Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Hannele Lahtinen"'
Autor:
Mart Saarma, Zaal Kokaia, Judith Thomas-Crusells, Hong Li, Avtandil Nanobashvili, Hannele Lahtinen, Matti S. Airaksinen, Juha Voipio, Tero Viitanen, Kai Kaila, Claudio Rivera
Publikováno v:
The Journal of Cell Biology
Pathophysiological activity and various kinds of traumatic insults are known to have deleterious long-term effects on neuronal Cl− regulation, which can lead to a suppression of fast postsynaptic GABAergic responses. Brain-derived neurotrophic fact
Autor:
Jouni Sirviö, Paavo Riekkinen, Aarne Ylinen, Ulla Lukkarinen, Riitta Miettinen, Hannele Lahtinen
Publikováno v:
European Journal of Pharmacology. 297:213-218
Sustained electrical stimulation of the perforant pathway was used to induce long-lasting hippocampal seizures in conscious rats. One hour prior to stimulation, rats were given i.p. injections of either saline or a commonly used antiepileptic drug, c
Autor:
Maria Mazurkiewicz, Paavo J. Riekkinen, Hannele Lahtinen, Jouni Sirviö, Paavo Riekkinen, Antti Haapalinna
Publikováno v:
Brain Research Bulletin. 35:451-455
The present study investigated how the systemic administration of alpha-2 adrenergic agents that modulate the function of the noradrenergic system in brain, affect rousal and sustained attention. Food-deprivated rats were trained to detect and respon
Publikováno v:
Brain Research. 625:93-99
Sustained electrical stimulation of the perforant pathway (PP) was used to induce hippocampal seizures in conscious rats. About 4.5 h prior to stimulation, animals were given i.p. injections of either saline or CGP 39551 (10 mg/kg), a competitive ant
Publikováno v:
Epilepsy Research. 15:91-99
Combining the methods of microdialysis and EEG recording, we have examined the effect of unilaterally, intracortically applied gamma-hydroxybutyrate (GHB) on frontal cortical EEG activity in freely moving rats. GHB, a natural endogenous GABA metaboli
Publikováno v:
Experimental Neurology. 121:193-199
Subcortical deafferentation of the rat hippocampus has been suggested to offer a model for developing limbic epilepsy. In the present study, the long-term effect of fimbria-fornix lesioning on the density and distribution of hippocampal N-methyl-D-as
Publikováno v:
Brain Research Bulletin. 31:311-318
According to electrophysiological studies, the subcortically denervated hippocampus has been suggested as a model for limbic epilepsy. We investigated a) whether fimbrial lesioning leads to any biochemical or morphological changes in the rat hippocam
Autor:
Z. Horváth, P. J. Riekkinen, Hannele Lahtinen, György Buzsáki, Tamás F. Freund, M. Hsu, Riitta Miettinen
Publikováno v:
Restorative Neurology and Neuroscience. 5:215-223
Degeneration within the hippocampus was examined at the light microscopic level using the Gallyas silver stain two, four or nine months after bilateral transection of the fimbria-fornix and commissural connections. At two or four months after the les
Publikováno v:
European Journal of Pharmacology. 229:269-272
The acute effects of the irreversible gamma-aminobutyric acid (GABA) transaminase inhibitor, gamma-vinyl GABA (Vigabatrin), were studied in the central nervous system of the rat. GABA concentrations were monitored in the hippocampus by implantation o
Publikováno v:
Neuroscience Letters. 146:215-218
The results of the present study indicate that D-cycloserine, a partial agonist at the glycine binding site, which is a positive modulation site of the N-methyl-D-aspartate receptor, could improve dose dependently the acquisition of a water maze task