Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Hannelouise, Kissow"'
Autor:
Filip K Knop, Hannelouise Kissow, Maria Ebbesen Sørum, Anne Ortved Gang, Dorte Maegaard Tholstrup, Sif Gudbrandsdottir, Brian Kornblit, Klaus Müller
Publikováno v:
BMJ Open, Vol 14, Iss 10 (2024)
Introduction Cancer treatment with high-dose chemotherapy damages the mucosal barrier of the gastrointestinal (GI) tract and is associated with severe toxicity involving mucositis, severe inflammation and organ dysfunction. Currently, there is no eff
Externí odkaz:
https://doaj.org/article/187ce70753604e81b01dc5b63d6f665e
Autor:
Sana N. Buttar, Hasse Møller-Sørensen, Michael Perch, Hannelouise Kissow, Thomas N. B. Lilleør, Rene H. Petersen, Christian H. Møller
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 12 (2024)
The number of lung transplantations is limited due to the shortage of donor lungs fulfilling the standard criteria. The ex vivo lung perfusion (EVLP) technique provides the ability of re-evaluating and potentially improving and treating marginal dono
Externí odkaz:
https://doaj.org/article/fcb8b372a9cb4c50ab57917fde721353
Publikováno v:
Advances in Biomarker Sciences and Technology, Vol 6, Iss , Pp 72-82 (2024)
Background: Biliary atresia (BA) is a disease of the intrahepatic or extrahepatic bile ducts with an unknown etiology. It presents in neonates with jaundice, clay-colored stool, and often hepatomegaly. Early diagnosis of the disease is pivotal for lo
Externí odkaz:
https://doaj.org/article/eb015aff2b1a4935b592568f0816f3c3
Autor:
Mark M. Smits, Serafina I. L. Dreyer, Jenna E. Hunt, Anna K. Drzazga, Ida M. Modvig, Jens J. Holst, Hannelouise Kissow
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
ObjectiveFiber-free diet impairs intestinal and colonic health in mice, in parallel with a reduction in glucagon like peptide-1 (GLP-1) levels. Endogenous GLP-1 is important for intestinal growth and maintenance of the intestinal integrity. We aimed
Externí odkaz:
https://doaj.org/article/4196e0e25eeb4dd3af512886f69e4e99
Autor:
Jenna Elizabeth Hunt, Charlotte Bayer Christiansen, Mohammad Yassin, Bolette Hartmann, Stefan Offermanns, Lars Ove Dragsted, Jens Juul Holst, Hannelouise Kissow
Publikováno v:
Metabolites, Vol 14, Iss 7, p 395 (2024)
Short-chain fatty acids (SCFAs) are the major microbial metabolites produced from the fermentation of dietary fiber in the gut. They are recognised as secretagogues of the glucagon-like peptides, GLP-1 and GLP-2, likely mediated by the activation of
Externí odkaz:
https://doaj.org/article/bd11afd979d249969949e34732c9668d
Autor:
Katrine D. Galsgaard, Emilie Elmelund, Christian D. Johansen, Anna B. Bomholt, Hüsün S. Kizilkaya, Frederik Ceutz, Jenna E. Hunt, Hannelouise Kissow, Marie Winther-Sørensen, Charlotte M. Sørensen, Thomas Kruse, Jesper F. Lau, Mette M. Rosenkilde, Cathrine Ørskov, Christina Christoffersen, Jens J. Holst, Nicolai J. Wewer Albrechtsen
Publikováno v:
Molecular Metabolism, Vol 66, Iss , Pp 101639- (2022)
Objective: Treatment with glucagon receptor antagonists (GRAs) reduces blood glucose but causes dyslipidemia and accumulation of fat in the liver. We investigated the acute and chronic effects of glucagon on lipid metabolism in mice. Methods: Chronic
Externí odkaz:
https://doaj.org/article/a7ae536eaac7430393a76a080bee5d30
Autor:
Maria Ebbesen, Hannelouise Kissow, Bolette Hartmann, Katrine Kielsen, Kaspar Sørensen, Sara Elizabeth Stinson, Christine Frithioff-Bøjsøe, Cilius Esmann Fonvig, Jens-Christian Holm, Torben Hansen, Jens Juul Holst, Klaus Gottlob Müller
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Patients undergoing allogeneic hematopoietic stem cell transplantation (HSCT) are challenged with severe side effects, which are propagated by mucosal barrier disruption, and the related microbial translocation and systemic inflammation. Glucagon-lik
Externí odkaz:
https://doaj.org/article/e6ca6974d3cd471eaa5e0254ae39795b
Autor:
Jenna Elizabeth Hunt, Mohammad Yassin, Jørgen Olsen, Bolette Hartmann, Jens Juul Holst, Hannelouise Kissow
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Treatment with exogenous GLP-2 has been shown to accelerate the growth of intestinal adenomas and adenocarcinomas in experimental models of colonic neoplasia, however, the role of endogenous GLP-2 in tumor promotion is less well known. Mice with a gl
Externí odkaz:
https://doaj.org/article/8d61d88d32794d4bae336f40ba55689a
Autor:
Jenna Elizabeth Hunt, Bolette Hartmann, Kristina Schoonjans, Jens Juul Holst, Hannelouise Kissow
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Dietary fiber has been linked to improved gut health, yet the mechanisms behind this association remain poorly understood. One proposed mechanism is through its influence on the secretion of gut hormones, including glucagon-like peptide-1 (GLP-1) and
Externí odkaz:
https://doaj.org/article/5ff20c7024354f85823847b133a8b00d
Autor:
Sara L. Jepsen, Nicolai J. Wewer Albrechtsen, Johanne A. Windeløv, Katrine D. Galsgaard, Jenna E. Hunt, Thomas B. Farb, Hannelouise Kissow, Jens Pedersen, Carolyn F. Deacon, Rainer E. Martin, Jens J. Holst
Publikováno v:
JCI Insight, Vol 6, Iss 4 (2021)
Somatostatin (SS) inhibits glucagon-like peptide-1 (GLP-1) secretion in a paracrine manner. We hypothesized that blocking somatostatin subtype receptor 2 (SSTR2) and 5 (SSTR5) would improve glycemia by enhancing GLP-1 secretion. In the perfused mouse
Externí odkaz:
https://doaj.org/article/49e4ec3cf7a24f8eaa5ee947eda8a17d