In vivo cytokine responses to interleukin-2 immunotherapy after autologous stem cell transplantation in children with solid tumors

Autor: Dieter Körholz, J Verheyen, Hannen M, U Banning, Yong-Mi Kim, Halvard Bonig, Hans-Jürgen Laws, Wenzel Nürnberger, Wundes A

Publikováno v: Bone Marrow Transplantation. 26:91-96

The potent immunostimulatory cytokine interleukin-2 (IL-2) has been extensively investigated for its potential to induce anti-tumor immunity in a number of tumor models. Only recently the complex interplay of mutually suppressive or supportive cytoki

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d0b652c660db13a246c839a06d72b7c
https://doi.org/10.1038/sj.bmt.1702431

Cytokine-Mediated Regulation of Granulocyte Colony-Stimulating Factor Production

Autor: Halvard Bonig, Lorenz I, D.-I. Shin, U Banning, Seeger K, Yong-Mi Kim, Hannen M, Dieter Körholz

Publikováno v: Scandinavian Journal of Immunology. 50:461-468

Granulocyte colony-stimulating factor (G-CSF) is an important regulator of granulopoiesis and an inducer of T helper 2 (Th2)-related cytokines. In this study we investigated the mechanism of cytokine-modulated G-CSF production in lipopolysaccharide (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e66cb80b89b89700c8b859f73ccb1eb6
https://doi.org/10.1046/j.1365-3083.1999.00575.x

A Framework for Evaluation and Exploration of Clustering Algorithms in Subspaces of High Dimensional Databases

Autor: Müller, E., Assent, I., Günnemann, S., Gerwert, P., Hannen, M., Jansen, T., Thomas Seidl

Publikováno v: Müller, E, Assent, I, Günnemann, S, Gerwert, P, Hannen, M, Jansen, T & Seidl, T 2011, A Framework for Evaluation and Exploration of Clustering Algorithms in Subspaces of High Dimensional Databases . in T Härder, W Lehner, B Mitschang, H Schöning & H Schwarz (eds), Proceedings of the 14th GI Conference on Database Systems for Business, Technology, and the Web (BTW 2011) . Gesellschaft für Informatik e.V., pp. 347-366, 14th BTW conference on Database Systems for Business, Technology and Web, Kaiserslautern, Germany, 02/03/2011 .
Aarhus University
Scopus-Elsevier

In high dimensional databases, traditional full space clustering methods are known to fail due to the curse of dimensionality. Thus, in recent years, subspace clustering and projected clustering approaches were proposed for clustering in high dimensi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::b8bdeeda5c34a25fa7db18136bda4af5
https://pure.au.dk/portal/da/publications/a-framework-for-evaluation-and-exploration-of-clustering-algorithms-in-subspaces-of-high-dimensional-databases(e552d19b-750c-4c94-9554-7133fc032bd9).html

Interleukin 10 inhibits TNF-alpha production in human monocytes independently of interleukin 12 and interleukin 1 beta

Autor: Halvard Bonig, J Verheyen, Hannen M, Ursula Banning, D.-I. Shin, Yong-Mi Kim, Dieter Körholz

Publikováno v: Immunological investigations. 28(2-3)

Previously we demonstrated that endogenously produced Interleukin (IL-)10 suppressed the production of tumor necrosis factor-alpha (TNF-alpha) in CD3 activated T-cells via down-regulation of paracrine IL-12 secretion from APC. Here we investigated th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::136c8a9c57b6075b1d869e4e19ac47b8
https://pubmed.ncbi.nlm.nih.gov/10484681

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