anne R. Cappola, Jon Hrafnkelsson, Matthew Zawistowski, Humaira Rasheed, Jon G. Jonasson
Publikováno v:
Nature Communications, 11, 1
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nature Communications, 11
Nature Communications, 11(1):3981. Nature Publishing Group
Nature Communications
Zhou, W, Brumpton, B M, Kabil, O, Gudmundsson, J, Thorleifsson, G, Weinstock, J, Zawistowski, M, Nielsen, J B, Chaker, L, Medici, M, Teumer, A, Naitza, S, Sanna, S, Schultheiss, U, Cappola, A, Karjalainen, J, Kurki, M I, Oneka, M, Taylor, P, Fritsche, L G, Graham, S, Wolford, B, Overton, W, Rasheed, H, Haug, E B, Gabrielsen, M, Skogholt, A H, Surakka, I, Davey Smith, G, Pandit, A, Roychowdhury, T, Hornsby, W, Jonasson, J G, Senter, L, Liyanarachchi, S, Ringel, M, Xu, LI, Kiemeney, L A, He, H, Netea-Maier, R, Mayordomo, J I, Plantinga, T, Hrafnkelsson, J, Hjartarson, H, Sturgis, E, Palotie, A, Daly, M, Citterio, C, Arvan, P, Brummett, C M, Boehnke, M, Chapelle, A D L, Stefansson, K, Hveem, K, Willer, C J & Asvold, B O 2020, ' GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse genetic association with thyroid cancer ', Nature Communications, vol. 11, 3981 . https://doi.org/10.1038/s41467-020-17718-z
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Nature Communications, 11
Nature Communications, 11(1):3981. Nature Publishing Group
Nature Communications
Zhou, W, Brumpton, B M, Kabil, O, Gudmundsson, J, Thorleifsson, G, Weinstock, J, Zawistowski, M, Nielsen, J B, Chaker, L, Medici, M, Teumer, A, Naitza, S, Sanna, S, Schultheiss, U, Cappola, A, Karjalainen, J, Kurki, M I, Oneka, M, Taylor, P, Fritsche, L G, Graham, S, Wolford, B, Overton, W, Rasheed, H, Haug, E B, Gabrielsen, M, Skogholt, A H, Surakka, I, Davey Smith, G, Pandit, A, Roychowdhury, T, Hornsby, W, Jonasson, J G, Senter, L, Liyanarachchi, S, Ringel, M, Xu, LI, Kiemeney, L A, He, H, Netea-Maier, R, Mayordomo, J I, Plantinga, T, Hrafnkelsson, J, Hjartarson, H, Sturgis, E, Palotie, A, Daly, M, Citterio, C, Arvan, P, Brummett, C M, Boehnke, M, Chapelle, A D L, Stefansson, K, Hveem, K, Willer, C J & Asvold, B O 2020, ' GWAS of thyroid stimulating hormone highlights pleiotropic effects and inverse genetic association with thyroid cancer ', Nature Communications, vol. 11, 3981 . https://doi.org/10.1038/s41467-020-17718-z
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Publsiher's version (útgefin grein)
Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. To better understand the genetic contribution to TSH levels, we conduct a GWAS meta-analysis at 22.4 million genetic marker
Thyroid stimulating hormone (TSH) is critical for normal development and metabolism. To better understand the genetic contribution to TSH levels, we conduct a GWAS meta-analysis at 22.4 million genetic marker
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd4ac27787ed586c08cf9d3f7f956b5
https://hdl.handle.net/2066/222135
https://hdl.handle.net/2066/222135
Autor:
Thorvaldur Jonsson, Hannes Helgason, Huiling He, Isleifur Olafsson, Gudmundur I. Eyjolfsson, Unnur Thorsteinsdottir, Daniel F. Gudbjartsson, Jon G. Jonasson, Enrique Prats, Julius Gudmundsson, Lilja Stefansdottir, Hrefna Johannsdottir, Gisli Masson, Li Xu, Theo S. Plantinga, Lambertus A. Kiemeney, Thorunn Rafnar, Hoskuldur Kristvinsson, Jose I. Mayordomo, Jon Hrafnkelsson, Esperanza Aguillo, Gisli H. Halldorsson, Ana de Juan, Matthew D. Ringel, Olof Sigurdardottir, Erich M. Sturgis, Leigha Senter, Sandya Liyanarachchi, Romana T. Netea-Maier, Sigurjon A. Gudjonsson, Albert de la Chapelle, Fernando Rivera, Jon K. Sigurdsson, Gudmar Thorleifsson, Almudena García-Castaño, Simon N. Stacey, Angeles Panadero, Kari Stefansson, Patrick Sulem, Hannes Hjartarson
Publikováno v:
Nature Communications
Nature Communications, 8, 14517
Nature Communications, 8, pp. 14517
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Nature Communications, 8, 14517
Nature Communications, 8, pp. 14517
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
The great majority of thyroid cancers are of the non-medullary type. Here we report findings from a genome-wide association study of non-medullary thyroid cancer, including in total 3,001 patients and 287,550 controls from five study groups of Europe
Autor:
Simon N. Stacey, Hoskuldur Kristvinsson, Unnur S. Bjornsdottir, Jeffrey R. Gulcher, Hjordis Bjarnason, Unnur Thorsteinsdottir, Theo S. Plantinga, Gisli Masson, Isleifur Olafsson, Thorunn Rafnar, Jose I. Mayordomo, Jon Hrafnkelsson, Laufey Tryggvadottir, Hilma Holm, W. G. Li, Matthew D. Ringel, Almudena García-Castaño, Lambertus A. Kiemeney, Daniel F. Gudbjartsson, Jon G. Jonasson, Angeles Panadero, Thorvaldur Jonsson, Albert de la Chapelle, Enrique Prats, Marieke de Visser, Kristleifur Kristjansson, Richard T. Kloos, Gudmundur I. Eyjolfsson, Aslaug Jonasdottir, Augustine Kong, Julius Gudmundsson, Asgeir Sigurdsson, G. Bragi Walters, Kari Stefansson, Ana de Juan, Fernando Rivera, Esperanza Aguillo, Huiling He, Rebecca Nagy, Gudmar Thorleifsson, Hafdis T. Helgadottir, Olafur T. Magnusson, Romana T. Netea-Maier, Hannes Hjartarson, Martin den Heijer, Patrick Sulem, Hrefna Johannsdottir
Publikováno v:
Gudmundsson, J, Sulem, P, Gudbjartsson, D F, Jonasson, J G, Masson, G, He, H L, Jonasdottir, A, Sigurdsson, A, Stacey, S N, Johannsdottir, H, Helgadottir, H T, Li, W, Nagy, R, Ringel, M D, Kloos, R T, de Visser, M C H, Plantinga, T S, den Heijer, M, Aguillo, E, Panadero, A, Prats, E, Garcia-Castano, A, De Juan, A, Rivera, F, Walters, G B, Bjarnason, H, Tryggvadottir, L, Eyjolfsson, G I, Bjornsdottir, U S, Holm, H, Olafsson, I, Kristjansson, K, Kristvinsson, H, Magnusson, O T, Thorleifsson, G, Gulcher, J R, Kong, A, Kiemeney, L A L M, Jonsson, T, Hjartarson, H, Mayordomo, J I, Netea-Maier, R T, de la Chapelle, A, Hrafnkelsson, J, Thorsteinsdottir, U, Rafnar, T & Stefansson, K 2012, ' Discovery of common variants associated with low TSH levels and thyroid cancer risk ', Nature Genetics, vol. 44, no. 3, pp. 319-322 . https://doi.org/10.1038/ng.1046
Nature Genetics, 44, 3, pp. 319-22
Nature Genetics, 44(3), 319-322. Nature Publishing Group
Nature Genetics, 44, 319-22
Nature Genetics, 44, 3, pp. 319-22
Nature Genetics, 44(3), 319-322. Nature Publishing Group
Nature Genetics, 44, 319-22
Contains fulltext : 110933.pdf (Publisher’s version ) (Closed access) To search for sequence variants conferring risk of nonmedullary thyroid cancer, we focused our analysis on 22 SNPs with a P < 5 x 10(-8) in a genome-wide association study on lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45686e3538b1d3986d4947cd768cc714
https://research.vumc.nl/en/publications/4d121b87-ba30-4e38-9eda-b1848e70b274
https://research.vumc.nl/en/publications/4d121b87-ba30-4e38-9eda-b1848e70b274
Publikováno v:
Laeknabladid. 95(10)
Head and neck squamous cell carcinoma (HNSCC) is relatively common and is strongly related to smoking and alcohol consumption but infection by human papillomavirus has also emerged as a risk factor for HNSCC. The treatment of these tumors is complica
Autor:
Björn Magnússon, Sigurdur Juliusson, Kjell Brøndbo, Unnur S. Bjornsdottir, Kristjan Gudmundsson, Hannes Hjartarson
Publikováno v:
Annals of allergy, asthmaimmunology : official publication of the American College of Allergy, Asthma,Immunology. 85(5)
Background Patients with exercise-induced laryngochalasia present with dyspnea and stridor during exercise. Symptoms are due to a subtotal occlusion of the larynx resulting from mucosal edema from the aryepiglottic folds being drawn into the endolary